<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP20579

Description mediator of RNA polymerase II transcription subunit 12-like protein-like
SequenceMPANSNLRWDPDFMMDFIENPSARSINYSMLGKILSDNAANRYSFVCNTLMNVCMGHQDAGRINDIANFSSELTACCTVLSSEWLGVLKALCCSSNHVWGFNDVLCTVDVSDLSFHDSLATFIAILIARQCFSLEDVVQHVALPSLLAAACGDADAEPGARMTCRLLLHLFRAPQACLLPQATGKPFPGIRSSCDRHLLAAAHNSIEVGAVFAVLKAIMMLGDAKIGNNNVSSLKNDDFTMRGLRRDGNADDIWTASQNSKSCGKSISIETANLREYARYVLRTICQQEWVGEHCLKEPERLCTDKELILDPVLSNMQAQKLLQLICYPHGIKECTEGDNLQRQHIKRILQNLEQWTLRQSWLELQLMIKQCLKDPGSGSVAEMNNLLDNIAKATIEVFQQSADLNNNSSNSGMGLFNPNGIGNTDTSSTRQNGIKTFLSSSERRGVWLVAPLIARLPTSVQGRVLKAAGEELEKGQHLGSSSKKERDRQKQKRSPGMLARLPVGLTVHTVSTAKRQSEVAFLSNFGNEINGAWDLLNIDVICALKTMPQGYTMYGTQMPLQQTPQQQAGGVVLSPNYNSRTYPAAHSNPALMERLRQMQQPPSGYVQQQASPYLQSLTGSQR
Length623
PositionKinase
OrganismLeptonychotes weddellii (Weddell seal) (Otaria weddellii)
KingdomMetazoa
Lineage
Aromaticity0.06
Grand average of hydropathy-0.253
Instability index54.25
Isoelectric point7.78
Molecular weight68696.69
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP20579
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.31|      13|      27|     158|     173|       1
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  158-  173 (22.65/22.09)	PGARMTC.RlllHLFRA
  188-  201 (21.66/12.40)	PGIRSSCdR...HLLAA
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      77.37|      27|      35|     303|     337|       2
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  303-  335 (36.72/40.80)	CTDKeliLDPVLSNMQA....QKLLQLicyPHGIKEC
  342-  372 (40.65/20.49)	QRQH...IKRILQNLEQwtlrQSWLEL...QLMIKQC
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP20579 with Med12 domain of Kingdom Metazoa
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