<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP20408

Description Mediator subunit 8
SequenceMDGPVGVGQPQSQQQLPQQQQDQQQAKVVERLNPAVQQQLNLESVKTRAISLFKAITRILEDFDIIARTNSNPKWQDVLGQFSMVNLELYNIVEDIKKVSKAFVVHPKNVNGENAAILPVMISSKLLPEIEADDASKRDQLLYAMQNLSVPSQIEKLKARIDMIGAACESAEKVIADTRKTYFGTRQGPTNIMTLDKAQAAKIQEQENLLRHAVNHGQGLRLPPDQRQITSALPAHLVDVLPVGDNAQTVNESSGMYMKNTPPMVTNAVNNQGALMQGSGSQLMGRAAASPGGTGTPSFDNTTASPLPYANSPRSAANMMNTPSPQQQQTQQQQQQQQFQQQQRQRLMQLPQHQQQQLLAQQLRQNPMAGLAQNQLSQLHDLQGQGQQKYQSLGAQQFQGRQLPSGGMQHGIAQSQLNQGSQLNRHINQMSSAANSALFNAAQGTPNNQMMSNMSAMMPSQPLVPRMQFGLSGGNRTLGSQNMNDQVFNMGAANPNTMMPMQQQQQQQQQQQHGSQGAFGNMQQNSQNLQANMMQNQQQNFQQHRQNNQQ
Length550
PositionHead
OrganismArtemisia annua (Sweet wormwood)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> campanulids> Asterales> Asteraceae> Asteroideae> Anthemideae> Artemisiinae> Artemisia.
Aromaticity0.04
Grand average of hydropathy-0.764
Instability index56.26
Isoelectric point9.44
Molecular weight60760.55
Publications
PubMed=29703587

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP20408
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.13|      14|      18|     328|     345|       1
---------------------------------------------------------------------------
   10-   23 (25.55/ 7.21)	PQSQQQLPQQ..QQDQ
  328-  343 (24.58/ 6.67)	QQTQQQQQQQqfQQQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     124.37|      32|      38|     356|     388|       2
---------------------------------------------------------------------------
  367-  403 (45.18/14.80)	PMAGLAQNQlSQLHDLQGQGQQkyQSLGA.QQFqgRQL
  500-  528 (48.09/13.41)	PMQ...QQQ..QQQQQQQHGSQ..GAFGNmQQN..SQN
  529-  550 (31.11/ 6.04)	LQANMMQNQ.QQNFQQHRQNNQ..Q.............
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      77.10|      27|     114|     292|     318|       4
---------------------------------------------------------------------------
  243-  297 (31.77/13.99)	VGDNAQtvneSSGMYMKNTPPMVTNavnnqgalmqgsgsqlmgraaaspGGTGTP
  298-  325 (45.33/22.74)	SFDNTT....ASPLPYANSPRSAAN.......................mMNTPSP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     142.49|      35|      37|      63|      98|       7
---------------------------------------------------------------------------
   33-   58 (27.76/13.24)	.........NPAVQQQLNLES.VKTRAISLFKAITR
   63-   98 (52.40/37.14)	FdIIARTNSNPKWQDVLGQFSMVNLELYNIVEDIKK
  103-  131 (36.55/20.22)	F.VVHPKNVNGENAAILP..VMISSKLLPEIE....
  133-  158 (25.77/11.73)	.......DDASKRDQLL..YAMQNLSVPSQIEKLK.
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP20408 with Med8 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) QEQENLLRHAVNHGQGLRLPPDQRQITSALPAHLV
2) VLPVGDNAQTVNESSGMYMKNTPPMVTNAVNNQGALMQGSGSQLMGRAAASPGGTGTPSFDNTTASPLPYANSPRSAANMMNTPSPQQQQTQQQQQQQQFQQQQRQRLMQLPQHQQQQLLAQQLRQNPMAGLAQNQLSQLHDLQGQGQQKYQSLGAQQFQGRQLPSGGMQHGIAQSQLNQGSQLNRHINQMSSAANSALFNAAQGTPNNQMMSNMSAMMPSQPLVPRMQFGLSGGNRTLGSQNMNDQVFNMGAANPNTMMPMQQQQQQQQQQQHGSQGAFGNMQQNSQNLQANMMQNQQQNFQQHRQNNQQ
204
240
238
550










Molecular Recognition Features






MoRF SequenceStartStop




NANANA