<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP20454

Description Leucine-rich repeat protein kinase family protein
SequenceMARTSYFSQISVVLLAILFVRIRCSKPHNASQEQTLLSIQQLLYYPVVLSSWNNATDFCNTVQSSSVTVICYEDVVTQLHIINSDKAPPLPKDFSIDTLFTTLDSLPSLKVLTLASLGLWGKLPATISNLSSLEILNLTSNHFYGSIPPEITSLTDLQSLVLDDNKFTGWIPSRVGFLSRLSVLSMKNNSLNGLLPKSLGSLVDLRVLMLSHNNFTGQVPDLSSLTNLQVFEIEDNSLGPSFPQVTNRITSIVLRDNKFTAGLPEEIHSFYQLRKLDIALNRFVGPFPTSILSLPSITYLDIEGNKFTGMLFEDLSCNPKLQFVDLSANLLTGKLPSCLVSSVARNVVYDGNCLNVNDVNEVKVKSQNPVSFCRNQALAVGVIPRHHMSGKKSNVGLIFGIIGGILGGIILVGVALFVFSHVYGKKMVKKPPPRVIAENGPGSYTSKLLSDARYVTRVMKLGSLGIPAYRTFLLEELEEATNGFDTSTFMGEGSHGQSQVLKNFGSKFKFLISTGVNQIINLVVLMDNWRDMIDQTVMSCEEKKLVKEVLRIKAFLDEKVGDDECGSWVAYQSLRKLQQMVLSVKVLKETMIGESVGVYLKHASKDVSRVSRFLMNEWRCVVDEWVEANEKKTSLDQKEMKKDVKITEPQRPRVVRIKLKTKSESDNDNVVPKGPITHEKKVGNNNGIDEVLRIKGVIKKSIGDESESQSTLLDSLKKLQHMDISMETLDKTGIGKTVNAFKKHVSKDVSHLARTLVKAWKDMAEEWIKKDMINVKPISEQAKNHKGLVTHGQHCQPIDSDATTSDQKSLVVHGQHSRPIDSDAATSDHKGLSNTTEEKMESTKKKLEERYKELENMKQKRKIQVIEHYELPRNSRLPPKAQHVKPVNERVKR
Length893
PositionUnknown
OrganismArtemisia annua (Sweet wormwood)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> campanulids> Asterales> Asteraceae> Asteroideae> Anthemideae> Artemisiinae> Artemisia.
Aromaticity0.06
Grand average of hydropathy-0.233
Instability index34.66
Isoelectric point9.08
Molecular weight99740.95
Publications
PubMed=29703587

Function

Annotated function 
GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
kinase activity	GO:0016301	IEA:UniProtKB-KW

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP20454
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     165.99|      30|      30|     544|     573|       1
---------------------------------------------------------------------------
  544-  573 (45.46/29.48)	KLVKEVLRIKAFLDEKVGDDECGSWVAYQS
  576-  604 (45.65/29.63)	KLQQMVLSVKVLKETMIG.ESVGVYLKHAS
  690-  715 (30.90/17.71)	....EVLRIKGVIKKSIGDESESQSTLLDS
  718-  746 (43.99/28.29)	KLQHMDISMETLDKTGIG.KTVNAFKKHVS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             9|     241.37|      19|      21|     106|     124|       2
---------------------------------------------------------------------------
  106-  124 (29.06/16.36)	LPSLKVLTLASLGLWGKLP
  130-  148 (28.24/15.68)	LSSLEILNLTSNHFYGSIP
  157-  172 (22.46/10.87)	LQSL.VLDDNKFTGW..IP
  178-  196 (25.07/13.04)	LSRLSVLSMKNNSLNGLLP
  202-  220 (28.60/15.98)	LVDLRVLMLSHNNFTGQVP
  225-  243 (25.94/13.77)	LTNLQVFEIEDNSLGPSFP
  270-  288 (26.84/14.52)	FYQLRKLDIALNRFVGPFP
  294-  312 (28.44/15.84)	LPSITYLDIEGNKFTGMLF
  318-  336 (26.73/14.43)	NPKLQFVDLSANLLTGKLP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     245.12|      77|     139|     605|     688|       3
---------------------------------------------------------------------------
  605-  688 (123.58/102.87)	KDVSRVSRFLMNEWRCVVDEWVeaneKKTSLDQKEMKKDVK.....ITEPQRPRVVRiklKTKSESDNDNVVPKG....PITHEKKVGNNNGI
  747-  832 (121.54/84.78)	KDVSHLARTLVKAWKDMAEEWI....KKDMINVKPISEQAKnhkglVTHGQHCQPID...SDATTSDQKSLVVHGqhsrPIDSDAATSDHKGL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.30|      15|      15|     850|     864|       4
---------------------------------------------------------------------------
  850-  864 (25.08/17.98)	RYKELENMKQKRKIQ
  868-  882 (27.22/20.21)	HYELPRNSRLPPKAQ
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP20454 with Med26 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ISEQAKNHKGLVTHGQHCQPIDSDATTSDQKSLVVHGQHSRPIDSDAATSDHKGLSNTTEEKMESTKKKLEERYKELENMKQ
2) RKIQVIEHYELPRNSRLPPKAQHVKPVNERVKR
778
861
859
893










Molecular Recognition Features






MoRF SequenceStartStop




1) KAQHVKP
2) KRKIQVIEHYELPRNSRLP
880
860
886
878