<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP20404

Description "WW domain, FF domain protein"
SequenceMANNSQYPGIQQPRHPFDPMGPPPNAYPSVPMQFHPAGPPRPGPPYMVSQQFLPVGRPNMVSQSMQHLPPRPGPPPPPMAHGLVTPPPPPPPAQAFSVPDGQSSRLLLSISPQAQQAVPINNNYMPGQNGPVALPINYNLPTSATTQVPPLPPAEQTSVAPSITVTTDPPKALEMAPSDWIEHTSHKGKSWEKPLDLMSPIERADATTNWKEYKAPDGRKYYYNKVTEQSKWRIPDELKFAREQVKTTCTTEPTKDPVNEPLVPTVIDSPSSQPQLVSSPVPVAPSIAAVQSGSLLNSEMSAGATESPKVTTNAAEQTAVPATPALSNTEDILVKEAVVAENGTPADNIEESSANIAALEENAVELEPLVYENKQEAKNAFKNLLETANIASDWIWDQAMRVIIKDRRYTALRTLAERKQAFSEFIAQKKKQEAEERRHKQKKAREDFKKMLEDSKDLTSSTKWREAILILEDDDRFKAVERPKEREDLFDDHITELEKKERSKALEEHKKYRKEYIEFLKSCDFITASSQWRRVQDRLETNESCSRLEKLDRLEIFQFMS
Length561
PositionUnknown
OrganismArtemisia annua (Sweet wormwood)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> campanulids> Asterales> Asteraceae> Asteroideae> Anthemideae> Artemisiinae> Artemisia.
Aromaticity0.06
Grand average of hydropathy-0.746
Instability index69.48
Isoelectric point5.70
Molecular weight62824.21
Publications
PubMed=29703587

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
GO - Biological Process
mRNA cis splicing, via spliceosome	GO:0045292	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP20404
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     136.89|      27|      29|      28|      54|       1
---------------------------------------------------------------------------
   24-   52 (48.27/20.14)	.P.....nayPSVPMQFH.PAGPPRPGPPYMVSQQF
   77-   96 (34.18/11.97)	..........P..PMAHG.LVTPPPPPPP...AQAF
   98-  129 (25.20/ 6.77)	VPdgqssrllLSISPQAQ.QAVPINN..NYMPGQN.
  130-  156 (29.25/ 9.11)	GP........VALPINYNlPTSATTQVPPLPPAEQ.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      74.06|      17|      18|     248|     264|       2
---------------------------------------------------------------------------
  248-  264 (30.59/14.74)	TCTTEPTKDP..VNEPLVP
  265-  282 (20.63/ 7.65)	TVIDSPSSQPqlVSSP.VP
  295-  311 (22.84/ 9.23)	LLNSEMSAGA..TESPKVT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|      56.96|      10|      40|     376|     385|       3
---------------------------------------------------------------------------
  376-  385 (15.58/10.34)	EAKNAFKNLL
  407-  416 (12.57/ 6.91)	RRYTALRTLA
  417-  426 (14.90/ 9.57)	ERKQAFSEFI
  443-  452 (13.92/ 8.45)	KAREDFKKML
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.61|      17|      17|     161|     177|       4
---------------------------------------------------------------------------
  161-  177 (30.84/18.88)	PSITVTTDPPKALE.....MAP
  179-  200 (28.77/17.08)	DWIEHTSHKGKSWEkpldlMSP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.37|      11|      14|     474|     485|       5
---------------------------------------------------------------------------
  475-  485 (18.75/14.16)	DRFKAVERPKE
  501-  511 (17.62/ 6.14)	ERSKALEEHKK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.94|      12|      50|      11|      23|       7
---------------------------------------------------------------------------
   11-   23 (24.08/13.37)	QQPRH.PFDPmGPP
   63-   75 (23.86/ 8.80)	QSMQHlPPRP.GPP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.67|      14|      17|     208|     224|       9
---------------------------------------------------------------------------
  208-  221 (27.03/18.90)	TNWKEYKAPDGRKY
  227-  240 (25.64/ 8.86)	TEQSKWRIPDELKF
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP20404 with Med35 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AREQVKTTCTTEPTKDPVNEPLVPTVIDSPSSQPQLVSSPVPVA
2) MANNSQYPGIQQPRHPFDPMGPPPNAYPSVPMQFHPAGPPRPGPPYMVSQQFLPVGRPNMVSQSMQHLPPRPGPPPPPMAHGLVTPPPPPPPAQAFSVPDGQSSRLLLSISPQAQQAVPINNNYMPGQNGPVALPINYNLPTSATTQVPPLPPAEQTSVAPSITVTTDPPKALEMAPSDWIEHTSHKGK
3) SLLNSEMSAGATESPKVTTNAAEQTAVPATPAL
241
1
294
284
189
326










Molecular Recognition Features






MoRF SequenceStartStop




1) GRKYYYNK
218
225