<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP19911

Description Mediator complex subunit 13 like
SequenceMDKNFVRIGKWFVRPYEKDEKPVNKSEHLSCAFTFFLHGESNVCTSVEIAQHQPIYLINEEHIHMAQSSPAPFQVLVSPYGLNGTLTGQAYKMSDPATRKLIEEWQYFYPMVLKKKEESKEEDELGYDDDFPVAVEVIVGGVRMVYPSAFVLISQNDIPVPQSVASAGGHIAVGQQGLGSVKDPSNCGMPLTPPTSPEQAILGESGGMQSAASHLVSQDGGMITMHSPKRSGKIPPKLHNHMVHRVWKECILNRTQSKRSQMSTPTLEEEPASNPATWDFVDPTQRVSCSCSRHKLLKRCAVGPNRPPTVSQPGFSAGPSSSSSLPPPASSKHKTTERQEKGDKLQKRPLIPFHHRPSVAEELCMEQDTPGQKLGLAGIDSSLEVSSSRKYDKQMAVPSRNTSKQMNLNPMDSPHSPISPLPPTLSPQPRGQETESLDPPSVPVNPALYGNGLELQQLSTLDDRTVLVGQRLPLMAEVSETALYCGIRPSNPESSEKWWHSYRLPPSDDAEFRPPELQGERCDAKMEVNSESTALQRLLAQPNKRFKIWQDKQPQMQPLHFLDPLPLSQQPGDSLGEPTTPMKMGLAPTMMICLLTFHSQMIWTMILAY
Length609
PositionMiddle
OrganismPan paniscus (Pygmy chimpanzee) (Bonobo)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Primates> Haplorrhini> Catarrhini> Hominidae> Pan.
Aromaticity0.06
Grand average of hydropathy-0.548
Instability index71.97
Isoelectric point6.36
Molecular weight67516.14
Publications
PubMed=22722832

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP19911
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     455.83|      93|      93|     294|     386|       1
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  187-  288 (99.69/37.39)	......CGM.PLTPPTspeqailgesggmqsaashlVSQ..DGgmiTMH..SPKRS.GKIPPKLHNHmvHRVWKE........................CILNRTQSKRSQ.....M...STPTL.EEE...PA.SNPAT...WDFVDPTQ..RVS
  294-  386 (161.49/64.63)	HKLLKRCAVGPNRPPT....................VSQ..PG...FSA..GPSSS.SSLPPPASSK..HKTTER........................QEKGDKLQKRPL.....IPFHHRPSV.AEELCMEQ.DTPGQKLGLAGIDSSL..EVS
  389-  479 (114.27/43.81)	RKYDKQMAV.PSR.NT....................SKQ..MN...LNPmdSPHSPiSPLPPTLSPQ..PRGQE.........................TESLDP....PS.....VPVN..PALyGNGLELQQlSTLDDRTVLVGQRLPLmaEVS
  485-  587 (80.39/28.88)	......CGIRPSNPES....................SEKwwHS...YRL..PPSDD.AEFRPPELQG..ERCDAKmevnsestalqrllaqpnkrfkiwQDKQPQMQ..PLhfldpLPLSQQP...GDSL.GEP.TTP.MKMGLA...........
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     243.77|      75|      93|       8|      84|       2
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    8-   84 (126.76/76.64)	IGKW.FVRPYEKDEKPVNKSE.HLSCAFTFFLHGESnVCTSVEIAQHQPIYLINEEHIHMAQS.SPAPFQVLVSPYGLnG
  102-  179 (117.01/63.27)	IEEWqYFYPMVLKKKEESKEEdELGYDDDFPVAVEV.IVGGVRMVYPSAFVLISQNDIPVPQSvASAGGHIAVGQQGL.G
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP19911 with Med13 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) CAVGPNRPPTVSQPGFSAGPSSSSSLPPPASSKHKTTERQEKGDKLQKRPLIPFHHRPSVAEELCMEQDTPGQKLGLAGIDSSLEVSSSRKYDKQMAVPSRNTSKQMNLNPMDSPHSPISPLPPTLSPQPRGQETESLDPPSVPVNPALYGNGLEL
2) ECILNRTQSKRSQMSTPTLEEEPASNPATWDFV
3) KDPSNCGMPLTPPTSPEQAILGESGGMQSAASHLVSQDGGMITMHSPKRSGKIPPKLH
300
249
182
455
281
239










Molecular Recognition Features






MoRF SequenceStartStop




NANANA