<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP20575

Description THAP domain-containing protein 11-like
SequenceMPGFTCCVPGCYNNSHRDKALHFYTFPKDAELRRLWLKNVSRAGVSGCFSTFQPTTGHRLCSVHFQGGRKTYTVRVPTIFPLRGVNERKVARRPAGAAAARRRQQQQQQQQQQQQQQQQQQQQQQQQQQQPQQQQQQQQQPSASTAQASQLQPNLVSASAAVLLTLQAAVDSSQAPGSVPPAPTTPTGEDVKPIDLTVQVEFAAAEGAAAAAAASELEAATAGLEAAECPMGPQLVVVGEEGFPDTGSDHSYSLSSGTTEEELLRKLNEQRDILALMEVKMKEMKGSIRHLRLTEAKLREELREKDRLLAMAVIRKKHGM
Length320
PositionMiddle
OrganismLeptonychotes weddellii (Weddell seal) (Otaria weddellii)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Laurasiatheria> Carnivora> Caniformia> Phocidae> Leptonychotes.
Aromaticity0.04
Grand average of hydropathy-0.643
Instability index67.01
Isoelectric point9.05
Molecular weight35188.28
Publications

Function

Annotated function
GO - Cellular Component
GO - Biological Function
DNA binding	GO:0003677	IEA:UniProtKB-UniRule
metal ion binding	GO:0046872	IEA:UniProtKB-KW
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP20575
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      93.63|      25|      25|     104|     128|       1
---------------------------------------------------------------------------
  103-  127 (47.80/17.33)	RQQQQQQQQQQQQQQQQQQQQQQQQ
  128-  152 (45.84/16.36)	QQQPQQQQQQQQQPSASTAQASQLQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      75.44|      24|      34|     259|     282|       2
---------------------------------------------------------------------------
  259-  282 (38.20/32.28)	TEEELLRKLNEQRDILALMEVKMK
  294-  317 (37.24/31.28)	TEAKLREELREKDRLLAMAVIRKK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.24|      17|      29|     164|     182|       3
---------------------------------------------------------------------------
  164-  182 (25.42/18.67)	LTLQaaVDSSQAPGSVPPA
  196-  212 (26.82/13.82)	LTVQ..VEFAAAEGAAAAA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.63|      16|      39|       8|      23|       5
---------------------------------------------------------------------------
    8-   23 (32.92/23.46)	VPGCYN.....NSHRDKALHF
   45-   65 (26.71/17.89)	VSGCFStfqptTGHRLCSVHF
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP20575 with Med4 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) AVDSSQAPGSVPPAPTTPTGEDVKPIDLTVQ
2) RGVNERKVARRPAGAAAARRRQQQQQQQQQQQQQQQQQQQQQQQQQQQPQQQQQQQQQPSASTAQASQLQ
169
83
199
152

Molecular Recognition Features

MoRF SequenceStartStop
NANANA