<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP19781

Description Mediator of RNA polymerase II transcription subunit 36a like
SequenceMRPPRGRDGGRGRGDRGGGFGGGRGRGGFGGGRGDRGGAMRGRGGFGGGRGGGGGRGRGRGGGGGRGGMKGGSRVVVEPHRHEGVFIVKGKEDALSTKNMVPGEAVYNEKRISVQNEDGTKVEYRVWNPFRSKLAAAILGGVDDVWIVPGARVLYLGAASGTTVSHVSDIVGPNGVVYAVEFSHRSGRDLVNMAKKRTNVIPIIEDARHPAKYRMLVGMVDVIFSDVAQPDQARILALNASYFLKAGGHFVISIKANCIDSTVPAEAVFAQEVKKLQAEQFKPIEQVTLEPFERDHACVVGAYRVPKKQKAAAAAAAS
Length318
PositionUnknown
OrganismActinidia chinensis var. chinensis
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> Ericales> Actinidiaceae> Actinidia.
Aromaticity0.07
Grand average of hydropathy-0.341
Instability index29.15
Isoelectric point10.22
Molecular weight33429.64
Publications
PubMed=29661190

Function

Annotated function
GO - Cellular Component
GO - Biological Function
methyltransferase activity	GO:0008168	IEA:UniProtKB-KW
RNA binding	GO:0003723	IEA:UniProtKB-KW
GO - Biological Process
methylation	GO:0032259	IEA:UniProtKB-KW
rRNA processing	GO:0006364	IEA:UniProtKB-KW

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP19781
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     139.99|      15|      15|      24|      38|       1
---------------------------------------------------------------------------
    5-   18 (32.94/ 9.90)	RGRDG.GRGRGD.RGG
   24-   38 (38.40/12.70)	RGRGGFGGGRGD.RGG
   41-   55 (38.09/12.54)	RGRGGFGGGRGG.GGG
   58-   72 (30.56/ 8.68)	RGRGG.GGGRGGmKGG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.27|      14|      17|     203|     216|       2
---------------------------------------------------------------------------
  203-  216 (25.29/16.10)	IIEDARHPAKYRML
  223-  236 (23.99/14.96)	IFSDVAQPDQARIL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     151.20|      50|     176|      83|     137|       3
---------------------------------------------------------------------------
   84-  137 (75.59/75.57)	GVFIVKGKEDALSTKnmVPGEAVYNEKRISVQNEDGTKVE.................YRVwnPFRSKLAAA
  248-  314 (75.61/53.68)	GHFVISIKANCIDST..VPAEAVFAQEVKKLQAEQFKPIEqvtlepferdhacvvgaYRV..PKKQKAAAA
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP19781 with Med36 domain of Kingdom Viridiplantae

Intrinsically Disordered Regions

IDR SequenceStartStop
1) MRPPRGRDGGRGRGDRGGGFGGGRGRGGFGGGRGDRGGAMRGRGGFGGGRGGGGGRGRGRGGGGGRGGMKGGSRVV
1
76

Molecular Recognition Features

MoRF SequenceStartStop
1) MRPPRGRDGGRGRGDRGGGFGGGRGRGGFGGGRGDRGGAMRGRGGFGGGRGGGGGRGRGRG
1
61