<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP19786

Description Mediator of RNA polymerase II transcription subunit 33A like
SequenceMAVVSVQSSRLWDCVLELTKVAQEKGSDPLLWALQVSSNLNRAGVVLPCPELANLLVSHICWANNVPIAWKFLDKALAFKIAPPLLVLALLSNRVIPNRSSRPAAYRLYMELLKRHALALKSHTEGPNFHKIMNSVDNVLHLSQIFGLEASEPGVIVVEFIFSIVCQLVDASLDDEGLLKLTPEKKSKWVTKSQDMEVASDDNYDEKRIEHQEILQNLNTAMAVELIGQFLQNKVTSRILYLARQNMPLHWGSFVQQIQLLVANSSAVRNSKVTTAEVLQQLATGTCKILSRECKMISPHKFHEVMASASLASSAGLWHGASRSALWLPLDLVLEDLMDGSQVNATSAVEIITGLLKALQAFNGTTWHETFLGLWMAALRLIQRERDPIEGPVPRLDTRLCLLLTISTLVVADLIEEEESAPTDEMECTDSIHGKEKEVPGTRRGDLVSSLQSLGDYKGLLAPPHSVISAANQAAAKAMMFISGINVGTAYFECVSMKDMPLNCSGNMHHLIVEACISRNLLDTSAYFWPGYVNGRINQIPHTLPVQVPSWSSFMKGAPLTSILKNALVSAPASSLAELEKVFEIAVKGLDDEKIAAASILCGASLIRGWNIQEHTAYFISRLLCPPVPADYSGSDSHLISYGPMLNVLLVGIAPVDCVQIFSLHGLVPQLACSLMPICEVFGSCVPNVSWTLPTGDEVSAHAVFSNAFALLLKLWRFNHPPLEHGVGDVPPVGSQLTPEYLLAVRNSHLVSSGNIHSDRCRRRLSSVASSSSPKPIFLDSFPKLKVWYRQHLACIASTLTGLVHGTPVHQIVDGLLNMMFRKINRASQSVTTITSGSSSSSGTGNEDTTLRPKLPAWDVLEAVPFVVDAALTACAHGRLSPRELCTGLKDLADFLPASLATIVSYFSAEVTRGIWKPAFMNGTDWPSPAANLSYVEGQIKKILAATGVDVPSLVSGGRSPATLPLPLAAFVSLTITYKLDKASQRFLNLAGPALETLAAGCPWPCMPIVASLWTQKVKRWSDFLVFSASRTVFLHNNDAVVQLLKSCFTATLGLNVTPISSNGGVGALLGHGFGSHFCGGISPVAPGILYLRVYRSIRDMMFIREEIISLLMQFVREIACSAVSKERMGKLKKAKNGIRYEQVSLATAMTQVKLAASLGASLVWLSGGSALVQSLIKETLPSWFISVHRSEQEESSGGVVAMLAGYALAYFAMLCGAFSWGADSSSSASKRRPKILGTHMEFLASALDGKISLGCNWATWRAYMSGFLSLMVACTPTWVLEVEVEVLKRLSKGLRQWNEEELAFALLGVGGVGTMGVAAELIIESET
Length1328
PositionTail
OrganismActinidia chinensis var. chinensis
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> Ericales> Actinidiaceae> Actinidia.
Aromaticity0.07
Grand average of hydropathy0.211
Instability index43.80
Isoelectric point7.03
Molecular weight144106.49
Publications
PubMed=29661190

Function

Annotated function 
GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of phenylpropanoid metabolic process	GO:2000762	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP19786
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     299.02|      88|      94|    1091|    1184|       1
---------------------------------------------------------------------------
 1053- 1117 (83.92/49.90)	............................LGLNVTPISSN....GGVGA..LLGHGFGSHFCGGISPVAPGILYLRVYRSIRDMMfiREEIISLLMQFVR
 1118- 1209 (130.19/84.84)	EIACSAVSkerMGKLKKAKNGIRYEQVsLATAMTQVKLA....ASLGAS.LVWLSGGSALVQSLIKETLPSWFISVHRSEQEES..SGGVVAMLAGYAL
 1213- 1279 (84.91/45.49)	AMLCGAFS...WGADSSSSASKRRPKI.LGTHMEFLASAldgkISLGCNwATWRAYMSGFL.SLMVACTPTW...........................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      71.34|      20|      75|     700|     720|       2
---------------------------------------------------------------------------
  700-  720 (32.05/25.23)	SAHAVFSNAFAlLLKLWRFNH
  773-  792 (39.29/26.39)	SPKPIFLDSFP.KLKVWYRQH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     213.72|      58|     104|     856|     916|       5
---------------------------------------------------------------------------
  796-  845 (53.10/24.42)	............IASTLTGLVHG..TPvHQIVDGLLNMmfrkINRASQSVTTITSGSSSSSGTG
  856-  914 (95.62/63.97)	PAWDvLEAVPFVVDAALTACAHGRLSP.RELCTGLKDL....ADFLPASLATIVSYFSAEVTRG
  929-  973 (65.00/35.34)	PAAN.LSYVEGQIKKILAAT..GVDVP..SLVSGGRSP....AT.LPLPLAAFVS.........
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.00|      13|      74|     644|     656|       7
---------------------------------------------------------------------------
  644-  656 (22.54/13.54)	PMLNVLLVGIAPV
  669-  681 (25.46/16.34)	PQLACSLMPICEV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.08|      21|      27|      78|      98|      10
---------------------------------------------------------------------------
   78-   98 (35.98/25.27)	AFKIAPPLL...VLALLSNRVIPN
  105-  128 (32.10/21.62)	AYRLYMELLkrhALALKSHTEGPN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     105.85|      33|      61|     188|     220|      13
---------------------------------------------------------------------------
  188-  220 (56.55/41.83)	KWVTKSQDME..VASDDNYDEKRIEHQEILQNLNT
  250-  284 (49.30/35.49)	HWGSFVQQIQllVANSSAVRNSKVTTAEVLQQLAT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     132.07|      39|     125|     474|     512|      14
---------------------------------------------------------------------------
  474-  512 (74.77/56.34)	AAAKAM...MFISGINV..GTAYFECVSM.KDMPLNCSGNMHHLI
  596-  640 (57.30/41.14)	AAASILcgaSLIRGWNIqeHTAYFISRLLcPPVPADYSGSDSHLI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      80.29|      22|     956|      43|      64|      15
---------------------------------------------------------------------------
   43-   64 (42.16/22.46)	AGVVLPC.PELANLLVSHIC.WAN
 1000- 1023 (38.13/19.64)	AGCPWPCmPIVASLWTQKVKrWSD
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP19786 with Med33 domain of Kingdom Viridiplantae
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