<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP20410

Description Mediator subunit 8
SequenceMDGPVGVGQPQSQQQLPQQQQDQQQAKVVERLNPAVQQQLNLESVKTRAISLFKAITRILEDFDIIARTNSNPKWQDVLGQFSMVNLELYNIVEDIKKVSKAFVVHPKNVNGENAAILPVMISSKLLPEIEADDASKRDQLLYAMQNLSVPSQIEKLKARIDMIGAACESAEKVIADTRKTYFGTRQGPTNIMTLDKAQAAKIQEQENLLRHAVNHGQGLRLPPDQRQITSALPAHLVDVLPVGDNAQTVNESSGMYMKNTPPMVTNAVNNQGALMQGSGSQLMGRAAASPGGTGTPSFDNTTASPLPYANSPRSAANMMNTPSPQQQQTQQQQQQQQFQQQQRQRLMQLPQHQQQQLLAQQLRQNPMAGLAQNQLSQLHDLQGQGQQKYQLHGQNQMQFSQSLGAQQFQGRQLPSGGMQHGIAQSQLNQGSQLNRHINQMSSAANSALFNAAQGTPNNQMMSNMSAMMPSQPLVPRMQFGLSGGNRTLGSQNMNDQVFNMGAANPNTMMPMQQQQQQQQQQQHGSQGAFGNMQQNSQNLQANMMQNQQQNFQQHRQNNQQ
Length561
PositionHead
OrganismArtemisia annua (Sweet wormwood)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> campanulids> Asterales> Asteraceae> Asteroideae> Anthemideae> Artemisiinae> Artemisia.
Aromaticity0.04
Grand average of hydropathy-0.773
Instability index55.11
Isoelectric point9.44
Molecular weight62059.96
Publications
PubMed=29703587

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP20410
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     102.31|      18|      18|     328|     345|       1
---------------------------------------------------------------------------
  328-  345 (39.95/11.34)	QQTQQQQQQQQFQQQQRQ
  348-  365 (30.98/ 6.98)	MQLPQHQQQQLLAQQLRQ
  541-  557 (31.38/ 7.18)	QANMMQNQQQNFQQH.RQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     102.18|      35|      38|     455|     490|       4
---------------------------------------------------------------------------
  269-  310 (40.77/12.00)	VNNQGALMqgSGSQLMGRAAASPGGtGtpsfDNTTASPL.PYA
  462-  497 (61.41/21.78)	MSNMSAMM..PSQPLVPRMQFGLSG.G....NRTLGSQNmNDQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      77.03|      19|      38|     214|     232|       6
---------------------------------------------------------------------------
  196-  213 (17.18/ 6.21)	.DKAQAAKIQEQENLLRHA
  214-  232 (31.32/18.04)	VNHGQGLRLPPDQRQITSA
  250-  268 (28.52/15.70)	VNESSGMYMKNTPPMVTNA
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP20410 with Med8 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) QEQENLLRHAVNHGQGLRLPPDQRQITSALPAHLV
2) VLPVGDNAQTVNESSGMYMKNTPPMVTNAVNNQGALMQGSGSQLMGRAAASPGGTGTPSFDNTTASPLPYANSPRSAANMMNTPSPQQQQTQQQQQQQQFQQQQRQRLMQLPQHQQQQLLAQQLRQNPMAGLAQNQLSQLHDLQGQGQQKYQLHGQNQMQFSQSLGAQQFQGRQLPSGGMQHGIAQSQLNQGSQLNRHINQMSSAANSALFNAAQGTPNNQMMSNMSAMMPSQPLVPRMQFGLSGGNRTLGSQNMNDQVFNMGAANPNTMMPMQQQQQQQQQQQHGSQGAFGNMQQNSQNLQANMMQNQQQNFQQHRQNNQQ
204
240
238
561










Molecular Recognition Features






MoRF SequenceStartStop




NANANA