<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP20069
Description |
Mediator of RNA polymerase II transcription subunit 17 |
Sequence | MSSSSFALGPLALGDRRPQNLSDFIQRVNAERGGFRNITEESLREEAEADANGVLDSKEVDMLDDKAQDIGSGHQPSPEEFQTAISKVYQQAEVAHQNAMLALDFLSLLLTKEDSPQAGASLSPALRELVGTGVLGVDKLAKSNMTEARLQDHKAIATGWKLANIDKTVDSLLSSASRLQKEMTVEAKYWEEVLAVSDKGWAITHVSNELQDLGVRYGFSEAAPTFRKTSLAPMRRSDDGSVDLDCGALLGESKRLRVTLEERGKIVGRSALPEPLPQDAPLEDRVLEARNTIFAQELWHELDREGRLFPAYGISIEEGVLSYTYAEQSKVVIQLEPLTRSPDQEPVRPLPGDHHAEALSAILHQMLTYAHRVNNSKRSRSNPRNRKAATRSQPYQLVRPLLAYTKHGILVNEATNFISGLVTILQSAGFSTAMFKLTESPIAPDFATANHSIPEALITYLLRPLECQFEVNITPDVRILIHCRTAMRSAILPTFHIYPLPIAPGTPSPLHRLYPPSEFSNHEGYGLADLKYYLQEAVTRVLVDRAAAFIPPVVPSTSQTSGELEANWIRQSTGKALKNVNDEREEVSIEVVNSGTATGGQQLELRVAGSWNAGQAVPGRRVWIWTVQEAVEGLKHEGFEGVVKSILSREAPSQLD |
Length | 656 |
Position | Head |
Organism | Coniella lustricola |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes>
Sordariomycetidae> Diaporthales> Schizoparmaceae> Coniella.
|
Aromaticity | 0.06 |
Grand average of hydropathy | -0.323 |
Instability index | 53.73 |
Isoelectric point | 5.53 |
Molecular weight | 72237.70 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364140
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GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
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GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
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Interaction
Repeat regions
Repeats |
>MDP20069
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 123.04| 41| 106| 179| 239| 1
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110- 153 (62.65/48.66) LTKEDSPQAGASLSPALRELvgtGV.LGVDKLA....KSNMTEARLQDH
194- 239 (60.40/44.55) LAVSDKGWAITHVSNELQDL...GVrYGFSEAAptfrKTSLAPMRRSDD
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
3| 195.88| 56| 59| 397| 454| 2
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389- 432 (54.47/37.06) ..............ATRSQ.P.........yqLVRPLLAYTKHG...ILVNEATNFISGLV...TILQSAGFST
435- 494 (81.58/64.10) FKLTESPIAPDFATANHSI.P.........eaLITYLLRPLECQ...FEVN.ITPDVRILIhcrTAMRSAILPT
495- 562 (59.83/38.23) FHIYPLPIAPGTPSPLHRLyPpsefsnhegygLA.DLKYYLQEAvtrVLVDRAAAFIPPVV..pSTSQTSG...
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