<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP20453

Description U-box domain-containing protein kinase family protein
SequenceMHKLLNQYKQICQKAGVCPEVHYIEMSSIEKGIVALILEHNVRRLVMGAAADKHYSRKMVDLRSRTAIYVRLQADPSCQIQFICKDKLIFTRQGRLDGPVSAPPLSLPANTNTNSGQGSTRSRSVSEGQNIIFQPNNPTQEYRRVMSYTPGTRISTSSSTLSPNFNAELHSAGRLNSGRGYDDWSLISHKSPSTNSRMSTGSTDVLDDSGRTPYAISEGNEVDSDAGAVPGSKEIIENPSPSSVIERGMNDELYVQLLEAMAEADNSKRDAFDESIRRRKAEKDAIEAKRRVKTAENMYAEELRRRLEIDETLEKINEEHNIMKKQLDEITEELRLALEQKSFLESQSAALDHTVQDLEHKMFSAVELLQNYKKERDELQVECDDALRLVEELREKQSKEASSSSVSQFYTEFDFSEVRDATRNFDPSLKIGEGGYGSIFRGFLRHTEVAIKVLHSHSMQGPSEFQQEVNVLSKLRHPNLVTLIGACPDAWIIIYEYLSGGSLEDRLDCKDNTPPLSWQNRIRIAAELCSVLIFLHSCGIVHGDLKPANLLLDKNLVSKLSDFGICRVLSPNEFSSNNTSLCCRTDPKGTFAYMDPEFLTTGELTSKSDTYSFGVILLRLLTGKPAMKLRKEVQDAINEGNLKNMLDPTAGDWPFVQAQQLVLLAMDCCDVRKNRPDLASVAWRVLEPMRVSCGLSSSRFGLEGQCQIPHYFICPIFQEIMQDPMVAADGFTYEGEALRGWLDSGNNTSPMTNLELANSNLVPNHALRSAIQEWLQQP
Length778
PositionTail
OrganismArtemisia annua (Sweet wormwood)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> campanulids> Asterales> Asteraceae> Asteroideae> Anthemideae> Artemisiinae> Artemisia.
Aromaticity0.07
Grand average of hydropathy-0.450
Instability index53.72
Isoelectric point5.51
Molecular weight87237.63
Publications
PubMed=29703587

Function

Annotated function Functions as an E3 ubiquitin ligase. 
ECO:0000256	ARBA:ARBA00003861
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP20453
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      63.79|      21|      78|      94|     125|       1
---------------------------------------------------------------------------
   94-  118 (33.32/36.44)	GRldgpVSAPPLSLPANTNT........NSGQG
  152-  180 (30.47/10.27)	TR....ISTSSSTLSPNFNAelhsagrlNSGRG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.14|      14|      19|     301|     319|       2
---------------------------------------------------------------------------
  301-  314 (23.75/25.10)	EELRRRLEIDETLE
  332-  345 (23.39/ 9.98)	EELRLALEQKSFLE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      80.67|      19|      19|     192|     210|       3
---------------------------------------------------------------------------
  192-  210 (33.98/20.79)	PSTNSRMSTGSTDVLDDSG
  213-  227 (26.09/14.32)	PYA...ISEGN.EVDSDAG
  239-  253 (20.60/ 9.80)	PSPSSVIERGMNDEL....
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP20453 with Med32 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GYDDWSLISHKSPSTNSRMSTGSTDVLDDSGRTPYAISEGNEVDSDAGAVPGSKEIIENPSPSSVIERGM
2) VSAPPLSLPANTNTNSGQGSTRSRSVSEGQNIIFQPNNPTQEYRRVMSYTPGTRISTSSSTLSPNFNAELHSAG
180
100
249
173










Molecular Recognition Features






MoRF SequenceStartStop




NANANA