<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP20445

Description U-box domain-containing protein kinase family protein
SequenceMESTSMVVAVGVKGGNTGGLGGKGSRRAVKWAVENLLLPDHDHDYCLVLVHVIPNITSVPTPSGKQVPVTELDANVVAMYVKDYKSQIEEVFIPFKKLCKGKKIETLVVEGDNPASGLVNYVSESGINSLVLGFSSSNLLTRTFYGAGVPAAVLKRAPRSCNIYVVSRDGLISNSDISSTSLGSCGMSKLWCGLGSSSKFKIESTIEQSSVSDMTRLNSQASNHEKAFVSSSTTEMSNSSRRTLGDARLQTRVPTRSSVSSTCSDQSNLQTEVEKLRLELRDAVNMYNQACDELVHTQTKVQMLSFDSLEDAKRINSAVEREEKFRKIAAEEKEKHLEAIKEVETARNLLAIEAYEREIAELKAMQESSEKQQIVDALFTSDKRYRRYTIDEIEVATESFSKSKVVGEGAYGKVYKCNLDHTPVAIKVLWSDTSEKKREFLREVEVLSQLSHPHMVQLLGACPERGCLIYEYMENGSLEEYVSKKNTKYYLSWYTRFRIAFEVACALAFLHNSKPDPIVHRDLKPGNILLDRNFVSKIGDVGMAKLITDVVPDNVTEYKDSILAGTMYYIDPEYHRTGTIRPKSDLYAFGIIVLQLLTLLQPKAAISKVESAVSSGRLSDVLDDSINDWPLAEAEELAKLALKCCSLRCRDRPDLDTEVLPVLKKLHEFGDTSRKVGKISNDAPSHFYCPITQEIMDDPYIAADGFTYEHRAIKIWIERQNVSPVTKRRLQHKTLTPNHTLRSAIQDWRLRSSTSK
Length756
PositionTail
OrganismArtemisia annua (Sweet wormwood)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> campanulids> Asterales> Asteraceae> Asteroideae> Anthemideae> Artemisiinae> Artemisia.
Aromaticity0.07
Grand average of hydropathy-0.334
Instability index48.97
Isoelectric point6.99
Molecular weight84476.28
Publications
PubMed=29703587

Function

Annotated function Functions as an E3 ubiquitin ligase. 
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein serine/threonine kinase activity	GO:0004674	IEA:UniProtKB-KW
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP20445
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.58|      18|      96|     210|     228|       1
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  210-  228 (27.60/20.53)	SVSDMTRLNSQASNHEKaF
  308-  325 (29.98/17.72)	SLEDAKRINSAVEREEK.F
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      81.72|      24|      49|     122|     148|       2
---------------------------------------------------------------------------
  122-  148 (36.14/27.31)	VSESGINSLVLGfssSNLLTRTFYGAG
  172-  195 (45.58/26.31)	ISNSDISSTSLG...SCGMSKLWCGLG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      79.71|      26|      27|     248|     274|       3
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  248-  274 (38.29/30.67)	RLQTRvPTRSSVSSTCSDQSNLQTEVE
  277-  302 (41.42/28.26)	RLELR.DAVNMYNQACDELVHTQTKVQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     115.06|      29|      48|     378|     406|       5
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  355-  375 (24.78/12.70)	.......YER.EIAELKAMQESSEKQQIV
  378-  406 (46.05/29.65)	LFTSDKRYRRYTIDEIEVATESFSKSKVV
  429-  456 (44.23/28.20)	LWSDTSEKKREFLREVEVLSQ.LSHPHMV
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP20445 with Med32 domain of Kingdom Viridiplantae
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