<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP20358

Description U-box domain-containing protein kinase family protein
SequenceMEGAQRMNQIRYPVIDTSEIMEIRTDIVETIPPNPRAEENNIYVAVGKEVKESQLALRWALDNLGGWGILYTHQIVAHRAAEMQEMNQILDKYKQICQKAGVFAEVHYIEMNSIEKGIVDFILKHNVRKLAMGAAADKQFSKRMVDVRSKKAVYVKLKAAAFCQIQFICKGNVIFTRQGTLDGVGFSTASPSASPNTTSGTDNRRVMSNNRGTELPAFSSPSFNTDSTSTSRLTSGRAFDEWSGISRSTNSRFSSCSSELADDLGQTPYSISEVNEVQSDYGAVTVFIEEIPNHPPSSVMERGMNDELYDQLEQAMAEVDTSKREAFEESIRRRKAEKDAMDARRKVKALENMYGEELRRRQEIDETLTKTNQITDLNHTVQEVEQKMFSAIELLKHYKGERDEMQVECDHALQLVEELSSKQTGEASSSGVSQFYNEFSLTEIQDATRNFDQSLKIGEGGYGSIFRGFLRHTEVAIKMLHSHSLQGPSEFQQEVNVLSKLRHPNLVTLIGVCPDAWTIVYEYLPGGSLEDRLGCKDNTPPLSWQNRIRIAAELCSVIIFLHSCGIIHGDLKPDNLLLDKNLVTKVSDFGICRVLSGQEFSDNNTSICRTGPKGTFLYMDPEFLSTGELTSKSDTYSFGVILLRLLTGKPALGLTKEVKCALNEKKLKNILDPAAGDWPFVQAQQLAVLAMNCCDMIRQNRPDLVSEVWRVLEPMAVSCGLSSFRVGSEGQSEIPHYFVCPIFQETMQDPVVAADGFTYEAEAIKGWLDSGHNTSPMTNLELANSNLVPNHALRSAIQEWLQ
Length802
PositionTail
OrganismArtemisia annua (Sweet wormwood)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> campanulids> Asterales> Asteraceae> Asteroideae> Anthemideae> Artemisiinae> Artemisia.
Aromaticity0.07
Grand average of hydropathy-0.363
Instability index44.64
Isoelectric point5.35
Molecular weight89681.49
Publications
PubMed=29703587

Function

Annotated function Functions as an E3 ubiquitin ligase. 
ECO:0000256	ARBA:ARBA00003861
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP20358
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.31|      18|      25|     191|     214|       1
---------------------------------------------------------------------------
  191-  208 (32.88/39.06)	PS.ASPN.TTSGTDNRRVMS
  216-  235 (22.43/ 8.18)	PAfSSPSfNTDSTSTSRLTS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.69|      17|      25|     116|     140|       2
---------------------------------------------------------------------------
  129-  153 (18.53/27.23)	KLAMGAAAdkqfskrmVDVRSKKAV
  156-  173 (26.16/12.99)	KLKAAAFC.......qIQFICKGNV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      78.02|      17|      45|     259|     275|       4
---------------------------------------------------------------------------
  259-  275 (29.17/18.36)	ELADDLGQTPYSISEVN
  276-  292 (26.30/15.90)	EVQSDYGAVTVFIEEIP
  307-  320 (22.55/12.68)	ELYDQLEQ...AMAEVD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     120.28|      39|      50|     488|     532|       6
---------------------------------------------------------------------------
  488-  532 (55.86/57.43)	PSEFQQEVNVLSKLrhPNLVTLIGVCpdawTIVYEYL.PGGSLEDR
  541-  580 (64.42/44.42)	PLSWQNRIRIAAEL..CSVIIFLHSC....GIIHGDLkPDNLLLDK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.40|      15|      43|     350|     368|       7
---------------------------------------------------------------------------
  327-  341 (24.53/15.66)	FEESIRRRKAEKDAM
  354-  368 (24.88/10.66)	YGEELRRRQEIDETL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP20358 with Med32 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) FSTASPSASPNTTSGTDNRRVMSNNRGTELPAFSSPSFNTDS
2) GAVTVFIEEIPNHPPSSVMERGMNDELYDQLEQAMAEVDTSKREAFEESIRRRKAEKDAMDARRKV
186
282
227
347










Molecular Recognition Features






MoRF SequenceStartStop




NANANA