<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP20385

Description Pre-mRNA-processing protein 40A
SequenceMDNNNPQNQSLRPPAIGSQGFGTNYSMQFRPGVPAQPGHPYMQPASGTQQYRPMGQPGQFSQPMQQMPARPGQPAPSSQPMPMSYMQQPPQYQNPAAGPGGVPHSSYAFTAPPFGQPTNVSSQFHAVSQMHTPVAPTGGQPWMPSGNQGPGNVTPVSQPGQQPSTTAPTNQASSAGQEASAADWQEFTAADGRRYYYNKRTKQSSWEKPMELMTPLERADASTVWKEFTTAEGKKYYYNKDTKQSKWTIPEELKLAREQAEKEASRGTQSPAILTPSAIDQPSASASSANGVSSSPVAVMPVIPVGSAPSVASESSSLASPLIPAVGGSSMVSANVHSSPLGKTEKSSSHGAPEAVDGVSVQDTEEAKKGMAAAGKVNTTPSEEKVVDGETFIYATKQEAKAAFKSLLEDSNVRADWNWEQAMRVIINDKRYGALKALGERKQAFNEYLMQRKKLEAEERRLKQRKAKEEFTKMLEESKELTSSMRWSKAIALFEDDERYKAVDRSSDREDLFQSYLVDLQKKERAKAQEEQRQYRLEYRQFLETCGLIKVDTQWRKVQDRLEDDERCSRLEKFDRLEIFQEYIRDLEKEEDEQRKIKKERIKRVERKNRDEFRKMLDEHVVSGTLNAKTQWRDYCPKVKESVAYQAVATNTSGSTPKDLFEDVVEELERKYHEDKSRVKDALKLKKVAVLPTWTFEDFKAASDEDIISSLSDINLQLVFEDLIERAKEKEEKELKKRQRLVKDFTDLLYDMKEITASSTWEECHQLFEESSEYRYIR
Length778
PositionUnknown
OrganismArtemisia annua (Sweet wormwood)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> campanulids> Asterales> Asteraceae> Asteroideae> Anthemideae> Artemisiinae> Artemisia.
Aromaticity0.08
Grand average of hydropathy-0.904
Instability index54.42
Isoelectric point6.18
Molecular weight87861.21
Publications
PubMed=29703587

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
GO - Biological Process
mRNA cis splicing, via spliceosome	GO:0045292	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP20385
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     147.27|      37|      38|     184|     220|       1
---------------------------------------------------------------------------
  184-  220 (75.12/43.93)	WQEFTAADGRRYYYNKRTKQSSWEKPMELMTPLERAD
  225-  261 (72.15/41.93)	WKEFTTAEGKKYYYNKDTKQSKWTIPEELKLAREQAE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      75.57|      16|      17|      49|      64|       2
---------------------------------------------------------------------------
   36-   55 (25.42/10.18)	QPGHpYMQPasgT.QQY..RPMG
   56-   72 (28.86/12.49)	QPGQ.FSQP...M.QQMpaRP.G
   73-   87 (21.29/ 7.41)	QPAP.SSQP...MpMSY....MQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.32|      17|      19|     293|     311|       3
---------------------------------------------------------------------------
  133-  152 (27.45/ 8.27)	PVAPTGGQPwmpSG...NQGPGN
  301-  320 (23.88/11.27)	PVIPVGSAP...SVaseSSSLAS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     419.34|      66|      66|     400|     465|       4
---------------------------------------------------------------------------
  400-  463 (91.49/55.61)	.....AKAAFKSLLEDS.N.VRADWN....WEQAMRVIINDKRYGALKALGERKQAFNEYLM.....QRKKLEAEER..RLK
  464-  538 (78.14/46.47)	QR..kAKEEFTKMLEESkE.LTSSMR....WSKAIALFEDDERYKAVDRSSDREDLFQSYLVdlqkkERAKAQEEQRqyRLE
  539-  598 (79.98/47.73)	YR...Q......FLETC.GlIKVDTQ....WRKVQDRLEDDERCSRLEKF.DRLEIFQEYIR.....DLEKEEDEQR..KIK
  606-  673 (73.19/43.08)	ER..kNRDEFRKMLDEH.V.VSGTLNaktqWRDYCPKV...KESVAYQAVATNTSGSTPKDL.....FEDVVEELER..KYH
  674-  736 (70.16/41.00)	EDksrVKDALK..LKKV.A.VLPTWT....FED.FKAASDEDIISSLSDI.NLQLVF.EDLI.....ERAK.EKEEK..ELK
  737-  774 (26.38/11.01)	KRqrlVKD.FTDLLYDMkE.ITASST....WEECHQLFEESSEY......................................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.86|      14|      16|      95|     108|       6
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   95-  108 (27.35/14.66)	PAAG.PGGVPHSSYA
  112-  126 (23.51/11.65)	PPFGqPTNVSSQFHA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.21|      11|      42|     285|     296|       7
---------------------------------------------------------------------------
  285-  296 (15.93/15.20)	SASSANgVSSSP
  330-  340 (20.28/12.44)	SMVSAN.VHSSP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP20385 with Med35 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MDNNNPQNQSLRPPAIGSQGFGTNYSMQFRPGVPAQPGHPYMQPASGTQQYRPMGQPGQFSQPMQQMPARPGQPAPSSQPMPMSYMQQPPQYQNPAAGPGGVPHSSYAFTAPPFGQPTNVSSQFHAVSQMHTPVAPTGGQPWMPSGNQGPGNVTPVSQPGQQPSTTAPTNQASSAGQEASAADWQ
2) SANVHSSPLGKTEKSSSHGAPEAVDGVSVQDTEEAKKGMAAAGKVNTTPS
3) WTIPEELKLAREQAEKEASRGTQSPAILTPSAIDQPSASASSANGVSSSPVAVM
1
333
247
185
382
300










Molecular Recognition Features






MoRF SequenceStartStop




1) AADWQEFTAADGRRYYYNKR
2) LRPPAIG
3) TVWKEFTTAEGKKYYYNK
4) YSMQFR
181
11
223
25
200
17
240
30