Description | Mediator of RNA polymerase II transcription subunit 31 |
Sequence | MSAPDRSSGEAAVPEYRIHHGGHDRFTLELEFVQMLANPQYMSYLADKKLLENEEFVAYLDYLQYFRDPTYLRYLQYPGPTLRALELLQEERFRKDILSPEVAGRLFHEGMEASTST |
Length | 117 |
Position | Middle |
Organism | Cercospora berteroae |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Dothideomycetes> Dothideomycetidae> Mycosphaerellales> Mycosphaerellaceae> Cercospora. |
Aromaticity | 0.13 |
Grand average of hydropathy | -0.540 |
Instability index | 52.02 |
Isoelectric point | 5.02 |
Molecular weight | 13681.24 |
Publications |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364129 |
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro |
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro |
GO - Biological Process | regulation of transcription, DNA-templated GO:0006355 IEA:InterPro |
Binary Interactions |
Repeats | >MDP19995 --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 69.10| 19| 28| 14| 41| 1 --------------------------------------------------------------------------- 23- 41 (34.12/33.05) HDRFTLELEFVQMLANPQY 53- 71 (34.97/13.98) NEEFVAYLDYLQYFRDPTY --------------------------------------------------------------------------- |
MoRF Sequence | Start | Stop |
1) AAVPEYRIHHG 2) DYLQYFRDPTYLRYLQYP | 11 61 | 21 78 |
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