<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP20666

Description Mediator of RNA polymerase II transcription subunit 13
SequenceMRYTVNIYFSKFIYLYGSLFLVFSRKNSQNCCNFLYFFQAELTGIKWRRYNFGGHGDCGPIISAPAQDDPILLSFIRCLQANLLCVWRRDVKPDCKELWIFWWGDEPNLVGVIHHELQVVEEGLWENGLSYECRTLLFKAIHNLLERCLMDKNFVRIGKWFVRPYEKDEKPVNKSEHLSCAFTFFLHGESNVCTSVEIAQHQPIYLINEEHIHMAQSSPAPFQVLVSPYGLNGTLTGQAYKMSDPATRKLIEEWQYFYPMVLKKKEELKEEEELGYDDDFPVAVEVIVGGVRMVYPSAFVLISQNDLPVPQSVAGTGGHITVGQQGLGSVKDPSNCGMPLTPPTSPEQAVIGESGGTQSAVSHLGSQDGGMITMHSPKRSGKIPPKLHNHMVHRVWKECILNRTQSKRSQMSTPTLEEEPANNPATWDFVDPTQRVSCSCSRHKLLKRCAVGPSRPPTISQPGFSAGPSSSSSLPPPASSKHKTTERQEKGDKLQKRPLIPFHHRPSVAEELCMEQDPPGQKLGLAGIDSSLEVASSRKYDKQMAVPSRNTSKQMNLNPMDSPHSPISPLPPTLSPQPRGQETENLDPPSVPVNPALYGNGLELQQLSTLDDRTVLVGQRLPLMAEVSETALYCGIRPSNPESSDKWWHSYHLPSIDDAEFRPPELQGERCDAKMEVNSESTALQRLLAQPNKRFKIWQDKQPQMQPLHFLDPLPLSQQPGDSLGEVNDPYTFEDGDIKYIFTANKKCKQGTEKDSLKKNKSEDGFGTKDVTTPGHSTPVPEGKNAMSLFSSTKTDVRQDSAAGRAGSSSLTQVTDLAPSLHDLDNIFDNSDDDELGAVSPALRSSKMPTVGTEDRPLGKDGRAAVPYPPTVADLQRMFPTPPSLEQHPAFSPVMNYKDGISSETVTALGMMESPMVSMVSTQLTEFKVEVEDGLGSPKPEEIKDFSYVHKVPTLQPFVGSSMFAPLKMLPSQCLLPLKIPDACLFRPSWAIPPKIEQLPMPPAATFIRDGYNNVPSVGSLADPDYLNTPQMNTPVTLNSAAPASNSGAGVLPSPATPRFSVPTPRTPRTPRTPRGGGTASGQGSVKYDSTDQGSPASTPSTTRPLNSVEPATMQPIPEAHSLYVTLILSDSVMNIFKDRNFDSCCICACNMNIKGADVGLYIPDSSNEDQYRCTCGFSAIMNRKLGYNSGLFLEDELDIFGKNSDIGQAAERRLMMCQTTFLPQMEGARKSQEPPISLLLLLQNQHTQPFASLSFLDYISCNNRQTLPCVSWSYDRVQADNNDYWTECFNALEQGRQYVDNPTGGKVDEALVRSATVHSWPHSNVLDISMLSSQDVVRMLLSLQPFLQDAIQKKRTGRTWENIQHVQGPLTWQQFHKMAGRGTYGSEESPEPLPIPTLLVGYDKDFLTISPFSLPFWERLLLDPYGGHRDVAYIVVCPENEALLEGAKTFFRDLSAVYEMCRLGQHKPICKVLRDGIMRVGKTVAQKLAEELVSEWFNQPWGSEESDNHSRLKLYAQVCRHHLAPYLATLQLDSSLLIPPKYQTPPAAAQGQATPGNAGPLASNPGSAAPSAGSAFNPTSNGSSVNPAASSSASGSSVPPASTSASAPIINQISTTSSSGFSGSVGAQNPSAGASSAERTQGNIGCGGDTEPGQSSSQPSQDGQESVTERERIGIPTEPDSADSQAYPPAVVIYMVDPFTYTAEEDSTSGNFWLLSLMRCYTEMLDNLPEHMRNSFILQIVPCQYMLQTMKDEQVFYIQYLKSMAFSVYCQCRRPLPTQIHIKSLTGFGPAASIEMTLKNPERPSPIQLYSPPFILAPIKDKQTELGETFGEASQKYNVLFVGYCLSHDQRWLLASCTDLHGELLETCIVNIALPNRSRRSKVSARKIGLQKLWEWCIGIVQMTSLPWRVVIGRLGRLGHGELKDAVTMGSVFGRSTALNMQSSQLNTPQDASCTHILVFPTSSTIQVAPANYPNEDGFSPNNDDMFVDLPFPDDMDNDIGILMTGNLHSSPNSSPVPSPGSPSGIGVGSHFQHSRSQGERLLSREAPEELKQQPLALGYFVSTAKAENLPQWFWSSCPQAQNQCPLFLKASLHHHISVAQTDELLPARNSQRVPHPLDSKTTSDVLRFVLEQYNALSWLTCNPATQDRTSCLPVHFVVLTQLYNAIMNIL
Length2172
PositionMiddle
OrganismTursiops truncatus (Atlantic bottle-nosed dolphin) (Delphinus truncatus)
KingdomMetazoa
Lineage
Aromaticity0.08
Grand average of hydropathy-0.395
Instability index57.71
Isoelectric point5.76
Molecular weight239434.32
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP20666
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|    1714.56|     502|     576|     949|    1523|       1
---------------------------------------------------------------------------
  457-  650 (195.11/85.14)	PTISQPGF..SAGPSSSSS...LPPPASSKHKtterqekgdklqkrplIPFHHRPSV.AEELCMEQDPPGQklglagidsslevaSSRKYD..KQMAVPSRnTSKQMNLNPMDsphspisplP..PTLSPQP.............................................................................................................................................................................................................................................................................................................................................rGQ.......ETE.NLDPPSVPVNPALY.GNGLELQQLSTLDDRTVLvGQRLPLMAEVSETALYCG..IRPSNPES.SDKW....WHS...............................................................................................
 1030- 1597 (787.96/493.83)	PQMNTPVTLNSAAPASNSGAgvLPSPATPRFS................VPTPRTPRT.PRTPRGGGTASGQ..............GSVKYDSTDQGSPAST.PSTTRPLNSVE.........P..ATMQPIPEAHSLYVTLILSDSVMNIFKDRNFDSCCICAC......NM..NIKGADVGLYIPdssnedqyrCTCGFSAIMNRKLGYNSglFLEDEldIFGKNSDIGQAAERRLMMCQTT.FLP..QMEGARKSQE.P.PISL....LLLLQNQHTQPFASLSFLDYISCNNRQTLP.CVSWSYDRVQADNNDYWTEcfnALEQGRQYVDNPTGGKVDEALVRSATVHS.WPHS.NVLDISMLSSQDVVRMLLSL.QPFLQDAIQKKRT.GR.TWENIQHVQ..GPLTWQQFHKMAGRGTYGSEESPEPLPIPTLLVGYDKDFLTispfSLPFWERllLDPY.GG.......HRD.VAYIVVCPENEALLeGAKTFFRDLSAVYEMCRL.GQHKPICKVLRDGIMRVGKTVAQKLAEELVSEWFnqpWGS.EESDNHSRLKLYAQVcRHHlapylatlqldssllippKyQTPPAAAQGQatpgnagplasNPGSAAPsagsafnPTSNGSSVNPAASSSASG.S
 1609- 2136 (731.49/377.94)	PIINQISTTSSSGFSGSVGA...QNP.....S................AGASSAERTqGNIGCGGDTEPGQ..............SSSQPSQDGQESVTER.ERIGIP...TE.........PdsADSQAYPPAVVIYMVDPFTYTAEEDSTSGNFWLLSLMRCytemldNLpeHMRNSFILQIVP.........CQYMLQTMKDEQVFYIQ..YLKSM..AFSVYCQCRRPLPTQIHIKSLTgFGPaaSIEMTLKNPErPsPIQLysppFILAPIKDKQTELGETFGEASQKYNVLFVGyCLSHDQRWLLASCTDLHGE...LLETCIVNIALPNRSRRSKVSARKIGLQKlWEWCiGIVQMTSLPWRVVIGRLGRLgHGELKDAVTMGSVfGRsTALNMQSSQlnTPQDASCTHILVFPTSSTIQVAPANYPNEDGFSPNNDDMFV....DLPFPDD..MDND.IGilmtgnlHSSpNSSPVPSPGSPSGI.GVGSHFQHSRSQGERL.L.SREAP..EELKQQPLALGYFVSTAKAENL.PQWF...WSScPQAQNQCPLFLKASL.HHH.................iS.VAQTDELLPA...........RNSQRVP.......HPLDSKTTSDVLRFVLEQyN
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     141.19|      21|      68|      77|      97|       2
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   15-   33 (22.53/10.84)	..L.YGSLFLV............FSR...KNSQNCCN
   36-   60 (26.97/14.66)	YFF.QAELTGI...........kWRRynfGGHGDCGP
   77-   97 (38.76/24.82)	RCL.QANLLCV............WRR...DVKPDCKE
  103-  135 (25.88/13.73)	WGD.EPNLVGVihhelqvveeglWEN...GLSYECRT
  147-  168 (27.05/14.73)	RCLmDKNFVRI............GKW...FVRPYEKD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     204.71|      60|     394|     302|     384|       3
---------------------------------------------------------------------------
  302-  369 (93.76/70.19)	ISQNDLPVPQ.SVAGTGGHITVGQQ...GLGSVKD..PSncgmpLTPP........TSPEQAvigESGGTQSAVSHLGSQDG
  697-  765 (89.09/46.65)	IWQDKQPQMQ.PLHFL.DPLPLSQQpgdSLGEVND..P......YTFEdgdikyifTANKKC...KQGTEKDSLKKNKSEDG
  790-  820 (21.86/18.31)	FSSTKTDVRQdSAAGRAGSSSLTQ........VTDlaPS...........................................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.41|      14|      17|     240|     255|       4
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  240-  253 (24.00/16.93)	YKMSDPATRKLIEE
  258-  271 (23.41/ 8.15)	YPMVLKKKEELKEE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.85|      12|     545|     983|     994|       5
---------------------------------------------------------------------------
  983-  994 (24.33/12.70)	ACLFRPSWAIPP
 1005- 1016 (19.52/ 8.62)	ATFIRDGYNNVP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     159.71|      47|      70|     846|     893|       6
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  846-  893 (82.71/39.62)	SKMPTVGTEDRPLGKDGRAAvPYPPTVADLQRM..FPTPPSLEQHPAFSP
  918-  966 (77.00/33.54)	SMVSTQLTEFKVEVEDGLGS.PKPEEIKDFSYVhkVPTLQPFVGSSMFAP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.43|      12|      26|     378|     389|       7
---------------------------------------------------------------------------
  378-  389 (22.36/13.26)	KRSGKIPPKLHN
  407-  418 (21.06/11.97)	KRSQMSTPTLEE
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP20666 with Med13 domain of Kingdom Metazoa
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