<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP20685

Description Putative transcription elongation factor A protein 3 isoform 2
SequenceMTREEDLIRMAKKLDKMVSRNNMEGAMDLLTELKGFNMTLKLLQETRIGMSVNGIRKHCTDEEVIALAKVLIKDWKRLLDSGNSHAEKPAEGKNGLDSDKTAVSPNGSPCETQSRKESCDSKPTGQPVKRHSADTKPDRRESTDSKKSSSLPAKKLTGERRESHGSKTSQPGPPQRKPSFDSTERKGKLDAPKTPTTPTSPMSPSFSSAGGPLSPHLATGDSVRDKCIEMLAAALRTDNDFKDFPANCDGMAAEIEDHIYQEIKATDMKYKNRVRSRISNLKDPKNPGLRRNVLAGSIDLSRLASMSAEEMASDELKQLRNVLTQEAIREHQMAKTGGTSTDLLQCGKCKKRNCTYNQVQTRSADEPMTTFVLCNECGNRWKFC
Length384
PositionUnknown
OrganismScophthalmus maximus (Turbot) (Psetta maxima)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Neoteleostei> Acanthomorphata> Carangaria> Pleuronectiformes> Pleuronectoidei> Scophthalmidae> Scophthalmus.
Aromaticity0.03
Grand average of hydropathy-0.878
Instability index57.92
Isoelectric point9.12
Molecular weight42520.80
Publications

Function

Annotated function
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell
GO - Biological Function
translation elongation factor activity	GO:0003746	IEA:UniProtKB-KW
zinc ion binding	GO:0008270	IEA:InterPro
GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro
transcription, DNA-templated	GO:0006351	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP20685
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     101.64|      24|      24|     159|     182|       1
---------------------------------------------------------------------------
   97-  121 (24.06/ 8.88)	...DS.DKTAV.SPNGSPcetqSRKESCDS
  159-  182 (47.40/24.05)	ERRES.HGSKT.SQPGPP....QRKPSFDS
  184-  208 (30.18/12.86)	ERKGKlDAPKTpTTPTSP....M.SPSFSS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.82|      13|      17|     213|     225|       4
---------------------------------------------------------------------------
  213-  225 (22.51/15.76)	LSPHLATGDSVRD
  231-  243 (21.31/14.54)	LAAALRTDNDFKD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.06|      12|      25|     341|     352|       5
---------------------------------------------------------------------------
  341-  352 (22.67/12.30)	TDLLQCGKCKKR
  369-  380 (23.39/12.88)	TTFVLCNECGNR
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP20685 with Med26 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) LLDSGNSHAEKPAEGKNGLDSDKTAVSPNGSPCETQSRKESCDSKPTGQPVKRHSADTKPDRRESTDSKKSSSLPAKKLTGERRESHGSKTSQPGPPQRKPSFDSTERKGKLDAPKTPTTPTSPMSPSFSSAGGPLSPHLATGDSVRD
78
225

Molecular Recognition Features

MoRF SequenceStartStop
NANANA