<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP20451

Description U-box domain-containing protein kinase family protein
SequenceMEGAQRMNQIRYPVIDTSEIMEIRTDIVETIPPNPRAEEDNIYVAVGKEVKESQLALRWALDNLGGWGILYTHQIVAHRAAEMQEMNQILDKYKQICQKAGVFAEVHYIEMNSIEKGIVDFILKHNVRKLAMGAAADKQFSKRMVDVRSKKAVYVKLKAAAFCQIQFICKGNVIFTRQGTLDGVGFSTASPSASPNTTSGTDNRRVMSNNRGTELPAXRQFRRFIEGGILYTHQIVAHRAAEMQEMNQILDKYKQICQKAGVFAEVHYIEMNSIEKGIVDFILKHNVRKLAMGAAADKQFSKRMVDVRSKKAVYVKLKAAAFCQIQFICKGNVIFTRQGTLDGVGFSTASPSASPNTTSGTDNRRVMSNNRGTELPAFSSPSFNTDSTSTSRLTSGRAFDEWSGISRSTNSRFSSCSSELADDLGQTPYSISEVNEVQSDYGAVTVFIEEIPNHPPSSVMERGMNDELYDQLEQAMAEVDTSKREAFEESIRRRKAEKDAMDARRKVKALENMYGEELRRRQEIDETLTKTKEENENIKKEHNEVVEELRVALEQKSYLQSQITDLNHTVQEVEQKMFSAIELLKHYKGERDEMQVECDHALQLVEELSSKQTGEASSSGVSQFYNEFSLTEIQDATRNFDQSLKIGEGGYGSIFRGFLRHTEVAIKMLHSHSLQGPSEFQQEVNVLSKLRHPNLVTLIGVCPDAWTIVYEYLPGGSLEDRLGCKDNTPPLSWQNRIRIAAELCSVIIFLHSCGIIHGDLKPDNLLLDKNLVTKVSDFGICRVLSGQEFSDNNTSICRTGPKGTFLYMDPEFLSTGELTSKSDTYSFGVILLRLLTGKPALGLTKEVKCALNEKKLKNILDPAAGDWPFVQAQQLAVLAMNCCDMIRQNRPDLVSEVWRVLEPMAVSCGLSSFRVGSEGQSEIPHYFVCPIFQKTMQDPVIAADRFTYEAEAIKGWLDSGHNTSPMTNLELANHALHSAIQEWLQKP
Length987
PositionTail
OrganismArtemisia annua (Sweet wormwood)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> campanulids> Asterales> Asteraceae> Asteroideae> Anthemideae> Artemisiinae> Artemisia.
Aromaticity0.07
Grand average of hydropathy-0.386
Instability index44.81
Isoelectric point6.04
Molecular weight110641.45
Publications
PubMed=29703587

Function

Annotated function Functions as an E3 ubiquitin ligase. 
ECO:0000256	ARBA:ARBA00003861
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP20451
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     650.63|     158|     159|      58|     216|       1
---------------------------------------------------------------------------
   51-  210 (321.36/210.09)	KESQLA.lRWALDNLGGwGILYTHQIVAHRAAEMQEMNQILDKYKQICQKAGVFAEVHYIEMNSIEKGIVDFILKHNVRKLAMGAAADKQFSKRMVDVRSKKAVYVKLKAAAFCQIQFICKGNVIFTRQGTLDGVGFSTASPSASPNTTSGTDNRRVMSNN
  211-  370 (329.27/209.92)	RGTELPaxRQFRRFIEG.GILYTHQIVAHRAAEMQEMNQILDKYKQICQKAGVFAEVHYIEMNSIEKGIVDFILKHNVRKLAMGAAADKQFSKRMVDVRSKKAVYVKLKAAAFCQIQFICKGNVIFTRQGTLDGVGFSTASPSASPNTTSGTDNRRVMSNN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      69.70|      24|      57|     526|     549|       3
---------------------------------------------------------------------------
  526-  549 (39.07/31.37)	ETLTKTKEENENIKKE..HN.EVVEEL
  582-  608 (30.63/22.75)	ELLKHYKGERDEMQVEcdHAlQLVEEL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      71.29|      17|      46|     419|     435|       4
---------------------------------------------------------------------------
  419-  435 (28.72/15.47)	ELADDLGQTPYSISEVN
  447-  461 (20.04/ 8.88)	FIEEIPNHPPSSVME..
  467-  480 (22.54/10.78)	ELYDQLEQ...AMAEVD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      25.14|       8|      18|     554|     563|       6
---------------------------------------------------------------------------
  554-  563 (10.16/12.84)	EQKSYlqSQI
  574-  581 (14.98/ 9.11)	EQKMF..SAI
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP20451 with Med32 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) FSTASPSASPNTTSGTDNRRVMSNNRGTELPAFSSPSFNTDS
2) GAVTVFIEEIPNHPPSSVMERGMNDELYDQLEQAMAEVDTSKREAFEESIRRRK
346
442
387
495










Molecular Recognition Features






MoRF SequenceStartStop




NANANA