<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP20214

Description Kinase-like domain-containing protein
SequenceMQRAEDREVDDKDDRGGGRPSLLTSTSASTSFNTITPTQRPPSKRKREGTHHEGDEGEDGQEEDQEEKGLDEEIMPPYKSKVRVLEEYHIIGFISSGTYGRVYKARSKLPGNTKEYAIKKFKPDKEGEVIQYTGISQSACREMALCSELSHENVIHLHEIILEDKCIYMVFEYAEHDLLQIVHYHSHPERRPIPEATIKSVLWQLLNGVSYLHQNWVLHRDLKPANIMVTAAGEVKIGDLGLARLFWKPLQSLYTGDKVVVTIWYRAPELLLGSKHYTAAIDLWAVGCIFAELLALRPIFKGEEAKMEKKSTVPFQRNQMQKIIEILGTPTKERWPAVTQQPEYNQLQTFKQYTNNLEAWYHQIGATNALGFQLLSGLLNYDPTQRLTAQAALEHQYFSDGAKLTLNAFEGQSFDYPHRRVSQDDNDISLPGTKRSGLPDDSLGGSRAKRLKEG
Length454
PositionKinase
OrganismTuber borchii (White truffle)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Pezizomycetes> Pezizales> Tuberaceae> Tuber.
Aromaticity0.09
Grand average of hydropathy-0.615
Instability index44.39
Isoelectric point6.17
Molecular weight51597.68
Publications

Function

Annotated function
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein kinase activity	GO:0004672	IEA:InterPro
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP20214
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     126.14|      39|     343|      37|      77|       1
---------------------------------------------------------------------------
   37-   77 (67.49/40.48)	PTQRPPSKRKREgtHHEGDEGE.......DGQEEDQEEKGL...DEEIMPP
  383-  431 (58.65/29.73)	PTQRLTAQAALE..HQYFSDGAkltlnafEGQSFDYPHRRVsqdDNDISLP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.10|      17|      73|     268|     284|       2
---------------------------------------------------------------------------
  268-  284 (31.62/24.02)	PEL..LLGSKHYTAAIDLW
  342-  360 (28.48/20.88)	PEYnqLQTFKQYTNNLEAW
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP20214 with CDK8 domain of Kingdom Fungi

Intrinsically Disordered Regions

IDR SequenceStartStop
1) MQRAEDREVDDKDDRGGGRPSLLTSTSASTSFNTITPTQRPPSKRKREGTHHEGDEGEDGQEEDQEEKGLDEEIMP
2) RVSQDDNDISLPGTKRSGLPDDSLGGSRAKRLKEG
1
420
76
454

Molecular Recognition Features

MoRF SequenceStartStop
1) GGGRPSLLTS
2) LGGSRAKRLKEG
3) MQRAEDREVDDKD
16
443
1
25
454
13