Description | Mediator of RNA polymerase II transcription subunit 11 (Fragment) |
Sequence | ESQEGHQSQSQPYRELAATHIRELSDIKERIPTIVQQAAFAVSQLTNKPLDIPAKNPPGHVSDSVPSRIEIIKRANDDLLAVVQQLRTDLHAQVDALANEGVIPTQQTIKHAPVLQGQNQAAQDRQHDPEATVTNEGLGNLDVGNLNARAGVREVKGEEALTRVKEVLEELAKSTQGGDEMAVE |
Length | 184 |
Position | Head |
Organism | Corynespora cassiicola Philippines |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Dothideomycetes> Pleosporomycetidae> Pleosporales> Corynesporascaceae> Corynespora. |
Aromaticity | 0.01 |
Grand average of hydropathy | -0.598 |
Instability index | 41.86 |
Isoelectric point | 5.06 |
Molecular weight | 20006.98 |
Publications | PubMed=29551995 |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364147 |
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro |
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro |
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro |
Binary Interactions |
Repeats | >MDP20042 --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 46.09| 15| 18| 75| 92| 1 --------------------------------------------------------------------------- 78- 92 (25.21/20.49) DLLA...VVQQLRTDLHA 95- 112 (20.88/ 7.55) DALAnegVIPTQQTIKHA --------------------------------------------------------------------------- --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 53.31| 16| 18| 17| 32| 2 --------------------------------------------------------------------------- 17- 32 (26.59/17.13) AATHIRELSDIKERIP 38- 53 (26.73/17.25) AAFAVSQLTNKPLDIP --------------------------------------------------------------------------- |
MoRF Sequence | Start | Stop |
1) QSQPYRELAATHIRELSDIKERIPTIVQ 2) RIEIIK | 9 68 | 36 73 |
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