<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP20616

Description Mediator of RNA polymerase II transcription subunit 15
SequenceMPGFFDPWRLDLTVFPSGWKLLGPAFSAPPCTPCPDNKKSQASVSAQLQLQQVALQQQQQQFQAQQQAALQQQQQQQFQVQQSAMQQQFQAVVQQQQLQQQQQQQHLIKLHHQNQQQVLDAIVLDPGLLQGPRAWDENEWAYCVPGDGSGGSWCRQFMRDISQGSGGKPTPLLKESLETPAPTDRRGGALPCALVAPDCCSLPPQVRAPMVVQQPQVQPQVPQVQPQVPPQTAVPTAQASQIVGPGVQVSQSGLTMLSSPSPGQQVQTPQSMPPPPQPSPQPGPPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQYLDKLKQLSKYIEPLRRMINKIDKNEDRKKDLSKMKSLLDILTDPSKRCPLKTLQKCEIALEKLKNDMAVPTPPPPPVPPTKQQYLCQPLLDAVLANIRSPVFNHSLYRTFVPAMTAIHGPPITAPVVCTRKRRFEEDERQSIPNVLQGEVARLDPKFLVNLDPSHCSNNGTVHLICKLDDKDLPSVPPLELSVPADYPAQSPLWIDRQWQYDANPFLQSVHRCMTSRLLQLPDKHSVTALLNTWAQSIHQACLSAA
Length612
PositionTail
OrganismTursiops truncatus (Atlantic bottle-nosed dolphin) (Delphinus truncatus)
KingdomMetazoa
Lineage
Aromaticity0.05
Grand average of hydropathy-0.541
Instability index79.81
Isoelectric point8.43
Molecular weight67172.74
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP20616
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     126.21|      27|      27|      51|      77|       1
---------------------------------------------------------------------------
   51-   77 (50.70/14.52)	QQVALQ........QQQQQFQAQ..QQAALQQQQQQQ
  213-  241 (41.17/10.42)	QQPQVQ........PQVPQVQPQvpPQTAVPTAQASQ
  250-  281 (34.34/ 7.48)	SQSGLTmlsspspgQQVQT...P..QSMPPPPQPSPQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      91.32|      17|      19|     301|     317|       3
---------------------------------------------------------------------------
   16-   34 (25.12/ 7.38)	PSGWklLgPAFSAPPC.TPC
  301-  317 (34.93/13.52)	PSSF..L.PSPSPQPSQSPV
  322-  337 (31.27/11.23)	PQNF....SVPSPGPLNTPV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      56.70|      14|     116|     391|     404|       4
---------------------------------------------------------------------------
  357-  370 (22.52/14.81)	LDKLKQLSKYI....EPL
  377-  393 (14.75/ 7.06)	IDKNEDRKKD.lskmKSL
  394-  409 (19.44/11.74)	LDILTDPSKRC..plKTL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.87|      16|      47|     424|     439|       5
---------------------------------------------------------------------------
  424-  439 (33.17/14.50)	AVPTPP.PPPVPPTKQQ
  472-  488 (26.70/10.04)	AIHGPPiTAPVVCTRKR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.20|      18|      20|      79|      98|       6
---------------------------------------------------------------------------
   79-   98 (27.26/18.68)	QVQQSAMQQQFQAvvQQQQL
  102-  119 (32.94/17.09)	QQQQHLIKLHHQN..QQQVL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      90.03|      25|      36|     130|     154|       7
---------------------------------------------------------------------------
  130-  154 (53.83/31.22)	QG....PRAWDENEWAYCVPGDGSGGSW.C
  163-  192 (36.20/18.66)	QGsggkPTPLLKESLETPAPTDRRGGALpC
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP20616 with Med15 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) PQVRAPMVVQQPQVQPQVPQVQPQVPPQTAVPTAQASQIVGPGVQVSQSGLTMLSSPSPGQQVQTPQSMPPPPQPSPQPGPPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQYLDKLKQ
204
362










Molecular Recognition Features






MoRF SequenceStartStop




NANANA