<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP20457

Description Mediator of RNA polymerase II transcription subunit 25
SequenceMAHNKKQLVLVVEGTAALGPHWRTILSDYLLKAIRSFCGNEAMEAASPDVELALVVFNTHGSYSPFLVQRSGWTRSVDYFLEWLSAINFSGGGFREAAIAEGLAEVLMMCPSPIESQTQQNEGLLRHCILVAASNPYPLPTPVYRPPNKTETHQKIHLFDAEEVAKSFPQSCVSLSVICPRQLPKLKAIYNAGKRNPSAADPTVEVVKNQHHLVLISENFREACAALCALGVTNSPLNQTPEKSASEPPPTSVSPVIASLLNQQSAVRNISPATIKAEPRSPQTLQHVPREQVLSVQTSLPLSTSQEVTSNNDNMKIDVKPLVSVRQQPTCPPAGPENVSIPSNLSQARATNPTALAGGTTAGISSTGGNEISGGTALSVPVSQALTSSGQSNTSMGGSTPLAGTAQATQNTGTIMATMSQQVKQMQSSGVSSSMATTVGTRPQQTSSAQKSSRSSYVKVWEGELYGLRQGQPVLITRLEAYQNSTAPKPEYAGKAEYIIFRAMNQHGFLNQLQEKKLTLLLSVTDKPSRLMGMLFPGVSCVVGTGMNQVSPSQQQQQKQMAGTGMNRVSPSQEQQQQKQVVGTGMNQVSPSQQQQQKQMAGTGMKQVSPSKQQQQQKQVVGTGMNQVSPSQQQQQKQMAGTGMNQVSSPSPKP
Length654
PositionUnknown
OrganismArtemisia annua (Sweet wormwood)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> campanulids> Asterales> Asteraceae> Asteroideae> Anthemideae> Artemisiinae> Artemisia.
Aromaticity0.04
Grand average of hydropathy-0.396
Instability index58.00
Isoelectric point9.31
Molecular weight70008.55
Publications
PubMed=29703587

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP20457
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     200.91|      17|      18|     544|     560|       1
---------------------------------------------------------------------------
  544-  554 (21.90/ 6.25)	........GTGMNQV.SPS.Q
  555-  573 (36.78/14.69)	QQQQKQmaGTGMNRV.SPS.Q
  575-  593 (38.31/15.56)	QQQQKQvvGTGMNQV.SPS.Q
  594-  613 (32.10/12.04)	QQQQKQmaGTGMKQV.SPSkQ
  614-  632 (38.31/15.56)	QQQQKQvvGTGMNQV.SPS.Q
  633-  652 (33.51/12.84)	QQQQKQmaGTGMNQVsSPS.P
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     122.49|      36|      38|     335|     370|       2
---------------------------------------------------------------------------
  250-  335 (24.03/ 6.63)	PTSVSpvIASLLNQQ.savRNISPatikaeprspqtlqhvpreqvlsvqTSLPLST.SQEVTSNNDNmkidvkplvsvrqqptcppaG
  336-  374 (58.27/25.00)	PENVS..IPSNLSQA....RATNP.........................TALAGGT.TAGISSTGGN.................eisG
  375-  413 (40.19/15.30)	GTALS..VP..VSQAltssGQSN..........................TSMGGSTpLAGTAQATQN...................tG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.10|      11|      37|     441|     451|       3
---------------------------------------------------------------------------
  418-  428 (19.24/10.01)	TMSQQVKQMQS
  441-  451 (18.85/ 9.65)	TRPQQTSSAQK
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP20457 with Med25 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GMNQVSPSQQQQQKQMAGTGMNRVSPSQEQQQQKQVVGTGMNQVSPSQQQQQKQMAGTGMKQVSPSKQQQQQKQVVGTGMNQVSPSQQQQQKQMAGTGMNQVSSPSPKP
2) RNISPATIKAEPRSPQTLQHVPREQVLSVQTSLPLSTSQEVTSNNDNMKIDVKPLVSVRQQPTCPPAGPENVSIPSNLSQARATNPTALAGGTTAGISSTGGNEISGGTALSVPVSQALTSSGQSNTSMGGSTPLAGTAQATQNTGTIMATMSQQVKQMQSSGVSSSMATTVGTRPQQTSSAQKSS
546
268
654
453










Molecular Recognition Features






MoRF SequenceStartStop




1) KQVSPS
2) QKQVVGTGMNQV
606
617
611
628