Description | Mediator of RNA polymerase II transcription subunit 7 |
Sequence | MAEEQEQQQSNQAAAAFPAPPFFWQHFTPENVERIEKLRAAQSAKQDVTTETSSKLPPRILDLPKELRFLQPPDPPASGRYRSFGSAYTIQDELPSLETQGYDQLYTPPDTPTGTGKHADRALVLKRLAKSLLLNFLELLGIMSLNPEHAEEKIIDLRTLFINFHHLLNEYRPHQARESLILMMQDQLEKSRAETEGIMKMKEKVEGILEGLSEVKLEDKSAIEGQLHDEEPEDDGRDIWNQLEKEFG |
Length | 248 |
Position | Middle |
Organism | Rutstroemia sp. NJR-2017a WRK4 |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Leotiomycetes> Helotiales> Rutstroemiaceae> Rutstroemia> unclassified Rutstroemia. |
Aromaticity | 0.07 |
Grand average of hydropathy | -0.703 |
Instability index | 50.28 |
Isoelectric point | 4.90 |
Molecular weight | 28345.60 |
Publications |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery.
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364060 ECO:0000256 ARBA:ARBA00003669 |
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro |
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro |
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro |
Binary Interactions |
Repeats | >MDP20033 --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 71.80| 20| 35| 55| 76| 2 --------------------------------------------------------------------------- 55- 76 (33.87/26.79) KLPPriLDLPKELRFLQPPDPP 93- 112 (37.93/23.37) ELPS..LETQGYDQLYTPPDTP --------------------------------------------------------------------------- --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 72.06| 22| 25| 132| 155| 3 --------------------------------------------------------------------------- 132- 155 (31.80/27.92) LLLNFLELLGimSLNPEHAEEKII 160- 181 (40.26/27.72) LFINFHHLLN..EYRPHQARESLI --------------------------------------------------------------------------- --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 46.49| 13| 14| 218| 230| 4 --------------------------------------------------------------------------- 218- 230 (22.22/13.09) EDKSAIEGQLHDE 234- 246 (24.27/14.83) DDGRDIWNQLEKE --------------------------------------------------------------------------- |
MoRF Sequence | Start | Stop |
1) RDIWNQLEKEFG 2) RIEKLR | 237 34 | 248 39 |
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