<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP20613

Description LOW QUALITY PROTEIN: disintegrin and metalloproteinase domain-containing protein 20-like
SequenceMAAVDIRDNLLGISWVDSSWIPILNSGSVLDYFSERSNPFYDRTCNNEVVKMQRLTLEHLNQMVGVEYILLHAQEPILFIIRKQQRQSPTQVIPLADYYIIAGVIYQAPDLGSVINSRVLTVVHGIQSAFDEAMSYCRYHPSKGYWWHFKDHEEQDKVKPKVKRKEEPSSIFQRQRVDALLLDLRQKFPPRFVQQKSGEKPVPVDQTKKEAEPIPETVKSEEKETTKNVQQTVGTKGPPEKRMRLHTEALMVHLFQDIDPXKGQPCTLNSSEGGARPVAPDALPSSALNRCLHNXAVGEALVHIRATLLLLSFGVSLFISDHSQARASQHFSSPELVIPLKVTGRGRNAKAPGWLSYSLRFGGQRHIAHMRVKKFLVSRYLPVFTYTDQRALRQDQPFVPDDCYYHGYVEGVPKSLVALSTCSGGFRGILQINDLAYEIEPVRFSATFEHWVYKIDSDDTQFPPMRCGLTEEDIARQLELQELHNFTLMQSSYTGWWTHLRFLELVVVVDNLRFVHSESNVSVVQREILDVVNIIGSLYHSLELVVILTGLEVWTKGNPVPIDNIDKLLEDFSVWKYFSLDHRLSHDAAHLFIKKSFGITLGVAYVGGICQRPLNSGVNVFEDESLYAFAIVVTHELGHNLGMRHDTEWCVCELQWCIMFPAREVTNKFSNCSYAEYWDNLISNGLCLYSPPHPGNIFRLKYCGNLVVEEGEECDCGTIEQCKNDPCCLLNCTLKPGAACAFGLCCKDCKVMSSGTLCRKQVSECDLPEWCNGTSHQCPEDVYVQDGIPCSDGAYCYQKSCNNHDEQCREIFGKDARSAPQSCYKEINTQGNRFGHCGIKDTQYVKCASPDILCGRVQCENVGVIPNLIEHSTVHQLHFNDTTCWGTDYHMGMSISDIGQVKDGTMCGPGKICVRNKCVSMVRVPQACQPETCHMKGICNNKQQCHCNPGWAPPYCEQQGNGGSNSSGPPFNPQAEETGLKEKGKQPLLWLIPLTCLFLRCIFVLYEKHKKEEAETMEEKETEEEEGD
Length1028
PositionHead
OrganismTursiops truncatus (Atlantic bottle-nosed dolphin) (Delphinus truncatus)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Laurasiatheria> Artiodactyla> Whippomorpha> Cetacea> Odontoceti> Delphinidae> Tursiops.
Aromaticity0.09
Grand average of hydropathy-0.330
Instability index45.04
Isoelectric point5.95
Molecular weight115882.90
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP20613
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      96.16|      24|     272|     652|     678|       1
---------------------------------------------------------------------------
  652-  678 (43.34/35.25)	CELQWCIMfpaREVTNKFSNCSYAEYW
  928-  951 (52.82/33.50)	CQPETCHM...KGICNNKQQCHCNPGW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.57|      20|     272|     167|     190|       2
---------------------------------------------------------------------------
  167-  190 (29.42/27.95)	EP...SSIFQR..QRVDAlllDLRQkFPP
  440-  464 (30.15/16.46)	EPvrfSATFEHwvYKIDS...DDTQ.FPP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      70.33|      20|     303|       2|      21|       3
---------------------------------------------------------------------------
    2-   21 (37.04/22.07)	AAVDIRDNLLGISWVDSSWI
  300-  319 (33.30/19.21)	ALVHIRATLLLLSFGVSLFI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.85|      11|      15|     953|     963|       6
---------------------------------------------------------------------------
  953-  963 (23.86/13.24)	PPYCEQQGNGG
  969-  979 (21.99/11.61)	PPFNPQAEETG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.93|      13|      15|     727|     740|       7
---------------------------------------------------------------------------
  727-  740 (22.71/12.68)	CClLNCT.LKPGAAC
  745-  758 (22.22/ 8.46)	CC.KDCKvMSSGTLC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.37|      11|      34|     193|     203|       8
---------------------------------------------------------------------------
  193-  203 (20.93/12.89)	VQQKSGEKPVP
  229-  239 (21.43/13.38)	VQQTVGTKGPP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.43|      12|     234|      84|      95|       9
---------------------------------------------------------------------------
   84-   95 (23.19/15.36)	QQRQSPTQVIPL
  329-  340 (23.24/15.41)	QHFSSPELVIPL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP20613 with Med6 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) FVQQKSGEKPVPVDQTKKEAEPIPETVKSEEKETTKNVQQTVGTKGPPEKRMRLH
192
246










Molecular Recognition Features






MoRF SequenceStartStop




NANANA