<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP20448

Description "Zinc finger, RING/FYVE/PHD-type"
SequenceMKLLQPSDSMPAETLSGFCSPASFRDGFHRKSVPLAEDDGGDKVYVAVGKSVEKVVSLLRWTFRRFRGCEICLLHVHQPSPFIPTLLGKLPATQANPDVVRAYRREERYQMQKLLLDYISLCSRSKVKACVVTTENDQVRKGIVDLLNEYGVQKLVMGAVPENWMTVKKGSSKSSYAAKNAPPFCHIWFVNNSQLLYTREPAEDYDSLPPLIPQASNALRSQSLRYPNTQRELQQIYSRSSSSINLIGGSTSMTRSTKQFHGDGLHNNLQSNTSSDSGYSSSTELDSRLEEESLSKQLEEVNIEAEASRNQAFQELLKRKRLEALAIEANNKVKVYESAHAQEVELRKAAEDTLNTARVEHKQLMQQKELASKELHKAMRNIALSRNQVQEANRRREESSEELKLIEASITTLKIEQQAVQRQRLEASDWLERWKIRGQAGGVSSTTPRLMEFTLLDLETATCGFSDSFKISCESDGVSFYKGEMLKRTVMIKKLHPNNLQAQSEFQQEYQVVGRLQHKHILSLVGICQEAYALVYEYTPWSLESHLSSKTNSTCWKTRTRVISEIANALLFLHTFRPEKISHGNLKPENIVLDSELSCKLCNFRFSSFVNEETFRCRSFRQYAEQNGPFSFTDPEVVQTGTLTAKSDIYSFGMIILWLLTGSQSAGLVNEVRKAVLGSSLVSVLDASAGEWPIFVAKRLADFGLRCCESNTRDRPMISPILVKELQQLSFLEDRQVPSFFLCPILKEIMYDPQLAADGFTYEGEALRGWLKNGNETSPMTNLKLSHLDLIPNHSIRVAIQDWLCNPSSM
Length810
PositionTail
OrganismArtemisia annua (Sweet wormwood)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> campanulids> Asterales> Asteraceae> Asteroideae> Anthemideae> Artemisiinae> Artemisia.
Aromaticity0.08
Grand average of hydropathy-0.408
Instability index55.24
Isoelectric point8.01
Molecular weight91622.19
Publications
PubMed=29703587

Function

Annotated function Functions as an E3 ubiquitin ligase. 
ECO:0000256	ARBA:ARBA00003861
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein kinase activity	GO:0004672	IEA:InterPro
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP20448
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     148.82|      42|      89|     282|     328|       2
---------------------------------------------------------------------------
  282-  323 (65.91/40.51)	STELDSRLEEESLSK.QLEEVN............IEAEASRNQA...FQELLKRKRLE
  343-  370 (29.49/14.88)	EVELRK.............................AAEDTLNTArveHKQLMQQKEL.
  372-  426 (53.42/30.49)	SKELHKAMRNIALSRnQVQEANrrreesseelklIEASITTLKI...EQQAVQRQRLE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     153.45|      48|      89|     443|     506|       3
---------------------------------------------------------------------------
  443-  506 (74.64/76.97)	VSSTTPRLMEFTLLDLETATCG...............FSDSFKISCESDGvsfykgemlkrtvmikKLHPNNLQAQSEF
  535-  597 (78.81/50.68)	VYEYTPWSLESHLSSKTNSTCWktrtrviseianallFLHTFRPEKISHG................NLKPENIVLDSEL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     146.12|      42|     110|     629|     670|       4
---------------------------------------------------------------------------
  629-  670 (72.81/58.03)	PFSFTDP...EVVQTGTLTAKSDIYSFGMIILWLLTGSQSAGLVN
  738-  782 (73.30/58.47)	PSFFLCPilkEIMYDPQLAADGFTYEGEALRGWLKNGNETSPMTN
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP20448 with Med32 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) RSTKQFHGDGLHNNLQSNTSSDSGYSSSTELDSRLEEESLSKQLEEVNIEA
255
305










Molecular Recognition Features






MoRF SequenceStartStop




NANANA