<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP20478

Description mediator of RNA polymerase II transcription subunit 24 isoform X3
SequenceMKVVNLKQAILQAWKERWSDYQWAINMKKFFPKGATWDILNLAEALLEQAMIGPSPNPLILSYLKYAISSQFDDFSRDLCVQALLDIMDMFCDRLSCHGKAEECIGLCRALLSALHWLLRCTAASAERLREGLEAGAPAPAAGEKQLAMCLLRLEKTLSSTKNRALLHIAKLEEASSWTAIEHSLLKLGEILASLSNPQLRSQAEQCGTLIRSIPTMLAVHSEQLHKTGYPTVHAVVLLEGTMNLTGETQPLVEQLMMVKRMQHIPTPLFVLEIWKACFVGLIESPEGTEELKWTAFTFLKIPQVLVKLKKYCHGDKDFTEDVSCAFEFLLKLTPLLDKADQRCNCDCTKFLLQECSKQGLLSEASVTNLMAKRAADREHAPQLKSGENANIQPNPGLILRAEPTVTNILKTMDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFINLNEFTTHGNEELAKAASVRALLFDISFLMLCHVAQTYGSEVILSESSTGAQVPFFETWMQTCMPEEGKILNPDHPCFWPDSTKVESLVALLNNSSEMKLVQMKWHEACLSISAAILEILNAWENGVLAFESIQKITDNIKGKVCSLAVCAVAWLVAHVRMLGLDEREKSLQMIRQLAGPLYSENTLQFYNERVVIMSSILEHMCADVLQQTATQIKFPSTGVDTMPYWNLLPPKRPIKEVLTDIFAKVLEKGWVDSRSIHIFDTLLHMGGVYWFCNNLIKELLKETRKEHTLRAVELLYSVFCLDMQQVTLVLLGHILPGLLTDSSKWHSLMDPPGTALAKLAVWCALSSYSSHKGQASSRQKKRHREDIEDYISLFPLDDMQPSKLMRLLSSNEEDANILSSPTDRSMSSSLSASQLHTVNMRDPLNRVLANLFLLISSILGSRTAGPHTQFVQWFMEECVDCLEQGSRGSILQFMPFTTVSELVKVSAMSSPKVVLAITDLSLSLGRQVAAKAIAAL
Length978
PositionTail
OrganismOdobenus rosmarus divergens (Pacific walrus)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Laurasiatheria> Carnivora> Caniformia> Odobenidae> Odobenus.
Aromaticity0.07
Grand average of hydropathy0.036
Instability index47.35
Isoelectric point6.34
Molecular weight108884.60
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP20478
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      98.70|      31|      32|     133|     163|       1
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  133-  163 (49.97/30.24)	LEAGAPAPAAGEKQLAMCLLRLEKTLSSTKN
  167-  197 (48.74/29.31)	LHIAKLEEASSWTAIEHSLLKLGEILASLSN
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     437.71|     143|     194|     536|     704|       2
---------------------------------------------------------------------------
  536-  704 (216.77/166.36)	FWPDSTKVESLVALLNNSSEMKLVQMKWHEACLSISAAILEILNAWENGVLAFES.IQKITDNIKGKVCSLAV.CAVAWLVAH...................VRMLGLDEREKSlQMIRQLAGPLYSENTLQFYNERVviMSSilehmcadvlqqtatqikfpSTGVDTMPYWNLlppKRPIKEVLTDIF
  731-  894 (220.94/124.34)	YWFCNNLIKELLKETRKEHTLRAVELLYSVFCLDMQQVTLVLLGHILPGLLTDSSkWHSLMDPPGTALAKLAVwCALSSYSSHkgqassrqkkrhrediedyISLFPLDDMQPS.KLMRLLSSNEEDANILSSPTDRS..MSS....................SLSASQLHTVNM...RDPLNRVLANLF
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     210.93|      70|     243|      58|     132|       3
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   58-  132 (112.83/97.23)	PLILSYL.KYAISSQfdDFSRDL.C.......VQALLDIMDMFCDrLSC.HGKAEECIGlcRALLS..ALHWLLRCTAAS...AERLREG
  303-  387 (98.10/66.78)	PQVLVKLkKYCHGDK..DFTEDVsCafefllkLTPLLDKADQRCN.CDCtKFLLQECSK..QGLLSeaSVTNLMAKRAADrehAPQLKSG
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      40.06|      13|     115|     281|     293|       4
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  281-  293 (23.61/18.53)	GLI..ESPEGTEELK
  397-  411 (16.45/10.14)	GLIlrAEPTVTNILK
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP20478 with Med24 domain of Kingdom Metazoa
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