<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP20386

Description Pre-mRNA-processing protein 40A
SequenceMDNNNPQNQSLRPPAIGSQGFGTNYSMQFRPGVPAQPGHPYMQPASGTQQYRPMGQPGQFSQPMQQMPARPGQPAPSSQPMPMSYMQQPPQYQNPAAGPGGVPHSSYAFTAPPFGQPTNVSSQFHAVSQMHTPVAPTGGQPWMPSGNQGPGNVTPVSQPGQQPSTTAPTNQASSAGQEASAADWQEFTAADGRRYYYNKRTKQSSWEKPMELMTPLERADASTVWKEFTTAEGKKYYYNKDTKQSKWTIPEELKLAREQAEKEASRGTQSPAILTPSAIDQPSASASSANGVSSSPVAVMPVIPVGSAPSVASESSSLASPLIPAVGGSSMVSANVHSSPLGKTEKSSSHGAPEAVDGVSVQDTEEAKKGMAAAGKVNTTPSEEKVVDGETFIYATKQEAKAAFKSLLEDSNVRADWNWEQAMRVIINDKRYGALKALGERKQAFNEYLMQRKKLEAEERRLKQRKAKEEFTKMLEESKELTSSMRWSKAIALFEDDERYKAVDRSSDREDLFQSYLVDLQKKERAKAQEEQRQYRLEYRQFLETCGLIKVDTQWRKVQDRLEDDERCSRLEKFDRLEIFQEYIRDLEKEEDEQRKIKKERIKRVERKNRDEFRKMLDEHVVSGTLNAKTQWRDYCPKVKESVAYQAVATNTSGSTPKDLFEDVVEELERKYHEDKSRVKDALKLKKVAVLPTWTFEDFKAASDEDIISSLSDINLQLVFEDLIERAKEKEEKELKKRQRLVKDFTDLLYDMKEITASSTWEECHQLFEESSEYRAISDESIAREAFEEYVARLVEKAKEKERKREEEKARKEEKEKRKEKERKEREKEKEKEKEKERSKKDDSDSENIDTVSEHKEDKKREKDKDRKHRKRHQDDLSSDKDERDDSKKSRRHGSDRKKSRKHTYSPESDSESKHKKHKKDSRSKNGDGDVDGQEELEDGELGEDGEIQ
Length949
PositionUnknown
OrganismArtemisia annua (Sweet wormwood)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> campanulids> Asterales> Asteraceae> Asteroideae> Anthemideae> Artemisiinae> Artemisia.
Aromaticity0.07
Grand average of hydropathy-1.191
Instability index56.23
Isoelectric point6.29
Molecular weight108229.92
Publications
PubMed=29703587

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
GO - Biological Process
mRNA cis splicing, via spliceosome	GO:0045292	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP20386
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     147.27|      37|      38|     184|     220|       1
---------------------------------------------------------------------------
  184-  220 (75.12/44.72)	WQEFTAADGRRYYYNKRTKQSSWEKPMELMTPLERAD
  225-  261 (72.15/42.67)	WKEFTTAEGKKYYYNKDTKQSKWTIPEELKLAREQAE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      77.91|      16|      17|      49|      64|       3
---------------------------------------------------------------------------
   42-   60 (28.34/12.36)	MQPasgT.QQY..RPMGQPGQF
   61-   77 (26.18/10.91)	SQP...M.QQMpaRP.GQPAPS
   78-   92 (23.39/ 9.04)	SQP...MpMSY....MQQPPQY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     482.43|      65|      65|     397|     461|       4
---------------------------------------------------------------------------
  397-  461 (94.66/58.55)	KQ.EAKAAFKSLLED.S.N.VRADWN....WEQAMRVIINDKRYGAL...KALGERKQAFNEYLMQ.........RKKLEAEERR
  463-  529 (83.86/50.99)	KQrKAKEEFTKMLEE.SkE.LTSSMR....WSKAIALFEDDERYKAV...DRSSDREDLFQSYLVD.........LQKKERAKAQ
  532-  596 (85.71/52.29)	QR.QYRLEYRQFLET.C.GlIKVDTQ....WRKVQDRLEDDERCSRL...EKF.DRLEIFQEYIRD.........LEKEEDEQRK
  606-  671 (71.00/41.99)	ER.KNRDEFRKMLDE.H.V.VSGTLNaktqWRDYCPKVKESVAYQAVatnTSGSTPKDLFEDV...............VEELERK
  676-  734 (69.41/40.88)	KS.RVKDALK..LKK.V.A.VLPTWT....FED.FKAASDEDIISSL...SDI.NLQLVF.EDLIE.........RAK.EKEEKE
  738-  812 (77.80/46.75)	RQ.RLVKDFTDLLYDmK.E.ITASST....WEECHQLFEESSEYRAI...SDESIAREAFEEYVARlvekakekeRKREEEKARK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      73.96|      19|      19|     293|     311|       5
---------------------------------------------------------------------------
  133-  154 (27.50/13.47)	PVAPTGGQpwmPSG...NQGPGNVT
  282-  300 (27.24/13.27)	PSASASSA...NGV...SSSPVAVM
  301-  320 (19.22/ 7.24)	PVIPVGSA...PSVaseSSSLAS..
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      68.39|      15|      15|     898|     912|       6
---------------------------------------------------------------------------
  833-  847 (19.76/ 6.72)	EKEKERSKKDDSDSE
  898-  912 (24.66/10.19)	KKSRKHTYSPESDSE
  916-  930 (23.98/ 9.71)	KKHKKDSRSKNGDGD
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      89.23|      29|      29|     330|     358|      10
---------------------------------------------------------------------------
  330-  358 (47.66/31.36)	SMVSANVHSSPLGKTEKSSSHGAPEAV.DG
  360-  389 (41.57/26.29)	SVQDTEEAKKGMAAAGKVNTTPSEEKVvDG
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP20386 with Med35 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) KERKREEEKARKEEKEKRKEKERKEREKEKEKEKEKERSKKDDSDSENIDTVSEHKEDKKREKDKDRKHRKRHQDDLSSDKDERDDSKKSRRHGSDRKKSRKHTYSPESDSESKHKKHKKDSRSKNGDGDVDGQEELEDGELGEDGEIQ
2) MDNNNPQNQSLRPPAIGSQGFGTNYSMQFRPGVPAQPGHPYMQPASGTQQYRPMGQPGQFSQPMQQMPARPGQPAPSSQPMPMSYMQQPPQYQNPAAGPGGVPHSSYAFTAPPFGQPTNVSSQFHAVSQMHTPVAPTGGQPWMPSGNQGPGNVTPVSQPGQQPSTTAPTNQASSAGQEASAADWQ
3) SANVHSSPLGKTEKSSSHGAPEAVDGVSVQDTEEAKKGMAAAGKVNTTPS
4) WTIPEELKLAREQAEKEASRGTQSPAILTPSAIDQPSASASSANGVSSSPVAVM
801
1
333
247
949
185
382
300










Molecular Recognition Features






MoRF SequenceStartStop




1) ADGRRYYYNKR
2) KHKKHKKD
3) LRPPAI
4) QEELEDGELGE
5) TVWKEFTTAEGKKYYYNK
6) YSMQFR
190
914
11
934
223
25
200
921
16
944
240
30