<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP20030

Description CMGC CDK CDK8 kinase protein
SequenceMSLTSNPLSSGGPSSVSTSRTQNLKRSVQAAFEEPTDRGTNQNVGYQSKVRIIDRYSIIGFISSGTYGRVYKARSREDAPGLFAIKKFKPDKEGEQIQYTGISQSAVREMALCSELNHMNIIRLVETILEDKCIFMVFEYAEHDLLQIIHHHTQPTRHPIPAPTVKSIMFQLLNGCQYLHANWVLHRDLKPANIMVTSSGEVKIGDLGLARLFNKPLHSLFSGDKVVVTIWYRAPELLLGSRHYTPAIDMWAIGCIFAELLSLRPIFKGEEAKMDSKKTVPFQRNQMQKIVDIMGLPTKEKWSHLVSMPEYSQLSTLSASAHAKAGGSSLEKWYFQTINAHSQTSVPSSNSSLGVEGYKLLSALLEYDPEKRLTAQAALTHPFFSTGDKVSANVFEGAKVEYPHRRVSQDDNDIRTGSLPGTKRSGLPDDSRPTKRMKE
Length439
PositionKinase
OrganismRutstroemia sp. NJR-2017a WRK4
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Leotiomycetes> Helotiales> Rutstroemiaceae> Rutstroemia> unclassified Rutstroemia.
Aromaticity0.08
Grand average of hydropathy-0.379
Instability index37.66
Isoelectric point9.17
Molecular weight49070.48
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein kinase activity	GO:0004672	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP20030
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      90.93|      27|      29|     300|     327|       2
---------------------------------------------------------------------------
  300-  327 (42.95/29.28)	EKWsHLVSMPEYSQLSTLSASAHAKAGG
  331-  357 (47.98/28.55)	EKW.YFQTINAHSQTSVPSSNSSLGVEG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      30.20|       9|      33|     363|     372|       4
---------------------------------------------------------------------------
  363-  372 (12.28/11.39)	ALLEYdPEKR
  398-  406 (17.92/10.66)	AKVEY.PHRR
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP20030 with CDK8 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MSLTSNPLSSGGPSSVSTSRTQNLKRSVQAAFEEPTDRGT
2) VEYPHRRVSQDDNDIRTGSLPGTKRSGLPDDSRPTKRMKE
1
400
40
439










Molecular Recognition Features






MoRF SequenceStartStop




NANANA