<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP19784

Description Mediator of RNA polymerase II transcription subunit 26b
SequenceMAKKSGSLDNWRNYFRASNSDIFDIIEHAILVAASDCPQEFRLRRDKIAETLFSCKLAKCLRCDSVVLSVPGDGGGDEDDDDDGCKIDGYGFEAGGSKESKVNSSRDDQAEMNVNQMSNYSYGEAEALTDEIEEESQIVGEVLRIKEILDNCQDESDSGLFDSLRRLQLMDLSVDKLRATEIGKSVNALRKHASKEIRHLARTLIEVWKDMVDEWVNATAAIGGAEGTPESVNPSVVDEEEEEGLPSPPLDEVFLATQTTMELSQFFDGMDDDGNPRNSSGEFNKNRQTGRKPSRENQNVPKRNPQVPHEPYVPAKDKKSEEMKKQGPILKKQAALVRPHRPSNTESGLVRPTKANVEHKVGIETKFQQRSEKPTLQKKPVADQQDKSKCLDDAARLEAAKRKLHERYQQAENAKRQRTIQVMELHDLPKQGLGGHRNANMRPGNHNRHWANGRR
Length455
PositionUnknown
OrganismActinidia chinensis var. chinensis
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> Ericales> Actinidiaceae> Actinidia.
Aromaticity0.05
Grand average of hydropathy-0.945
Instability index53.87
Isoelectric point5.72
Molecular weight51085.33
Publications
PubMed=29661190

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP19784
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     240.92|      76|     187|      81|     160|       1
---------------------------------------------------------------------------
   81-  160 (118.41/81.60)	DDDGCKIDGYGfEAGGSKESKVNSSRDDQAEMNVN.QMSNYSYGEAEaltDEIEEESQIVGEVLRIKEIL..DNCQDESDSGL
  271-  349 (122.51/73.34)	DDDGNPRNSSG.EFNKNRQTGRKPSRENQNVPKRNpQVPHEPYVPAK...DKKSEEMKKQGPILKKQAALvrPHRPSNTESGL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.83|      14|      19|     404|     417|       3
---------------------------------------------------------------------------
  404-  417 (24.11/17.59)	LHERYQQAENAKRQ
  425-  438 (25.72/19.29)	LHDLPKQGLGGHRN
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP19784 with Med26 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ATAAIGGAEGTPESVNPSVVDEEEEEGLPSPPLDEVFLATQ
2) MELSQFFDGMDDDGNPRNSSGEFNKNRQTGRKPSRENQNVPKRNPQVPHEPYVPAKDKKSEEMKKQGPILKKQAALVRPHRPSNTESGLVRPTKANVEHKVGIETKFQQRSEKPTLQKKPVADQQDKSKCLDDAARLEAAKRKLHERYQQAENAKRQRTIQVMELHDLPKQGLGGHRNANMRPGNHNRHWANGRR
218
261
258
455










Molecular Recognition Features






MoRF SequenceStartStop




1) CLDDAA
2) ILKKQAALVRPHR
3) RHWANG
4) WRNYFR
390
329
448
11
395
341
453
16