<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP20670

Description Mediator of RNA polymerase II transcription subunit 13
SequenceMRYTVNIYFSKFIYLYGSLFLVFSRKNSQNCCNFLYFFQAELTGIKWRRYNFGGHGDCGPIISAPAQDDPILLSFIRCLQANLLCVWRRDVKPDCKELWIFWWGDEPNLVGVIHHELQVVEEGLWENGLSYECRTLLFKAIHNLLERCLMDKNFVRIGKWFVRPYEKDEKPVNKSEHLSCAFTFFLHGESNVCTSVEIAQHQPIYLINEEHIHMAQSSPAPFQVLVSPYGLNGTLTGQAYKMSDPATRKLIEEWQYFYPMVLKKKEELKEEEELGYDDDFPVAVEVIVGGVRMVYPSAFVLISQNDLPVPQSVAGTGGHITVGQQGLGSVKDPSNCGMPLTPPTSPEQAVIGESGGTQSAVSHLGSQDGGMITMHSPKRSGKIPPKLHNHMVHRVWKECILNRTQSKRSQMSTPTLEEEPANNPATWDFVDPTQRVSCSCSRHKLLKRCAVGPSRPPTISQPGFSAGPSSSSSLPPPASSKHKTTERQEKGDKLQKRPLIPFHHRPSVAEELCMEQDPPGQKLGLAGIDSSLEVASSRKYDKQMAVPSRNTSKQMNLNPMDSPHSPISPLPPTLSPQPRGQETENLDPPSVPVNPALYGNGLELQQLSTLDDRTVLVGQRLPLMAEVSETALYCGIRPSNPESSDKWWHSYHLPSIDDAEFRPPELQGERCDAKMEVNSESTALQRLLAQPNKRFKIWQDKQPQMQPLHFLDPLPLSQQPGDSLGEVNDPYTFEDGDIKYIFTANKKCKQGTEKDSLKKNKSEDGFGTKDVTTPGHSTPVPEGKNAMSLFSSTKTDVRQDSAAGRAGSSSLTQVTDLAPSLHDLDNIFDNSDDDELGAVSPALRSSKMPTVGTEDRPLGKDGRAAVPYPPTVADLQRMFPTPPSLEQHPAFSPVMNYKDGISSETVTALGMMESPMVSMVSTQLTEFKVEVEDGLGSPKPEEIKDFSYVHKVPTLQPFVGSSMFAPLKMLPSQCLLPLKIPDACLFRPSWAIPPKIEQLPMPPAATFIRDGYNNVPSVGSLADPDYLNTPQMNTPVTLNSAAPASNSGAGVLPSPATPRFSVPTPRTPRTPRTPRGGGTASGQGSVKYDSTDQGSPASTPSTTRPLNSVEPATMQPIPEAHSLYVTLILSDSVMNIFKDRNFDSCCICACNMNIKGADVGLYIPDSSNEDQYRCTCGFSAIMNRKLGYNSGLFLEDELDIFGKNSDIGQAAERRLMMCQTTFLPQMEGARKSQEPPISLLLLLQNQHTQPFASLSFLDYISCNNRQTLPCVSWSYDRVQADNNDYWTECFNALEQGRQYVDNPTGGKVDEALVRSATVHSWPHSNVLDISMLSSQDVVRMLLSLQPFLQDAIQKKRTGRTWENIQHVQGPLTWQQFHKMAGRGTYGSEESPEPLPIPTLLVGYDKDFLTISPFSLPFWERLLLDPYGGHRDVAYIVVCPENEALLEGAKTFFRDLSAVYEMCRLGQHKPICKVLRDGIMRVGKTVAQKLAEELVSEWFNQPWGSEESDNHSRLKLYAQVCRHHLGFSGSVGAQNPSAGASSAERTQGNIGCGGDTEPGQSSSQPSQDGQESVTERERIGIPTEPDSADSQAYPPAVVIYMVDPFTYTAEEDSTSGNFWLLSLMRCYTEMLDNLPEHMRNSFILQIVPCQYMLQTMKDEQVFYIQYLKSMAFSVYCQCRRPLPTQIHIKSLTGFGPAASIEMTLKNPERPSPIQLYSPPFILAPIKDKQTELGETFGEASQKYNVLFVGYCLSHDQRWLLASCTDLHGELLETCIVNIALPNRSRRSKVSARKIGLQKLWEWCIGIVQMTSLPWRVVIGRLGRLGHGELKDWSILLGECSLQTISKRLKDVCRMCGISAADSPSILSACLVAMEPQGSFVVMPDAVTMGSVFGRSTALNMQSSQLNTPQDASCTHILVFPTSSTIQVAPANYPNEDGFSPNNDDMFVDLPFPDDMDNDIGILMTGNLHSSPNSSPVPSPGSPSGIGVGSHFQHSRSQGERLLSREAPEELKQQPLALGYFVSTAKAENLPQWFWSSCPQAQNQCPLFLKASLHHHISVAQTDELLPARNSQRVPHPLDSKTTSDVLRFVLEQYNALSWLTCNPATQDRTSCLPVHFVVLTQLYNAIMNIL
Length2129
PositionMiddle
OrganismTursiops truncatus (Atlantic bottle-nosed dolphin) (Delphinus truncatus)
KingdomMetazoa
Lineage
Aromaticity0.08
Grand average of hydropathy-0.384
Instability index58.57
Isoelectric point5.74
Molecular weight236041.28
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP20670
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.57|      17|      28|     378|     405|       1
---------------------------------------------------------------------------
  378-  394 (31.67/ 8.78)	KRSGKIPPKLHNHMVHR
  407-  423 (29.90/25.85)	KRSQMSTPTLEEEPANN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     162.38|      28|      28|    1048|    1075|       2
---------------------------------------------------------------------------
  424-  465 (27.12/ 7.86)	..PATWDFVDPTQRVScscsrhkllkrcavgpsRPP.TISQPGFS
  466-  487 (26.14/ 7.30)	AGPSSSS.SLPPPASS.................KHKTTER.....
 1029- 1052 (29.03/ 8.95)	....TPQMNTPVTLNS.................AAPASNSGAGVL
 1053- 1080 (51.34/21.63)	PSPATPRFSVPTPRTP.................RTPRTPRGGGTA
 1969- 1987 (28.75/ 8.79)	....SPN.SSPVP.....................SPGSPSGIGVG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.57|      12|      26|    1552|    1563|       3
---------------------------------------------------------------------------
 1552- 1563 (23.76/14.70)	GGDTEPGQSSSQ
 1579- 1590 (21.81/12.70)	GIPTEPDSADSQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     100.16|      27|      62|      12|      38|       4
---------------------------------------------------------------------------
   12-   38 (51.17/33.79)	FIY.LYGSLFLVFSRKNSQNCCNFLYFF
   75-  102 (48.99/32.00)	FIRcLQANLLCVWRRDVKPDCKELWIFW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.06|      19|     141|     558|     581|       5
---------------------------------------------------------------------------
  569-  595 (33.79/15.47)	PLPPTLSPQPRgqetenldPPSVPVNP
  867-  889 (31.27/ 8.97)	PYPPTVADLQR....mfptPPSLEQHP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      75.04|      23|      26|    1659|    1684|       6
---------------------------------------------------------------------------
 1662- 1684 (44.77/33.51)	YIQYLKSM..AFSVYCQCR...RPLPTQ
 1686- 1713 (30.27/12.48)	HIKSLTGFgpAASIEMTLKnpeRPSPIQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      69.10|      20|      22|     963|     983|       7
---------------------------------------------------------------------------
  963-  983 (34.45/19.90)	MFAPLKMLPSQC.LLPLKiPDA
  985- 1005 (34.64/16.03)	LFRPSWAIPPKIeQLPMP.PAA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.41|      14|      17|     240|     255|       8
---------------------------------------------------------------------------
  240-  253 (24.00/22.71)	YKMSDPATRKLIEE
  258-  271 (23.41/11.07)	YPMVLKKKEELKEE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.55|      10|     912|     195|     204|      11
---------------------------------------------------------------------------
  195-  204 (19.55/11.04)	SVEIAQHQPI
 1108- 1117 (20.00/11.48)	SVEPATMQPI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      79.19|      18|      22|    1919|    1936|      12
---------------------------------------------------------------------------
 1895- 1911 (21.38/ 9.41)	.TALNMQSS...QLNTPQDAS
 1919- 1936 (31.10/17.38)	PTSSTIQVA...PANYPNEDG
 1939- 1959 (26.70/13.77)	PNNDDMFVDlpfPDDMDNDIG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.34|      12|      27|    1792|    1803|      13
---------------------------------------------------------------------------
 1792- 1803 (24.58/15.50)	KIGLQKLWEWCI
 1822- 1833 (22.75/13.71)	RLGHGELKDWSI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      93.14|      22|     136|     533|     554|      14
---------------------------------------------------------------------------
  533-  554 (36.89/23.52)	EVASSRKYDKQMAVPSRNTSKQ
  643-  660 (22.71/11.38)	...SSDKWWHSYHLPSIDDAE.
  665-  685 (33.54/20.65)	ELQGER.CDAKMEVNSESTALQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     101.61|      29|     634|    1387|    1418|      15
---------------------------------------------------------------------------
 1387- 1418 (51.42/40.36)	SEESPEPLPIPTLLVGYdkdFL.TISPFSLPFW
 2002- 2031 (50.18/30.67)	SREAPEELKQQPLALGY...FVsTAKAENLPQW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      73.09|      20|    1372|      52|      72|      22
---------------------------------------------------------------------------
   52-   72 (35.62/22.33)	FGGHGDCGPIISAPaQDDPIL
 1426- 1445 (37.47/19.44)	YGGHRDVAYIVVCP.ENEALL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.08|      17|     134|    1618|    1635|      23
---------------------------------------------------------------------------
 1618- 1635 (26.88/21.91)	WLLSLMRCyTEMLDNLPE
 1641- 1657 (31.20/19.54)	FILQIVPC.QYMLQTMKD
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP20670 with Med13 domain of Kingdom Metazoa
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