<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP20378

Description Pre-mRNA-processing protein 40A
SequenceMDNNNPQNQSLRPPAIGSQGFGTNYSMQFRPGVPAQPGHPYMQPASGTQQYRPMGQPGQFSQPMQQMPARPGQPAPSSQPMPMSYMQQPPQYQNPAAGPGVPHSSYAFTAPPFGQPTNVSSQFHAVSQMHTPVAPTGGQPWMPSGNQGPGNVTPVSQPGQQPSTTAPTNQQASSTGQEPSAADWQEFTAADGRRYYYNKRTKQSSWEKPMELMTPLERADASTVWKEFTTAEGKKYYYNKDTKQSKWTIPEELKLAREQAEKEASRGTQSPAILTPSVIDQPSASASSANGVSSSPVAVMPVIPVGSAPPSVASESSSLASPLIPAVGGSSMVSASMHSSPLGKTEKSSSHGAPEAVDGVSVQDTEEAKKGMAAAGKVNTTPSEEKVVDGETFIYATKQEAKAAFKSLLEDSNVRADWNWEQAMRVIINDKRYGALKALGERKQAFNEYLMQRKKLEAEERRLKQRKAKEEFTKMLEESKELTSSMRWSKAIALFEDDERYKAVDRSSDREDLFQSYLVDLQKKERAKAQEEQRQYRLEYRQFLETCGLIKVDTQWRKVQDRLEDDERCSRLEKFDRLEIFQEYIRDLEKEEDEQRKIKKERIKRVERKNRDEFRKMLDEHVVSGTLNAKTQWRDYCPKVKESVAYQAVATNTSGSTPKDLFEDVVEELERKYHEDKSRVKDALKLKKVAVLPTWTFEDFKAASDEDIISSLSDINLQLVFEDLIERAKEKEEKELKKRQRLVKDFTDLLYDMKEITASSTWEECHQLFEESSEYRAISDESIARESFEEYVARLVEKAKEKERKREEEKARKEEKEKRKEKERKEREKEKEKEKEKERSKKDDSDSENIDTVSEHKEDKKREKDKDRKHRKRHQDDLSSDKDERDDSKKSRRHGSDRKKSRKHTYSPESDSESKHKKHKKDSRSKNGDGDVDGQEELEDGELGEDGEIQ
Length950
PositionUnknown
OrganismArtemisia annua (Sweet wormwood)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> campanulids> Asterales> Asteraceae> Asteroideae> Anthemideae> Artemisiinae> Artemisia.
Aromaticity0.07
Grand average of hydropathy-1.201
Instability index57.58
Isoelectric point6.29
Molecular weight108503.27
Publications
PubMed=29703587

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
GO - Biological Process
mRNA cis splicing, via spliceosome	GO:0045292	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP20378
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     100.58|      16|      17|      49|      64|       1
---------------------------------------------------------------------------
   25-   44 (18.33/ 6.13)	YsMQF..RP.GvpaQPGHpYMQP
   48-   63 (35.66/18.66)	T.QQY..RPMG...QPGQ.FSQP
   64-   80 (25.73/11.48)	M.QQMpaRP.G...QPAP.SSQP
   81-   95 (20.86/ 7.96)	MpMSY....MQ...QPPQ.YQNP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      76.17|      19|      19|     800|     818|       2
---------------------------------------------------------------------------
  800-  818 (30.93/13.57)	KEKE.....RK.REEEKARKEEKEK
  820-  839 (24.81/ 9.35)	KEKE.....RKeREKEKEKEKEKER
  862-  885 (20.43/ 6.32)	REKDkdrkhRK.RHQDDLSSDKDER
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     431.55|      65|      65|     398|     462|       3
---------------------------------------------------------------------------
  398-  449 (65.51/38.11)	......................KQ.EAKAAFKSLLED.S.N.VRADWN....WEQAMRVIINDKRYGAL...KALGERKQAFNEY
  450-  517 (84.21/51.30)	LMQRKKLEAEERR........lKQrKAKEEFTKMLEE.SkE.LTSSMR....WSKAIALFEDDERYKAV...DRSSDREDLFQSY
  518-  584 (78.64/47.37)	LVDLQKKERAKAQ.......eeQR.QYRLEYRQFLET.C.GlIKVDTQ....WRKVQDRLEDDERCSRL...EKF.DRLEIFQEY
  585-  665 (72.42/42.99)	IRDLEKEEDEQRKikkerikrvER.KNRDEFRKMLDE.H.V.VSGTLNaktqWRDYCPKVKESVAYQAVatnTSGSTPKDLFEDV
  666-  723 (51.17/27.99)	......VEELERK.....yhedKS.RVKDALK..LKK.V.A.VLPTWT....FED.FKAASDEDIISSL...SDI.NLQLVF.ED
  724-  791 (79.60/48.05)	LIERAK.EKEEKE......lkkRQ.RLVKDFTDLLYDmK.E.ITASST....WEECHQLFEESSEYRAI...SDESIARESFEEY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     149.91|      39|      40|     184|     222|       4
---------------------------------------------------------------------------
  184-  222 (78.84/52.98)	WQEFTAADGRRYYYNKRTKQSSWEKPMELMTPLERA..DAS
  225-  265 (71.07/46.96)	WKEFTTAEGKKYYYNKDTKQSKWTIPEELKLAREQAekEAS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     107.02|      21|      21|     294|     314|       5
---------------------------------------------------------------------------
  146-  170 (30.17/18.15)	N.QGPGNVTPVSQP..GQQPsttaPTNQ
  293-  313 (36.98/24.18)	S.SSPVAVMPVIPV..GSAP....PSVA
  314-  336 (19.49/ 8.68)	SeSSSLA.SPLIPAvgGSSM....VSAS
  337-  357 (20.37/ 9.46)	MhSSPLGKTEKSSS..HGAP....EAV.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.25|      16|      17|     896|     911|       6
---------------------------------------------------------------------------
  896-  911 (27.42/12.88)	SDRKKSRKHTYSPESD
  914-  929 (29.82/14.67)	SKHKKHKKDSRSKNGD
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP20378 with Med35 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) KERKREEEKARKEEKEKRKEKERKEREKEKEKEKEKERSKKDDSDSENIDTVSEHKEDKKREKDKDRKHRKRHQDDLSSDKDERDDSKKSRRHGSDRKKSRKHTYSPESDSESKHKKHKKDSRSKNGDGDVDGQEELEDGELGEDGEIQ
2) MDNNNPQNQSLRPPAIGSQGFGTNYSMQFRPGVPAQPGHPYMQPASGTQQYRPMGQPGQFSQPMQQMPARPGQPAPSSQPMPMSYMQQPPQYQNPAAGPGVPHSSYAFTAPPFGQPTNVSSQFHAVSQMHTPVAPTGGQPWMPSGNQGPGNVTPVSQPGQQPSTTAPTNQQASSTGQEPSAADWQEFTA
3) SSMVSASMHSSPLGKTEKSSSHGAPEAVDGVSVQDTEEAKKGMAAAGKVNTTPS
4) WTIPEELKLAREQAEKEASRGTQSPAILTPSVIDQPSASASSANGVSSSPVAVMPVIPVGSAPPSVASESSSLAS
802
1
330
247
950
189
383
321










Molecular Recognition Features






MoRF SequenceStartStop




1) DGRRYYYNKR
2) EELEDGELGE
3) EGKKYYYNK
4) HRKRH
5) KHKKHKKD
6) LRPPAIG
7) TVWKEFTT
8) YSMQFR
191
936
232
870
915
11
223
25
200
945
240
874
922
17
230
30