<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP19999
Description |
Mediator of RNA polymerase II transcription subunit 5 |
Sequence | MPRYLDMEPPKSVAAQTWQTLFKKAILKRYRPEELAKAFRELQMRYRTRPGDIATTLLGLRAANGNPDDVLVFKYAEFLLKNDYFTASDLLSALLKSSNYVRSKTSPNTRFSMPTCEERIFMIVTQFHIISDLPSSAVALQDLVFVIYRWLKVVGEDVVGKQLSGLQTMDAQLNGIYEALAQLTLATLGNKGMRKVTQYRWWKERRATVVNEMQNYDVNVLRWMNSQLAGRLRALLNVPPYLEMDADGKYKFSDEQILAQVEELPVVRSRAGIFVWLNAALAARPLTDDMTILTYIQGRSSDNPQSIVVDLLVAAFDVLTNFMLTKEPRQNAKVVRSFICNKLPVLIAILANNMQPAISADACIQMALMPGGMISMDPLPPISAGATDVRDSLKTTRLEFLQACVLHGLVNEQTVALILQESVALPRVIKLNKDSLVAQCANNVSKLAEHIEELAGMQGNVGAIAGCVVETVNNMCMSKDTMSLKSVCDKLIRRIPYMDFVMQYTQPGMLLLPLCNLLNDWTHDQDQSEFTPAYEEFASILLFTLAVIYRYDLAFADIGILGDSFVARLLEDMTVSKPPGELQSEQASQLTQWIEGLFAVDEHGDTSGIGDEVMRQCSPQSFYTLVPTLFEQSILACRSQVLSMNTFKSGLELLLEPFLLPSLVMGLGWLAKHSWEDHNDADVLIQVLEKLLKPSSSAPETQAMHRAILAMVATPLYCSLEEYCRKQPNKKANELLELLKPHLNQQRSLHSRQSELDQWQQDGTGLQGRVQQAIRELITWSSTSTSPPNPPPHYTHRTFAIACQLLDSQTLLDAIIAEVSKTEYNNVPIALDVCTSLICAPAPVPMGAQQATHWTSPTGQLRSRVRIASADAQAILDLAKSHAETLVRLGRRVQAQMSFAAQMPAIAMPMPMQDQSTDQMMQDLGLALDSNASASNVDATMATNASAIASNAEMSGMDQPIDLTNLNNASADELAKLTVDSDAMNLDQNNQFLADFGMGVGDAQSNAQNNAMTNQDDDIFAGLNMDMGELDDFTFD |
Length | 1036 |
Position | Tail |
Organism | Cercospora berteroae |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Dothideomycetes>
Dothideomycetidae> Mycosphaerellales> Mycosphaerellaceae> Cercospora.
|
Aromaticity | 0.07 |
Grand average of hydropathy | -0.084 |
Instability index | 46.83 |
Isoelectric point | 4.96 |
Molecular weight | 114856.56 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364142
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP19999
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 60.75| 18| 18| 918| 935| 4
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918- 935 (30.92/19.01) DQMMQDLGLALDSNASAS
938- 955 (29.82/18.07) DATMATNASAIASNAEMS
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 115.04| 36| 140| 91| 130| 5
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91- 130 (54.60/37.51) LSALLKSSNYVRSKTSPNTRFSmptcEERIFMIVTQFHII
232- 267 (60.44/31.60) LRALLNVPPYLEMDADGKYKFS....DEQILAQVEELPVV
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 39.62| 11| 14| 318| 328| 6
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318- 328 (19.43/11.54) VLTNFMLTKEP
334- 344 (20.19/12.26) VVRSFICNKLP
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