<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP20686

Description Putative transcription elongation factor A protein 3
SequenceMTREEDLIRMAKKLDKMVSRNNMEGAMDLLTELKGFNMTLKLLQETRIGMSVNGIRKHCTDEEVIALAKVLIKDWKRLLDSGNSHAEKPAEGKNGLDSDKTAVSPNGSPCETQSRKESCDSKPTGQPVKRHSADTKPDRRESTDSKKSSSLPAKKLTGERRESHGSKTSQPGPPQRKPSFDSTERKGKLDAPKTPTTPTSPMSPSFSSAGGPLSPHLATGDSVRDKCIEMLAAALRTDNDFKDFPANCDGMAAEIEDHIYQEIKATDMKYKNRVRSRISNLKDPKNPGLRRNVLAGSIDLSRLASMSAEEMASDELKQLRNVLTQEAIREHQMAKTGGTSTDLLQCGKCKKRNCTYNQVQTRSADEPMTTFVLCNECGNRWKVSPFHVHGPITHTFALCGIISKTIY
Length407
PositionUnknown
OrganismScophthalmus maximus (Turbot) (Psetta maxima)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Neoteleostei> Acanthomorphata> Carangaria> Pleuronectiformes> Pleuronectoidei> Scophthalmidae> Scophthalmus.
Aromaticity0.03
Grand average of hydropathy-0.799
Instability index56.21
Isoelectric point9.16
Molecular weight44991.66
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
translation elongation factor activity	GO:0003746	IEA:UniProtKB-KW
zinc ion binding	GO:0008270	IEA:InterPro

GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro
transcription, DNA-templated	GO:0006351	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP20686
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      96.44|      20|      23|     138|     159|       1
---------------------------------------------------------------------------
  115-  133 (35.20/12.88)	RKESCDSKPTGQ.PVKRHSA
  139-  158 (33.53/15.76)	RRESTDSKKSSSLPAKKLTG
  160-  176 (27.71/ 8.34)	RRESHGSKTSQPGPPQR...
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      76.29|      22|      26|     349|     374|       2
---------------------------------------------------------------------------
  349-  374 (35.55/34.59)	CKKRnctyNQVQTRSADEPMT.TFVLC
  377-  399 (40.74/26.55)	CGNR....WKVSPFHVHGPIThTFALC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      35.02|      10|      27|     178|     189|       3
---------------------------------------------------------------------------
  178-  189 (14.80/14.18)	PSFDSTErkGKL
  204-  213 (20.22/11.59)	PSFSSAG..GPL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.29|      18|      27|     276|     302|       4
---------------------------------------------------------------------------
  276-  294 (25.71/36.03)	SRISNLKDPKNPGLRrNVL
  306-  323 (28.58/12.63)	MSAEEMASDELKQLR.NVL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.22|      15|      18|      76|      93|       5
---------------------------------------------------------------------------
   79-   93 (26.72/17.26)	LDSGN...SHAEKPAEGK
   96-  113 (23.49/ 7.23)	LDSDKtavSPNGSPCETQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.70|      16|      18|     217|     233|       6
---------------------------------------------------------------------------
  217-  233 (24.21/18.59)	LATGDSVRD...KCIEMlAA
  235-  253 (25.48/14.72)	LRTDNDFKDfpaNCDGM.AA
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP20686 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) LLDSGNSHAEKPAEGKNGLDSDKTAVSPNGSPCETQSRKESCDSKPTGQPVKRHSADTKPDRRESTDSKKSSSLPAKKLTGERRESHGSKTSQPGPPQRKPSFDSTERKGKLDAPKTPTTPTSPMSPSFSSAGGPLSPHLATGDSVRD
78
225










Molecular Recognition Features






MoRF SequenceStartStop




NANANA