<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP20066

Description Kinase-like domain-containing protein
SequenceMTTDPSSAASQGSNRVLAHQHAAKRNVQAAFEDPTDRGAFGHVGYQSKVRVIDRYKVIGFISSGTYGRVYKAVGRQGQVGEFAIKKFKPDKEGEVITYTGISQSAVREMALCSELSHISVIKLHEIILEDKCIFMVFEYAEHDLLQIIHHHTQQPRHPIPPATIKSIMFQLFNGCQYLHANWVLHRDLKPANIMVTSAGEVKIGDLGLARMFQKPLHNLYSGDKVVVTIWYRAPELLLGSRHYTPAIDMWALGCIFAELLSLRPIFKGEEAKMDSKKTVPFQRNQMQKIVDIMGLPTKERWPLLVHMPEYQALQQLTPPMAHASGHHGRGHHHHHSQQQPPGSQLEKWYFATINTSTGTSTPAANGGPSSLASLGQEGYKLLAGLLEYDPEKRLTAAQALQHPFFTTGPDRPSANCFEGLKMEYPHRRVSQDDNDIRTSSLPGTKRSGLPDDSLRPGKRLKEG
Length463
PositionKinase
OrganismConiella lustricola
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes> Sordariomycetidae> Diaporthales> Schizoparmaceae> Coniella.
Aromaticity0.08
Grand average of hydropathy-0.433
Instability index36.37
Isoelectric point9.13
Molecular weight51743.55
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein kinase activity	GO:0004672	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP20066
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      79.96|      22|     181|     149|     173|       1
---------------------------------------------------------------------------
  149-  173 (35.18/27.63)	HHHTQQprHPiPPATIKSIMFQLFN
  333-  354 (44.78/23.76)	HHHSQQ..QP.PGSQLEKWYFATIN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      72.95|      25|      45|     196|     224|       3
---------------------------------------------------------------------------
  196-  224 (33.34/33.99)	TSAgeVKIGDLG..LARMFQkpLHNLYSGDK
  244-  270 (39.61/24.83)	TPA..IDMWALGciFAELLS..LRPIFKGEE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      70.87|      19|      40|     362|     380|       4
---------------------------------------------------------------------------
  362-  380 (33.76/17.80)	PAANGGPSSLASLGQEGYK
  403-  421 (37.11/20.19)	PFFTTGPDRPSANCFEGLK
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP20066 with CDK8 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AAQALQHPFFTTGPDRPSANCFEGLKMEYPHRRVSQDDNDIRTSSLPGTKRSGLPDDSLRPGKRLKEG
2) QLTPPMAHASGHHGRGHHHHHSQQQPPGSQLEKWYFA
396
315
463
351










Molecular Recognition Features






MoRF SequenceStartStop




1) LEKWYFAT
2) SLRPGKRLKE
345
453
352
462