<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP20447

Description U-box domain-containing protein kinase family protein
SequenceMEDHGIVKGVDELPTPSYLVVALAVNGSRKTKYVIKWALDKFVPEGILLFKLFFVRPKITWVPTPTVGTVPVSQVREDVVIAYKKEVEWQADQKLLPYKNMCARRKVDVDIVHIESDDIVDAIKQEIVKQKINKLVIGASSNGMFSRGRNLSSRISESIPSFCTVYAISKGKLSSLRASDSETIGSSKDDDNTSDSSSITNSSFAQTEWTDQGSASTYTQFFSNSLPMQRIEALSSINRTLHKRTSSLESTGNKLDSSEGDEALASYGSNPDYLRENSTASSSKSFLTENHSWTSDQDSIPYAPSEIASEIQDNNMSFELEKLRVELRHIRGMYAMAQSETFDASRRLNDLQKQQLEESIKLKELKVKEEESKALAEQQKKEHEAAKRQAEYVKECVRREAAVRLDAEERALQESKEKQKLQKAITGTSQKFENFTWDEIVAACSSFNEDLKIGAGGNGTVYKSSFHHTVAAVKVPHSQEAHRTKQFQQELEVLSRIRHPHLLILIGACVDRGCLVYEYMENGSLDERLFRINNTPPIPWFDRFRIAWEVASALIFLHNTKPKSIVHRDLKPANILLDRNLVSKIGDVGVSTMLQSDPCSTSTVYKDTTPAGTYCYIDPEYQRTGLVSPKSDVYALGMVILQLLTAKPAIGLTYVVETAIEDDELATVLDLEAGEWPVDEAKELANLGLSCAELRRKDRPDLKTVVLPTLERLKAVADEAQRTTSMARTTPPNHFICPILKDVMIDPCVAADGYTYDRRAIEKWFEESDNSPMTNLPLTSRSLTPNYTLFSAIMEWKSRT
Length800
PositionTail
OrganismArtemisia annua (Sweet wormwood)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> campanulids> Asterales> Asteraceae> Asteroideae> Anthemideae> Artemisiinae> Artemisia.
Aromaticity0.07
Grand average of hydropathy-0.431
Instability index43.08
Isoelectric point5.77
Molecular weight89817.61
Publications
PubMed=29703587

Function

Annotated function Functions as an E3 ubiquitin ligase.
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP20447
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     114.44|      38|      64|     156|     195|       2
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  156-  195 (55.35/45.43)	SESIPsFCTVYAISK.GKLSSLRASDSETIGsSKDDDNTSD
  223-  261 (59.08/38.83)	SNSLP.MQRIEALSSiNRTLHKRTSSLESTG.NKLDSSEGD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.49|      18|     313|     126|     143|       5
---------------------------------------------------------------------------
  126-  143 (31.29/24.80)	EIVK..QKINK.LVIGASSNG
  439-  459 (23.19/16.38)	EIVAacSSFNEdLKIGAGGNG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.25|      10|     197|      89|      98|       6
---------------------------------------------------------------------------
   89-   98 (20.87/11.63)	WQADQKLLPY
  293-  302 (21.38/12.07)	WTSDQDSIPY
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP20447 with Med32 domain of Kingdom Viridiplantae

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