<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP20422

Description "Coactivator CBP, KIX domain-containing protein"
SequenceMETLKRHLPFSGHEGLQELKKIAVRFEEKIYTAATSQSDYLRKISLKMLTMETRSQNPMPDPMQANSGLNPADPGSQVMPQVNMQGQQLPIPVPSQSGQQQMMPQNMQNNIGSTGMQGSSSLSAALPTGSGLSQSTMSNVAGQNSNLQNMQNMSTMQQGSVGNTMGANSFTNQRQIPGRQQLVPQQQQQQQQQPQQQNPNSHYLYQQQLHQMAKQKLQQNNINPAMQSQMQQQQQQQQQQQQQQQNLLQSGMQPTMMQTPSLSGVVQNQQAAVPQSSQPLLNHPQSVLRQQQRQQQVQPTQQQVQPTQSNPMGQQANATSMQQNPLIGQQSNYSDMQQQRLLGQQNKLSSVQQPQQHLIGQHNNLSGMQQQHLGSQNNASGQQQLLGSQSGNTGMQTNQHSVQQMLQSKMPIQQQNQQSSATMLPTQVQQSQPQLQQQVMPQMQSQSGQLQQQMGMQQQPNLLQRDMQQRLPTAGGFQQQNVIDQQKLYQQQRAMPEASSTSLDSTDQTRSANGVVDWQEEVYQKIKAMKDLYLHDLNDMHQKILGKLQHQPKNEQLEKLKVFKNMLERFMAFLQIPKQSILANYKDKLGTYEKQIVNVINSNRRKPGAPQQQGQALPPQHMQSQQPHSQSHDNQMSSQMQTGNMQGSMGGMQQNNMGSMQQNSVSSLQGSANPQQNMMNSMQPSSNLDQVQNSSMNSLQQVSGGSLQQNAVSGGQQVNINPMASHSGMGTLQPNSNMLQHQHIKQQEQLLQSQQLKQFQHRQMQQQYVHKQQLLQQQQQQQQQQFHQQAKQQQGGQLQGNQLGQLHQINDGGDVKLRQQMNMKSGAFQQQQATAAQRSAYHQQLKSGAPFSPQLLSAASPQMSQHASPQIDQQGMFNSHTKSGTPLQSANSPFAVPSPSTSSASPLPGPGEFERINGVSSLSNVGNIGHQQANAAVVPSQSLAIGTPGMSASPLLAEFTSPDGINGVVPSIGSGRSSVTEQPLERLIKAVKSISPAALSASVSDIGSVVSMIDRIAGSAPGNGSRAAVGEDLVAMTKCRLQARTLVSQDGTNGVRKMKRFTSAMPLNVVSSAGSVNDSFKQLSCVDSSELDSTASSAIKRPRVETNHALVEEIKEINRGLIDTVVNISEEDADPAAASEGGDGTVVKCSFSAVALGPNLKSQYASAQMSPIQPLRLLVPANYPNCSPILLDKFPAEVSKDYEDLSTKTKSRFSISLRSLSQPMSLKEIAKTWDVCARAVISDYAQQSGGGTFSSKYGTWENCLSAA
Length1267
PositionTail
OrganismArtemisia annua (Sweet wormwood)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> campanulids> Asterales> Asteraceae> Asteroideae> Anthemideae> Artemisiinae> Artemisia.
Aromaticity0.03
Grand average of hydropathy-0.792
Instability index70.19
Isoelectric point9.37
Molecular weight138881.73
Publications
PubMed=29703587

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
chromatin DNA binding	GO:0031490	IEA:InterPro
transcription coactivator activity	GO:0003713	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP20422
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             8|     430.34|      45|      45|     176|     220|       1
---------------------------------------------------------------------------
   73-  110 (51.67/11.24)	D.PG.S.Q..............VMPQVNMQGQQLP.....I................P.VPS...QsgQ.Q...QMMPQNM.QNN
  176-  220 (89.51/27.12)	I.PGRQ.Q..............LVPQQQQQQQQQP.....QQQN.............P.NSHYLYQ..Q.QLH.QMAKQKL.QQN
  222-  279 (47.40/ 9.44)	InPAMQsQ..............MQQQQQQQQQQQQ.....QQQNllqsgmqptmmqtP.SLSGVVQ..N.Q...QAAVPQS.SQP
  281-  324 (47.87/ 9.64)	L.NHPQ.S..............VLRQQQRQQQVQP.....TQQQ...........vqPtQSNPMGQ..QaNAT.SM......QQN
  379-  416 (47.07/ 9.30)	A.SGQQ.Q..............LLGSQSGNTGMQT.....NQ...................HSV.Q..Q.MLQsKMPIQ...QQN
  668-  710 (46.45/ 9.04)	L.QGSA.N................PQQNMMNSMQPssnldQVQN.............S.S.....M..N.SLQ.QVSGGSL.QQN
  712-  767 (47.03/ 9.29)	V.SGGQ.QvninpmashsgmgtLQPNSNMLQHQHI.....KQQE.................QLLQS..Q.QLK.QFQHRQM.QQQ
  768-  807 (53.33/11.93)	Y.VHKQ.Q..............LLQQQQQQQQQQF.....HQQA.............K.......Q..Q.QGG.QLQGNQLgQLH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.12|      20|      21|     455|     474|       2
---------------------------------------------------------------------------
  441-  467 (30.06/ 6.60)	PQMQSQSgqlqqqmGMQQQPNLLQRDM
  468-  488 (29.06/ 6.12)	QQRLPTA......gGFQQQNVIDQQKL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     197.23|      42|      43|     888|     929|       3
---------------------------------------------------------------------------
  850-  887 (29.69/12.03)	......PF..........SPQLL......SAA...SPqmsqhaspqidqqGM....F...N......SHTKSGTPL
  888-  929 (79.85/45.77)	QS.ANSPFA.......VPSPSTS......SASPLPGP.............GE....F...ERINGVSSLSNVGNIG
  931-  973 (46.13/23.09)	QQ.ANAA.V.......VPSQSLAigtpgmSASPL..L.............AE....FtspDGINGVVP.....SIG
  977- 1024 (41.56/20.01)	SSvTEQPLErlikavkSISPAAL......SAS.VSDI.............GSvvsmI...DRIAG....SAPGN.G
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     175.77|      53|     119|     490|     542|       5
---------------------------------------------------------------------------
  137-  175 (30.41/ 6.47)	...............MSNVAGQNSNLQNM......QNM............STMQQGSVgntmgaNSFTNQRQ.....
  514-  584 (68.43/26.58)	GVVDWQEEVYQKIKAMKDLYLHDLNDMHQkilgklQHQpkneqleklkvfKNMLERFM......AFLQIPKQSILAN
  595-  646 (76.93/31.08)	QIVNVINSNRRKPGAPQQ.QGQALPPQHM......QSQ............Q..PHSQS....hdNQMSSQMQTGNMQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.88|      14|     407|     718|     731|       6
---------------------------------------------------------------------------
  718-  731 (28.92/17.21)	VNI.....NP.MASHSGMGT
 1126- 1145 (16.96/ 6.95)	VNIseedaDPaAASEGGDGT
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP20422 with Med15 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) KQIVNVINSNRRKPGAPQQQGQALPPQHMQSQQPHSQSHDNQMSSQMQTGNMQGSMGGMQQNNMGSMQQNSVSSLQGSANPQQNMMNSMQPSSNLDQVQNSSMNSLQQVSGGSLQQNAVSGGQQVNINPMASHSGMGTLQPNSNMLQHQHIKQQEQLLQSQQLK
2) QYVHKQQLLQQQQQQQQQQFHQQAKQQQGGQLQGNQLGQLHQINDGGDVKLRQQMNMKSGAFQQQQATAAQRSAYHQQLKSGAPFSPQLLSAASPQMSQHASPQIDQQGMFNSHTKSGTPLQSANSPFAVPSPSTSSASPLPGPGEFERI
3) RKISLKMLTMETRSQNPMPDPMQANSGLNPADPGSQVMPQVNMQGQQLPIPVPSQSGQQQMMPQNMQNNIGSTGMQGSSSLSAALPTGSGLSQSTMSNVAGQNSNLQNMQNMSTMQQGSVGNTMGANSFTNQRQIPGRQQLVPQQQQQQQQQPQQQNPNSHYLYQQQLHQMAKQKLQQNNINPAMQSQMQQQQQQQQQQQQQQQNLLQSGMQPTMMQTPSLSGVVQNQQAAVPQSSQPLLNHPQSVLRQQQRQQQVQPTQQQVQPTQSNPMGQQANATSMQQNPLIGQQSNYSDMQQQRLLGQQNKLSSVQQPQQHLIGQHNNLSGMQQQHLGSQNNASGQQQLLGSQSGNTGMQTNQHSVQQMLQSKMPIQQQNQQSSATMLPTQVQQSQPQLQQQVMPQMQSQSGQLQQQMGMQQQPNLLQRDMQQRLPTAGGF
594
767
42
757
916
477










Molecular Recognition Features






MoRF SequenceStartStop




NANANA