<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP20423

Description "Transcription elongation factor, TFIIS/CRSP70"
SequenceMSCEEKKLVKEVLRIKAFLDEKVGDDECGSWVAYQSLRKLQQMVLSVKVLKETMIGESVGVYLKHASKDVSRVSRFLMNEWRCVVDEWVEANEKKTSLDQKEMKKDVKITEPQRPRVVRIKLKTKSESDNDNVVPKGPITHEKKVGNNNGIDEVLRIKGVIKKSIGDESESQSTLLDSLKKLQHMDISIETLDKTGIGKTVNAFKKHVYKDVSQLARMLVKTWKDMAEEWIKKDISNVKPISEQAKNHKGLVTHGQHCQPIDSDATTSDQKSLVVHGQHSRPIDSDAATSDHKGLSNTTEEKMESTKKRLEERYKELENMKQKRKIQVIEHYELPRNSRLPPKAQHVKPVNERVKR
Length356
PositionUnknown
OrganismArtemisia annua (Sweet wormwood)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> campanulids> Asterales> Asteraceae> Asteroideae> Anthemideae> Artemisiinae> Artemisia.
Aromaticity0.04
Grand average of hydropathy-0.841
Instability index34.56
Isoelectric point9.35
Molecular weight40834.47
Publications
PubMed=29703587

Function

Annotated function
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell
GO - Biological Function
translation elongation factor activity	GO:0003746	IEA:UniProtKB-KW
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP20423
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     122.41|      29|      55|      14|      42|       1
---------------------------------------------------------------------------
   10-   41 (42.59/22.19)	KevlRIKAFLDEKVGDDEC..GSWV.AYQSLRKLQ
   42-   67 (19.85/ 7.26)	QmvlSVKVLKETMIG.ESV..GVYL.KHAS.....
   72-   99 (24.92/10.59)	....RVSRFL...MNEWRCvvDEWVeANEKKTSLD
  156-  183 (35.06/17.25)	....RIKGVIKKSIGDESE..SQST.LLDSLKKLQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     100.40|      20|      20|     254|     273|       2
---------------------------------------------------------------------------
  239-  251 (17.39/ 7.09)	.....KPISEQA..KNHKGL
  254-  273 (41.25/24.93)	HGQHCQPIDSDATTSDQKSL
  276-  295 (41.77/25.32)	HGQHSRPIDSDAATSDHKGL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.12|      16|      20|     312|     327|       4
---------------------------------------------------------------------------
  312-  327 (26.99/18.51)	ERYKELENMKQKRKIQ
  330-  345 (29.13/20.53)	EHYELPRNSRLPPKAQ
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP20423 with Med26 domain of Kingdom Viridiplantae

Intrinsically Disordered Regions

IDR SequenceStartStop
1) ISEQAKNHKGLVTHGQHCQPIDSDATTSDQKSLVVHGQHSRPIDSDAATSDHKGLSNTTEEKMESTKKRLEERYKELENMKQKRKIQVIEHYELPRNSRLPPKAQHVKPVNERVKR
241
356

Molecular Recognition Features

MoRF SequenceStartStop
1) KAQHVK
2) KRKIQVIEHYELPRNSRLP
343
323
348
341