<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP20191

Description Vacuolar calcium ion transporter
SequenceMKEASSEPPNIDGSRSGAQPTAPTAQGLSEQPRLQEFDEKNTRLDNQNGRKTKSLHKIPSAGDVSSPAAGSGSVLEAPSKAEEPAQGETPSTTSKNAGFFAELKRSVRIVITYSWLNVFMVFVPVGIAVSQVPGVPAGLIFGMNAIAIIPLAGLLAFATESVALKMGDALGALLNVTFGNAVELIIFILALVKNEIRVVQSALLGSILANLLLILGMSMLLGGLRFREQVYNSTVTQMSACLLSLSVISLVLPTAFHASFKDNDKADRESLKISRATSVVLLIVYVIYLTFQLKSHAYMYESTPQHIIDAELAPGPAAGFLDSSSSDDSSSSSSDSSDSDSSHGTMRKRMKKVLRNRRHRRSSAASVDTADTKGTRSASFATNNTTTPQEEVSEAKASRQGVPRTASYEGSEHAVDDDDEEEAERSHRRRRYRRHRHRRSKKEARKAKKEAKNAQSQNNLPESIPENKGEGEPRRVDFAVQDDLEAGPSTNGVKRPFPLRGISVKALAPVFTEKPPTASGPAPHVRYGIRRTNSLPDRLQFRAPGAMLPAQIPPILNATGVKSTDSDEEDEEEHLSQFSAVILLLVSTALVAVCAEFLVDSIQEVVKTSHINQVGIGLIILPIVGNAAEHVTAIKVAYKNNMDLAIGVAVGSSIQIALLLTPFMVILGWIMNKEMTLYFTLFETVCLFVSAFIVNFLVLDGRSNYLEGALLCAVYIIIAVVAFFYPDSEDASVWGGGT
Length738
PositionKinase
OrganismFusarium culmorum
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes> Hypocreomycetidae> Hypocreales> Nectriaceae> Fusarium.
Aromaticity0.06
Grand average of hydropathy-0.073
Instability index52.44
Isoelectric point6.57
Molecular weight79679.85
Publications

Function

Annotated function
GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
GO - Biological Function
GO - Biological Process
transmembrane transport	GO:0055085	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP20191
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     107.40|      27|      27|     373|     399|       2
---------------------------------------------------------------------------
  370-  396 (41.75/26.47)	ADT..................KG.TRSASFATNNTTTPQEEVSEAK
  397-  424 (37.23/22.82)	ASR..................QGvPRTASYEGSEHAVDDDDEEEAE
  425-  468 (28.42/15.71)	RSHrrrryrrhrhrrskkearKA.KKEAKNAQSQNNLP.ESIPENK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.34|      12|      28|     514|     525|       3
---------------------------------------------------------------------------
  514-  525 (24.23/15.19)	KPPTASGPA..PHV
  542-  555 (19.10/10.27)	RAPGAMLPAqiPPI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      84.41|      26|      28|     681|     708|       4
---------------------------------------------------------------------------
  681-  708 (38.99/34.04)	LFETVCLFVSafIVNFLVLDGRSNYLEG
  710-  735 (45.41/32.10)	LLCAVYIIIA..VVAFFYPDSEDASVWG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      88.33|      31|      34|     141|     174|       6
---------------------------------------------------------------------------
  141-  174 (40.70/39.23)	FGmNAIAIIPLagLLAFATESVALKMGDALGALL
  178-  208 (47.63/32.13)	FG.NAVELIIF..ILALVKNEIRVVQSALLGSIL
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP20191 with Med13 domain of Kingdom Fungi

Intrinsically Disordered Regions

IDR SequenceStartStop
1) GFLDSSSSDDSSSSSSDSSDSDSSHGTMRKRMKKVLRNRRHRRSSAASVDTADTKGTRSASFATNNTTTPQEEVSEAKASRQGVPRTASYEGSEHAVDDDDEEEAERSHRRRRYRRHRHRRSKKEARKAKKEAKNAQSQNNLPESIPENKGEGEPRRVDFAVQDDLEAGPSTNGVKRPFP
2) MKEASSEPPNIDGSRSGAQPTAPTAQGLSEQPRLQEFDEKNTRLDNQNGRKTKSLHKIPSAGD
3) SPAAGSGSVLEAPSKAEEPAQGETPSTTSK
319
1
66
498
63
95

Molecular Recognition Features

MoRF SequenceStartStop
1) RGISVKALAPVFT
2) RRSKKEARKAKKEAKN
3) RYGIR
4) TAPTAQGLSEQPRLQEFDEKN
500
438
526
21
512
453
530
41