<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP19804

Description Mediator complex subunit 14
SequenceMLEVPNKPTQLSYKYYFMSVNASDREDSPAMALLLQQFKENIQDLVFRTKTGKQTRTNAKRKLSDDPCPVESKKMKRSGEMCAFNKVLAHFVAMCDTNMPFVGLRLELSNLEIPHQGVQVEGDGFSHAIRLLKIPPCKGISEETQKALDRCLLDCTFRLQGRNNRTWVAELVFANCPLNGTSTREQGPSRHVYLTYENLLSEPVGGRKVVEMFLNDWNSIARLYECVLEFARSLPDIPAHLNIFSEVRVYNYRKLILCYGTTKGSSISIQWNSIHQKFHISLGTVGPNSGCSNCHNTILHQLQEMFNKTPNVVQLLQVLFDTQAPLNAINKLPTVPMLGLTQRTNTAYQCFSILPQSSTHIRLAFRNMYCIDIYCRSRGVVAIRDGAYSLFDNSKLVEGFYPAPGLKTFLNMFVDSNQDARRRSVNEDDNPPSPIGGDMMDSLISQLQPPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGPSPATRMPGMSPANPSLHSPVPDASHSPRTAELFCCCSHDGQQHSEEVCRDESSTTRYMTSRQYFIAYML
Length634
PositionTail
OrganismCallithrix jacchus (White-tufted-ear marmoset)
KingdomMetazoa
Lineage
Aromaticity0.08
Grand average of hydropathy-0.391
Instability index62.75
Isoelectric point8.54
Molecular weight70099.94
Publications

Function

Annotated function
GO - Cellular Component
GO - Biological Function
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP19804
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     295.81|      62|      64|     449|     510|       1
---------------------------------------------------------------------------
  391-  444 (78.54/33.38)	.......FDNSKLVEGFYPA.PGLKTFLNMFVDSNQD.ARRRSVNEDDNPPSPIGGDMMD..SLI
  449-  510 (117.02/53.23)	PPPQQQPFPKQPGTSGAYPL.TSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAP..SPA
  516-  577 (100.25/44.58)	PPPSSHGISIGPGASFASPHgTLDPSSPYTMV..SPSGRAGNWPGS.PQVSGPSPATRMPgmSPA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     194.55|      60|      66|      67|     132|       3
---------------------------------------------------------------------------
   63-  131 (93.19/80.00)	LsddPCPVESKKMKRSGEMCAFNkvlAHFVAMCDTNMPFVGlrlELSNLEIPHQGVQVEGDGFSHAIRL
  132-  194 (101.35/70.83)	LkipPCKGISEETQKALDRCLLD...CTFRLQGRNNRTWVA...ELVFANCPLNGTSTREQGPSRHVYL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.24|      18|      53|     282|     301|       4
---------------------------------------------------------------------------
  260-  277 (31.94/15.08)	GTTKGSSISIQ.WNSIHQK
  283-  301 (29.30/18.75)	GTVGPNSGCSNcHNTILHQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      33.98|       9|      19|     348|     357|       5
---------------------------------------------------------------------------
  348-  357 (14.24/10.41)	YqCFSILPQS
  369-  377 (19.75/ 9.85)	Y.CIDIYCRS
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP19804 with Med14 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) NQDARRRSVNEDDNPPSPIGGDMMDSLISQLQPPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGPSPATRMPGMSPANPSLHSPVPDAS
417
589

Molecular Recognition Features

MoRF SequenceStartStop
1) LSYKYYFMSV
11
20