<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP20577

Description mediator of RNA polymerase II transcription subunit 24
SequenceMKFHTYFKVQLCDTCLNFVFLLSLQMVSYSSVLTAISKFDDFSRDLCVQALLDIMDMFCDRLSCHGKAEECIGLCRALLSALHWLLRCTAASAERLREGLEAGAPAPAAREKQLAMCLLRLEKTLSSTKNRALLHIAKLEEASSWTAIEHSLLKLGEILASLSNPQLRSQAEQCGTLIRSIPTMLAVHSEQLHKTGYPTVHAVVLLEGTMNLTGETQPLVEQLMMVKRMQHIPTPLFVLEIWKACFVGLIESPEGTEELKWTAFTFLKIPQVLVKLKKYCHGDKDFTEDVSCAFEFLLKLTPLLDKADQRCNCDCTKFLLQECSKQGLLSEASVTNLMAKRAADREHAPQLKSGENANIQPNPGLILRAEPTVTNILKTMDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFINLNEFTTHGNEELAKAASVRALLFDISFLMLCHVAQTYGSEVILSESSTGAQVPFFETWMQTCMPEEGKILNPDHPCFWPDSTKVESLVALLNNSSEMKLVQMKWHEACLSISAAILEILNAWENGVLAFESIQKITDNIKGKVCSLAVCAVAWLVAHVRMLGLDEREKSLQMIRQLAGPLYSENTLQFYNERVVIMSSILEHMCADVLQQTATQIKFPSTGVDTMPYWNLLPPKRPIKEVLTDIFAKVLEKGWVDSRSIHIFDTLLHMGGVYWFCNNLIKELLKETRKEHTLRAVELLYSIFCLDMQQVTLVLLGHILPGLLTDSSKWHSLMDPPGTALAKLAVWCALSSYSSHKGQASSRQKKRHREDIEDYISLFPLDDMQPSKLMRLLSSNEEDANILSSPTDRSMSSSLSASQLHTVNMRDPLNRVLANLFLLISSILGSRTAGPHTQFVQWFMEECVDCLEQGSRGSILQFMPFTTVSELVKVSAMSSPKVVLAITDLSLSLGRQVAAKAIAAL
Length945
PositionTail
OrganismLeptonychotes weddellii (Weddell seal) (Otaria weddellii)
KingdomMetazoa
Lineage
Aromaticity0.07
Grand average of hydropathy0.068
Instability index46.37
Isoelectric point6.35
Molecular weight105193.43
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP20577
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      98.37|      31|      32|     100|     130|       1
---------------------------------------------------------------------------
  100-  130 (49.71/32.63)	LEAGAPAPAAREKQLAMCLLRLEKTLSSTKN
  134-  164 (48.66/31.77)	LHIAKLEEASSWTAIEHSLLKLGEILASLSN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     437.82|     143|     194|     503|     671|       2
---------------------------------------------------------------------------
  503-  671 (216.77/217.85)	FWPDSTKVESLVALLNNSSEMKLVQMKWHEACLSISAAILEILNAWENGVLAFES.IQKITDNIKGKVCSLAV.CAVAWLVAH...................VRMLGLDEREKSlQMIRQLAGPLYSENTLQFYNERVviMSSilehmcadvlqqtatqikfpSTGVDTMPYWNLlppKRPIKEVLTDIF
  698-  861 (221.05/163.02)	YWFCNNLIKELLKETRKEHTLRAVELLYSIFCLDMQQVTLVLLGHILPGLLTDSSkWHSLMDPPGTALAKLAVwCALSSYSSHkgqassrqkkrhrediedyISLFPLDDMQPS.KLMRLLSSNEEDANILSSPTDRS..MSS....................SLSASQLHTVNM...RDPLNRVLANLF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     176.79|      49|     115|     220|     273|       3
---------------------------------------------------------------------------
  220-  273 (78.24/64.32)	VEQLmMVKRM...QHIPTplfvLEIWKACFV....GLI..ESPEGTEELKWTAFTF.LKIPQVL
  275-  304 (34.41/16.22)	.......................KLKKYCH.....G.....DKDFTEDVS.CAFEFlLKLTPLL
  334-  391 (64.15/39.31)	VTNL.MAKRAadrEHAPQ....LKSGENANIqpnpGLIlrAEPTVTNILKTMDADH.SKSPEGL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP20577 with Med24 domain of Kingdom Metazoa
Unable to open file!