Description | Mediator of RNA polymerase II transcription subunit 7 |
Sequence | MDDQPEPHSLASTFPNPPEFWREFTPDRIAELNELRLSRASPDQDDGNIGRIPDLPEHLRHLQPPPEPADGRWRVFGDQYMLDDKLPTLEEQGIQNLPATASSSAKDAKHYDRAFELKRLVKSLLLNFLELNGVLARNPADAEAKILDIRTIFINIHHILNEYRPHQARESAIEMMQDHLDRTRTETAAIRTQVDKARKVLEGLGSLDLSLFQEQQLDGADRILDASPLTDMTAADMHRGERRERAAAAWCMADALLN |
Length | 258 |
Position | Middle |
Organism | Trichoderma citrinoviride |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes> Hypocreomycetidae> Hypocreales> Hypocreaceae> Trichoderma. |
Aromaticity | 0.05 |
Grand average of hydropathy | -0.640 |
Instability index | 52.91 |
Isoelectric point | 5.08 |
Molecular weight | 29308.60 |
Publications |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery.
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364060 ECO:0000256 ARBA:ARBA00003669 |
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro |
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro |
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro |
Binary Interactions |
Repeats | >MDP20144 --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 58.71| 19| 49| 3| 24| 1 --------------------------------------------------------------------------- 11- 47 (25.94/15.56) ASTFPNPPEFWREFtpdriaelnelrlsraspDQDDG 49- 68 (32.77/10.28) IGRIPDLPEHLRHL.................qPPPEP --------------------------------------------------------------------------- --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 63.20| 21| 39| 86| 107| 2 --------------------------------------------------------------------------- 86- 107 (31.97/24.66) LPTLEEQGI..QNlPATASSSAKD 126- 148 (31.22/19.19) LNFLELNGVlaRN.PADAEAKILD --------------------------------------------------------------------------- |
MoRF Sequence | Start | Stop |
1) PPEFWREFTPDRIAELNELRLS 2) WRVFG | 17 73 | 38 77 |
© 2021 Shailesh Lab
Designed by Dr. Shailesh Lab & Dr. Jitendra K. Thakur Lab