<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP20406

Description Surfeit locus protein 5 subunit 22 of Mediator complex
SequenceMNKAGAGGGTSGASGPTAAAAATAAQKQKSLQQRVDNDIGSIIDNFSSVVNVARVNDPPVRNSQEAFMMEVRAARMVQAADSLLKLVSELKQTAIFSGFASLNDHVDKRTTELNQQAEKTDRVLARIGEEAAASLKEMESHYYSSVLRSNQHLQQ
Length155
PositionHead
OrganismArtemisia annua (Sweet wormwood)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> campanulids> Asterales> Asteraceae> Asteroideae> Anthemideae> Artemisiinae> Artemisia.
Aromaticity0.04
Grand average of hydropathy-0.427
Instability index39.21
Isoelectric point6.84
Molecular weight16619.36
Publications
PubMed=29703587

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP20406
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     130.91|      42|      50|      42|      85|       1
---------------------------------------------------------------------------
   42-   85 (64.27/49.96)	IIDNFSSVVNvaRVNDPPVRNSQEAFMMEVRAARMVQAADSLLK
   95-  136 (66.64/45.70)	IFSGFASLND..HVDKRTTELNQQAEKTDRVLARIGEEAAASLK
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP20406 with Med22 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MNKAGAGGGTSGASGPTAAAAATAAQKQKSL
1
31










Molecular Recognition Features






MoRF SequenceStartStop




1) ASGPTAAAAATAAQ
2) HYYSSVLR
3) MNKAGAG
13
141
1
26
148
7