<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP20435

Description ATP-dependent DNA helicase
SequenceMGGTEDVMQELLNVEFELQDVQDEIKRLLDKQEKLYERQSELKAVLESYQDLEKSEQDNAAPQAENWSGSFEWDNEADDIRFNIFGIPSYRANQREIINAVMSGRDVLVIMAAGGGKSLCYQLPALLRDGIALVISPLLSLIQDQVMGLTALGIPASMLTSTTNKEDEKYIYKALEKGDGDLRVLYVTPEKVSKSKRFVSKLEKCHHAGRLSLISIDEAHCCSQWGHDFRPDYKNLGILKTQFPNVPVIALTATATKKVQLDLMEMLKIPKCVKFVSTVNRPNLFYMVRDKSSVGKTVINDIADFIQGSYTNNESGIVYCFSRKECEQVAKELRERGVSADHYHADMDVNARERVHMRWSNSKLQVIVGTVAFGMGINKPDVRFVIHHSLGKSMETYYQESGRAGRDGLPSECLLYFRPADVPRQSSMVFYENSGLQNLYDMVRYCQSKKECRRGAFFKHFAEPLQDCNGMCDNCAFSCDVKEIDATGHAKAVVSLLQEIQEMDQRATMLQLVEKFKVKNKKVGFELKKDELEQLVIQLILDRVLKEEFSHTAYATNAYVTTGPLAKHVLHGKKNIMLEVTSGHKSSTSVAKSSKRSRYSGLEVELDNLRKELSSLHGGIFPHSILSTQQIGMLCSQKPETTEQLEKLIGKLKTEKYGDKILEVIGKHEPDEEQHGNDPSENEEEPETSVNRTSKRTKNKNVVVIESSEDDE
Length712
PositionUnknown
OrganismArtemisia annua (Sweet wormwood)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> campanulids> Asterales> Asteraceae> Asteroideae> Anthemideae> Artemisiinae> Artemisia.
Aromaticity0.07
Grand average of hydropathy-0.478
Instability index42.24
Isoelectric point5.96
Molecular weight80428.68
Publications
PubMed=29703587

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
3'-5' DNA helicase activity	GO:0043138	IEA:InterPro
ATP binding	GO:0005524	IEA:UniProtKB-KW
hydrolase activity	GO:0016787	IEA:UniProtKB-KW
nucleic acid binding	GO:0003676	IEA:InterPro

GO - Biological Process
DNA recombination	GO:0006310	IEA:InterPro
DNA repair	GO:0006281	IEA:InterPro
DNA replication	GO:0006260	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP20435
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      63.98|      19|     152|     283|     337|       1
---------------------------------------------------------------------------
  283-  330 (24.20/67.02)	NLFYMVRdkssvgktvindiadfiqgsytnnesgivYCFSRKECEQVA
  438-  456 (39.78/16.56)	NLYDMVR.............................YCQSKKECRRGA
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP20435 with Med34 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) KILEVIGKHEPDEEQHGNDPSENEEEPETSVNRTSKRTKNKNVVVIESSEDDE
660
712










Molecular Recognition Features






MoRF SequenceStartStop




1) EEEPET
2) KHEPDEEQHG
3) VVVIES
683
667
702
688
676
707