<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP19979

Description Uncharacterized protein
SequenceMSRAAPPPPPPSSSSHSRRSTAAKSAGLANQHQPAGITAQETSHAYRSSPIDHILAEQGLERYHLEPPTWRAPWIVKSSDGGIPTSSKANETVASVGLGPNKSLIRLAGAPAPVAGPGGAAPAYGTVPLHAAASADAATGNEATCSAWPVFYPPHDGMDEDRLTEQVVKQGFAAKSLVSAETFSAHQHIYDKLKTGDILGNLSRLVSAVREKAESQLPTYGPSTFRLPSRITLTDSKREAWFSDLASPSVPLSKLSRSVPHGYKGEKGLDMLAHRRVEIDRAVWFVRAFGGVEIQSLAKSRPLATAIYLYTTEFTGVVCEFLRKQLGEVVLPGAVSNNPTSTPTSTHASPLGPPVSTTMANASRARSGSLSMQAKAAAASAAAAAAAAQSDSSKLGTPGLLDETKRKAWEEKYHYTIRLVSSLYRESLLDRLQFLHFIVSLLESRPALAPGDQLGQLSFAVSLIDGYLDDILESEPETARLVGGCMSRIQELEHTPTSSLRDVIRTNLASIVKTAFGKSPDAFASLLPSPVYSSLAFPLVDTEGLERVLTKPISGKHGEGAPDADTRLRSQFYAEIADLRARRQLLSATLQAQSDPSTAIEDLAADDRARLAAIEHLDAFEFPQRIQETHRNIFVTARPDLVLHWDIALPLLFTYATTTSRPCGPHRRYAAARLISLERERLQDGVKRVTRSSSQSRLTHVEDAFVRWVDGLDASIPRSSIRSLAEELFRIGVMNYGAYLQRMIARGETERDSNGEGGESIHLWILRTVPLESSLAGVKSRIAGGGKVVADRARRIEHALTCVKQAIDDLFSPEAPGKMASVQSSCAVLFEQLDEAIKDGAHWNITREMIPNALSSWLPSTEAALALPADLVAVAVAVFKKGEDWAALLQLLAALVQLQLSEDTVGLIVDVIESRLDIWAALDLLPDLSQALMARFVSIKKAEQPIPRRLLSLLVTFAGHDLLDAEAQMTLKQELQSMVVAASPTSARQSLPQLPIPLPEMQALLADSSPAATSQLASSLWHRYRGHPHWITALLDSSVLYIPQLGAAEPLIELITNLESRTPLGVFSAALAPWTSNMSVSQAETIFGGAYGEATAFLFAELGIAGVFDTPALLKDLVAPVRRTTLKSLLRATGTSCSTDTSLAILHNVQLVFAPVIAPASSPGDSVLPGAHRLPRRHRISARRAALTRCVNLPAIAEALAGLIVEQEVARRLGYDDVAEHTGAYFVRLASLPRLRALFARVPRALRDGMLDNEALNALPTVQQLRPNLLAGLLVVLKDGGAASPASLGSTEELDIFLSGLSIWRLNVSKVELVACLERLELDPTISAVERHAALHTLSGHFLERVCGGDGKSYLGEQVLVSVAFERLADAVSILTDDSAHDDSRERASTVVRTTSTLLDKFLQVGTAISRIASSVRFLESIRAALLASCRASASGARVPGANMHDPVQIARLAVLALRCLARSKEGEPTELLKDCLILLAFQAATLSKGSLQYSQQATLLLDACSAILYALPDIGPSVRAPTLSGLVNAAPPFAISLENLPDAVLDRLCRLFGPRHPTSSVRNPWELLDHADPAMTQAALARKAAISANSYYAPPSQLVNLGPIDLASFRARVSATIPAVTAADASSSVSTSSAHSGASTAGTQQHQQQQQRRFEKGRQTNFDFETPCTTLGVAARDHRRTLNVTRLVSSRLEAAAAASAQAALTAAAAAASKKSAAPSSAAKHASATPAVPVSATAPLAATSGRGAKRRNSQQQGSSGASEIVVIDSDEEATGAGNKAATSLAPPKAKKAKTASNGSSASGTSGKTASKTTAGKAPSKTTRKRK
Length1826
PositionKinase
OrganismRhodotorula taiwanensis
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Pucciniomycotina> Microbotryomycetes> Sporidiobolales> Sporidiobolaceae> Rhodotorula.
Aromaticity0.05
Grand average of hydropathy-0.065
Instability index49.62
Isoelectric point8.77
Molecular weight194427.83
Publications
PubMed=29375494

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP19979
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     145.08|      36|      37|    1553|    1588|       1
---------------------------------------------------------------------------
 1569- 1607 (46.41/19.03)	LDHADPAMTQAALARKAAISansyYAP......PSQLVNlGPIDL
 1693- 1733 (32.22/10.89)	LEAAAAASAQAALTAAAAAAskksAAPssaaKHASATPA.VP...
 1734- 1766 (41.77/16.37)	VSATAPL...AATSGRGAKR....RNS....QQQGSSGA.SEIVV
 1767- 1787 (24.67/ 6.56)	ID.SDEEATGA..GNKAATS....LAP......P...........
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     160.99|      44|      70|     891|     934|       2
---------------------------------------------------------------------------
  858-  888 (32.56/16.59)	................................LPSTEA......................ALALPADLVAVAVAV..FKKG..ED.WAAL........
  891-  929 (55.12/34.55)	................................LLAALV......................QLQLSEDTVGLIVDV..IESR..LDIWAALDL.LPDLS
  930- 1001 (34.25/17.93)	QALMArfvsikkaeqpiprrllsllvtfaghdLLDAEA......................QMTLKQELQSMVVAAspTSAR..QSL.PQLPIpLPEM.
 1002- 1076 (39.05/21.75)	QALLA..................dsspaatsqLASSLWhryrghphwitalldssvlyipQLGAAEPLIELITN...LESRtpLGVFSA.AL.APWTS
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     405.46|     132|     148|     289|     435|       3
---------------------------------------------------------------------------
  289-  426 (203.09/102.25)	FggveIQSLAKSRP.LATAIYLYTTEFT.....GVVCEFLRKQLGEVVLPGAVSNNpTSTPTSTHASPLGPPVSTTMANASRARSGSlSMQAKAAAASAAAAAAAAQSDSSKLGTPGLLDE.TKRKAWEEKYHYTIRLVSSLYRE
  437-  575 (202.36/98.15)	F....IVSLLESRPaLAPGDQLGQLSFAvslidGYLDDILESEPETARLVGGCMSR.IQELEHTPTSSLRDVIRTNLASIVKTAFGK.SPDAFASLLPSPVYSSLAFPLVDTEGLERVLTKpISGKHGEGAPDADTRLRSQFYAE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     361.98|     109|     125|    1099|    1223|       4
---------------------------------------------------------------------------
   80-  172 (116.01/53.07)	............................DGGIPTSS.KANETVASV..GLGPNKSLIrL..AGAPAPVAGPG....GAA.PAY................GTVPLHAAASA..DAATgnEATCSAWPVFYPPHDGMdedrLTEQVVKQ..GF
 1099- 1215 (163.64/111.87)	FAELGiagvfDTPAlLKDLVAPVRRTTLKSLLRATG.TSCSTDTSL..AILHNVQLV.F..APVIAPASSPG....DSVLPGA................HRLPRRHRISA..RRAA..LTRCVNLPAIAEALAGL....IVEQEVARrlGY
 1226- 1335 (82.33/36.82)	FVRLA.....SLPR.LRALFARVPRALRDGMLDNEAlNALPTVQQLrpNLLAGLLVV.LkdGGAASPASLGSteelDIFLSGLsiwrlnvskvelvaclERLELDPTISAveRHAA..L................................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.83|      19|      22|    1446|    1467|       5
---------------------------------------------------------------------------
 1446- 1464 (30.03/10.59)	DPVQIAR..LAVLALRCLARS
 1468- 1488 (20.80/11.23)	EPTELLKdcLILLAFQAATLS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.47|      16|      22|     767|     782|       6
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  767-  782 (25.93/16.01)	RTVPLESSLAGVKSRI
  792-  807 (27.53/17.48)	RARRIEHALTCVKQAI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     112.75|      35|     170|    1620|    1654|      11
---------------------------------------------------------------------------
 1620- 1654 (58.55/25.35)	AVTAADASSSVSTSSAHSGASTAGTQQHQQQQQRR
 1792- 1826 (54.19/22.98)	AKTASNGSSASGTSGKTASKTTAGKAPSKTTRKRK
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP19979 with Med12 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AAAAASKKSAAPSSAAKHASATPAVPVSATAPLAATSGRGAKRRNSQQQGSSGASEIVVIDSDEEATGAGNKAATSLAPPKAKKAKTASNGSSASGTSGKTASKTTAGKAPSKTTRKRK
2) DASSSVSTSSAHSGASTAGTQQHQQQQQRRFEKGRQTNF
3) MSRAAPPPPPPSSSSHSRRSTAAKSAGLANQHQPAGITAQETSHAYRSSPIDH
1708
1625
1
1826
1663
53










Molecular Recognition Features






MoRF SequenceStartStop




1) ATSLAPPKAKKAKTASNG
2) LTAAAAAA
3) SKTTRKRK
1781
1705
1819
1798
1712
1826