Description | Mediator of RNA polymerase II transcription subunit like |
Sequence | MDIISQLQEQANTIAALAFNTFGTLQRDAPPVRLSPNYPEPPANPTEDAANVAEQPKLMSAALVKAAKQFDALVAALPLSEGGEDAQLKRIAELQAENDAVGQELQRQLEAAEKELKQVQELFSQAADNCLNLKKPD |
Length | 137 |
Position | Middle |
Organism | Actinidia chinensis var. chinensis |
Kingdom | Viridiplantae |
Lineage | Eukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> Ericales> Actinidiaceae> Actinidia. |
Aromaticity | 0.04 |
Grand average of hydropathy | -0.415 |
Instability index | 57.12 |
Isoelectric point | 4.48 |
Molecular weight | 14807.48 |
Publications | PubMed=29661190 |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU366036 |
GO - Cellular Component | mediator complex GO:0016592 IEA:UniProtKB-UniRule |
GO - Biological Function | |
GO - Biological Process |
Binary Interactions |
Repeats | >MDP19773 --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 74.56| 26| 27| 71| 96| 1 --------------------------------------------------------------------------- 71- 96 (40.19/27.65) DALVAALPLSEGGEDAQLKRIAEL..QA 99- 126 (34.37/22.56) DAVGQELQRQLEAAEKELKQVQELfsQA --------------------------------------------------------------------------- |
MoRF Sequence | Start | Stop |
1) EDAANVAEQPKLMSAALVKAAKQFDALVAALPL 2) EDAQLKRIAELQAENDAVG 3) VRLSPNYPEP | 47 84 32 | 79 102 41 |
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