<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP19902

Description Uncharacterized protein
SequenceIRNMVAVLEVISSLEKYPITKEALEETRLGKLINDVRKKTKNEELAKRAKKLLRSWQKLIEPAHQHEAALRGLAGATGSANGGAHNCRPEVGAAGPPRSIHDLKSRNDLQRLPGQRLDRLGSRKRRGDQRDLGHPGPPPKVSKASHDPLVPNSSPLPTNGISGSPESFASSLDGSGHAGPEGSRLERDENDKHSGKIPVNAVRPHTSSPGLGKPPGPCLQPKASVLQQLDRVDETPGPPHPKGPPRCSFSPRNSRHEGSFARQQSLYAPKGSVPSPSPRPQALDATQVPSPLPLAQPSTPPVRRLELLPSAESPVRWLEQPESHQRLAGPGCKAGLSPAEPLLSRAGFSPDSSKADSDAASSGGSDSKKKKRYRPRDYTVNLDGQVAEAGVKPVRLKERKLTFDPMTRQIKPLTQKEPVRADSPVHMEQQSRTELDKQEAKASLQSPFEQTNWKELSRNEIIQSYLSRQSSLLSSSGAQTPGAHHFMSEYLKQEESTRQGARQLHVLVPQSPPTDLPGLTREVTQDDLDRIQASQWPGVNGCQDTQGNWYDWTQCISLDPHGDDGRLNILPYVCLD
Length576
PositionUnknown
OrganismPan paniscus (Pygmy chimpanzee) (Bonobo)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Primates> Haplorrhini> Catarrhini> Hominidae> Pan.
Aromaticity0.04
Grand average of hydropathy-0.874
Instability index62.34
Isoelectric point9.36
Molecular weight62894.79
Publications
PubMed=22722832

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP19902
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     431.13|      96|      98|      73|     170|       1
---------------------------------------------------------------------------
   73-  165 (153.50/59.67)	......L.....A...............GATGS....ANGGAHNCRPEVGAAG.PPRSiHdLKSRNDLQR...LPGQRLDRLGSRKRRGDQRD........LGHPGPP.P...KVSKASHDPLVPNSSPLPTNGISGSP
  166-  257 (124.38/43.06)	ESFASsLdgsghA...............GPEGSrlerDENDKHSGKIPVNAVR.P....H..TSSPGLGK...PPGPCLQPKASVLQQLDRVD.........ETPGPPhP...K......GP..PRCSFSPRN..SRHE
  258-  301 (68.38/20.67)	GSFAR.................................................................qqsLYAP..........KG...S........VPSPSPR.P...QALDATQ...VP..SPLPLAQPSTPP
  312-  413 (84.88/27.27)	ES...........pvrwleqpeshqrlaGPGCK....A..GLSPAEPLLSRAGfSPDS...SKADSDAAS...SGGS..D..SKKKKRYRPRDytvnldgqVAEAGVK.PvrlKERKLTFDPMTRQIKPL.........
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.80|      19|      19|     421|     439|       2
---------------------------------------------------------------------------
  421-  439 (32.59/21.06)	ADSPVHMEQQSRTELDKQE
  442-  460 (33.21/21.60)	ASLQSPFEQTNWKELSRNE
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      40.01|      13|      22|     465|     479|       4
---------------------------------------------------------------------------
  465-  479 (17.33/18.60)	YLSRQSSllSSSGAQ
  490-  502 (22.68/15.91)	YLKQEES..TRQGAR
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP19902 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) HQHEAALRGLAGATGSANGGAHNCRPEVGAAGPPRSIHDLKSRNDLQRLPGQRLDRLGSRKRRGDQRDLGHPGPPPKVSKASHDPLVPNSSPLPTNGISGSPESFASSLDGSGHAGPEGSRLERDENDKHSGKIPVNAVRPHTSSPGLGKPPGPCLQPKASVLQQLDRVDETPGPPHPKGPPRCSFSPRNSRHEGSFARQQSLYAPKGSVPSPSPRPQALDATQVPSPLPLAQPSTPPVRRLELLPSAESPVRWLEQPESHQRLAGPGCKAGLSPAEPLLSRAGFSPDSSKADSDAASSGGSDSKKKKRYRPRDYTVNLDGQVAEAGV
2) PVRLKERKLTFDPMTRQIKPLTQKEPVRADSPVHMEQQSRTELDKQEAKASLQSPFEQ
3) RQGARQLHVLVPQSPPTDLPGLTREVTQDDLDRIQASQWP
64
393
498
391
450
537










Molecular Recognition Features






MoRF SequenceStartStop




1) KKKKRYRPRDYTVNL
2) VRRLELLP
368
302
382
309