<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP19793

Description Mediator of RNA polymerase II transcription subunit like
SequenceMDGNLKISLDKLPIKRLETIEEVGVERFPSDLGYDEKRVNLIRRIDFAWAVEREDPSKKQKKSSSSSAEAPTAPFPWQSMRENLHLAHQELSVIIDLINTVEANDAVTVAGMTRPKQLPNELLSDLAVSTATKLQCFWSLGKYFKQSAKALERQVAREARFYGALIRLQQNWKVKRQRMVASAPGNEGFYIDLFDNTLHDSAAISRPSAISTVRIEHDPAGMLAVNLPPNSCRSLQFAFLGAYLGDNPRQTSKMQTLYASEDPSKETKKEPKNDDECVKETHSVLREVHRAIFDEQVFDLVNCEAFNPSLGVNVTGIRENYLQLSIGQGASVSIVLVPSRRDNRTVDGAGTQNLEAAIVPLETLDGSTPIKNPGFPNRTSCEIYLEQIFHEQVLGKTKDGSTSARRTHLSNQPAKDGLSFLGHFCMSLAHRIFSTKVLNELENLVAGVPYVHLISQPTWHSRTSSWTLSVNIPQSILHSGRQTQYSGIRCIKDVKSQFRTKVVVNDDCINVVGEGAPNVVGLFKRSESICSMNRYDCDLADLPVILLQQIASQVIRWLHEEALMAGIKAKRDYLSLSFELDQGETLGLVAHVDPEDSEGCISWWLVMDDGFTDEHNIQVEISNGGSDTRKFLGYLSLDVLHSTLMDLVSFCNGGGSL
Length657
PositionHead
OrganismActinidia chinensis var. chinensis
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> Ericales> Actinidiaceae> Actinidia.
Aromaticity0.07
Grand average of hydropathy-0.296
Instability index43.24
Isoelectric point5.84
Molecular weight73118.03
Publications
PubMed=29661190

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP19793
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.18|      17|      31|     362|     378|       1
---------------------------------------------------------------------------
  362-  378 (31.93/19.99)	ETLDGSTPIKNPGFPNR
  396-  412 (29.25/17.74)	KTKDGSTSARRTHLSNQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     186.07|      60|     202|      54|     118|       2
---------------------------------------------------------------------------
   54-  118 (84.52/88.70)	EDPSKKQKKSSSSSAEAPTAPFPwqSMREnLHLAHQELSViIDLINTVEANDA..VTVAGMtRPKQL
  261-  322 (101.55/78.60)	EDPSKETKKEPKNDDECVKETHS..VLRE.VHRAIFDEQV.FDLVNCEAFNPSlgVNVTGI.RENYL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP19793 with Med17 domain of Kingdom Viridiplantae
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