<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP20622

Description cyclin-dependent kinase 19 isoform X1
SequenceMAVSGPKKECTLSCRVYHTSLCEIPGGLRVWTSSVGGSRLFSRRKDEKEYALKQIEGTGISMSACREIALLRELKHPNVIALQKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPFHHDQLDRIFSVMGFPADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYMEKHKVKPDSKVFLLLQKLLTMDPTKRITSEQALQDPYFQEDPLPTLDVFAGCQIPYPKREFLNEDEPEEKGDKNQQQQQNQHPQPAAPPQQAAAPPQAAPQQQNSTQANGTAGGAGAGPGAAGAGLQHSQDSGLNQVPPNKKPRLGPSGTNSGGPVMPSDYQHSSSRLNYQSSVQGSSQSQSSLGYSSSSQQSAQYHPSHQAHRY
Length503
PositionKinase
OrganismTursiops truncatus (Atlantic bottle-nosed dolphin) (Delphinus truncatus)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Laurasiatheria> Artiodactyla> Whippomorpha> Cetacea> Odontoceti> Delphinidae> Tursiops.
Aromaticity0.08
Grand average of hydropathy-0.606
Instability index58.75
Isoelectric point9.00
Molecular weight56436.39
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein kinase activity	GO:0004672	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP20622
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     121.31|      28|      41|     434|     461|       1
---------------------------------------------------------------------------
  393-  426 (28.22/10.92)	..PPQAAPQQqnstqanG.TAGGAGAGPgAAGAGLQH
  434-  461 (52.75/26.43)	QVPPNKKPRL.......G.PSGTNSGGP.VMPSDYQH
  473-  501 (40.34/18.59)	QGSSQSQSSL.......GySSSSQQSAQ.YHPSHQAH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.44|      15|      41|     152|     166|       2
---------------------------------------------------------------------------
  152-  166 (26.77/19.78)	DLKPANILVMGEGPE
  190-  204 (28.67/21.72)	DLDPVVVTFWYRAPE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      93.61|      28|      41|     315|     342|       3
---------------------------------------------------------------------------
  315-  342 (48.12/27.12)	KLLTMD.PTKRITSEQALQDPYFQEDPLP
  358-  386 (45.49/25.25)	EFLNEDePEEKGDKNQQQQQNQHPQPAAP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP20622 with CDK8 domain of Kingdom Metazoa
Unable to open file!