<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP19983
Description |
Mediator of RNA polymerase II transcription subunit 6 |
Sequence | MATASATQLDEQVYTFPPLIEWWVNTMGGKAMDENMIHRYMSESPFFEWSSKNGLLFEQGKFHNPTHEMCNNRKALEENLRGRVGLEYMIVQDPQPVADKELAAQGVTTGIYVIRKQDRQRAPSGARVRPPGVILEGNWELTVLGTYYTMGQNVYQAPNMFDVVENRLLAAASSLNKFIDTTSMLPRYAPASGYTYLPPSQPSKRPGTGSIAGSPAGSREGSVVPGLDSQSFRSGSLLPDSNVSTSKTTSDHDQTRLLASSLAMSIKYAHDYTDENPLVGEPGNFKFAMTEAAVKKRRAEEEAAAAEARAKKELALNSRGVSPKQDIASPKADKAAAPAAFTTETKLKAEEKRKNSAFGGKRKKDRKKGMSSAGPSPTTPGPSTAPTPKAS |
Length | 391 |
Position | Head |
Organism | Cercospora berteroae |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Dothideomycetes>
Dothideomycetidae> Mycosphaerellales> Mycosphaerellaceae> Cercospora.
|
Aromaticity | 0.07 |
Grand average of hydropathy | -0.620 |
Instability index | 51.53 |
Isoelectric point | 9.27 |
Molecular weight | 42455.35 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364143
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP19983
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 103.29| 34| 39| 303| 338| 1
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305- 338 (51.24/32.68) AAEARAKKELALNSRGVSPKQDIASPKADKAAAP
342- 375 (52.05/27.21) TTETKLKAEEKRKNSAFGGKRKKDRKKGMSSAGP
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 54.83| 16| 39| 192| 208| 2
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192- 208 (27.18/20.55) SGyTYLPPSQPSKRPGT
234- 249 (27.65/15.30) SG.SLLPDSNVSTSKTT
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 96.50| 33| 39| 73| 110| 5
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73- 110 (46.01/41.12) RKalEENLRGRVGLEymiVQDPQPV..ADKELAAQGV..TTG
115- 151 (50.48/30.21) RK..QDRQRAPSGAR...VRPPGVIleGNWELTVLGTyyTMG
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