<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP19771

Description Mediator of RNA polymerase II transcription subunit like
SequenceMNPNKDSEEESPTVATSSSSALEAAKGSEKADGDEEEAAENGEDPMEEDHPVNPAAVFCIRLKQPRSNLMHKMSVPELCRNFSAVAWCGKLNAIACASETCARIPSSNANPPFWIPIHIVIPERPTECAVFNVIADSPRDSVQFMEWSPTSCPRALLIANFHGRITIWTQPSQGLPNLVRDASCWHREHEWRQDIAVVTKWLSGVSPYRWLSSRSSNPASSKSTFEEKFLSQQPQAPAGWPNFLCVCSVFSSGSVQLHWAQWPPNQSGAASKWFCTSKGLLGAGPSGIMAADAIITDNGAMHVAGVPIVNPSTVVVWEVTPGPGNGFQATPKASTATGVPPSLNPPSWDGFASLAAYLFNWQEYFLLEAKQGKKHTDQDYSDMVSLHCSPVSNFSAYVSPEAAAQSAATTTWGSGVTAVAFDPTRGGSVIAVVIVEGQYMSPYDPDEGPSITGWRVQRWESSLKPVVLHQIFGNPTSTFGGQVPMQTVWVTTVNKCITPTKDFKIHQAAVAGPCSDVRNTSDSGLEKTKRVCFDPFDLPSDVRTLARIVYSAHGGEIAVAFLRGGVHIFSGASFAPVDNYQIDVGSAIAAPAFSSTSCCSASVWHDTSKDRTILKMIRVLPPAVQSSQAKANSSTWERAIAERFWWSLLVGVDWWDAVGCTQSAAEDGIVSLNSVIAVLDADFHSLPSTQHRQLYGPSLDRIKCRLLEGTNAQEVRAMVLDMQARLLLDMLGKGIESALINPAALVSEPWQETGEKLSLIDPETMAVEPALVLSIQAYVDSVLDLASHFITRLRRYASFCRTLASHAVTAGTGGNRNMVASPTQNSATPATSQGGQGGTASSTGSTQMQAWVQGAIAKISSTADGVPNSTPNPISGPSSFMPISINTGTFPGTPAVRLIGDCRFLHRLCQLLLFCFFFRRTQLRFIGGAPRNADTNMQKPQPGAPGKVEEISSVPTKPTSGMARSDEMQAARGGQAISGTKGPEEGPASRSRLGSGNAGQGYTFEEVKVLFLILLDLCRRTAGLAHPLPVSQVGSNNIQVRLHYIDGNYTVLPEVVEASLGPHMQNMPRPRGADAAGLLLRELELHPPAEEWHRRNMFGGPWSDPEDMGPSDDPPKLSNSSDLLELNSLENCDIYDGANGLWPRKRRMSERDAAFGLNTSVGLGAYLGIMGSRRDVVTAVWKTGLEGMWFKCIRCLRQTSAFAAPGPSTPPNQNEREMWWISRWAYGCPMCGGTWVRVV
Length1239
PositionTail
OrganismActinidia chinensis var. chinensis
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> Ericales> Actinidiaceae> Actinidia.
Aromaticity0.08
Grand average of hydropathy-0.204
Instability index44.66
Isoelectric point6.02
Molecular weight133848.82
Publications
PubMed=29661190

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP19771
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     694.77|     193|     525|     155|     354|       1
---------------------------------------------------------------------------
   70-  300 (314.04/138.42)	MHKMSVPeLCRNFSAV........AWC...GKLNAIACA...SETCARIPSSnA.NPPFW................................................................................................................................................................................................................................................................................................ipihiviperptecavfnviadsprdsvqfmewsptscprALLIANFHGRITIWTQPSQGLPNLVRDASCWHREHEWR..QD...I.AVV....TKWLSGVSPYRWLSSR..SSNPAS..SKSTFE..EKFLSQQPQAPAGWPNFLCVCSVFSSG...SVQLHWAQWPPNQSGA.ASKWFCT..SKGLLGAGPSGIMAADAIITDNGA
  301-  350 (13.09/11.51)	MHVAGVP.IVNPSTVV........VWEvTPGPGNGFQATpK.ASTATGVPPS.L.NPPSWdG..............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................
  677-  827 (169.63/70.38)	..............................................................faslaaylfnwqeyflleakqgkkhtdqdysdmvslhcspvsnfsayvspeaaaqsaatttwgsgvtavafdptrggsviavvivegqymspydpdegpsitgwrvqrwesslkpvvlhqifgnptstfggqvpmqtvwvttvnkcitptkdfkihqaavagpcsdvrntsdsglektkrvcfdpfdlpsdvrtlarivysahggeiavaflrggvhifsgasfapvdnyqidvgsaiaapafsstsccsasvwhdtskdrtilkmirvlppavqssqakansstweraiaerfwwsllvgvdwwdavgctqsaaedgivslnsviAVLDADFHSLPSTQHRQLYG.PSLDR.IKCRLLEGTNA..QE...VrAMVldmqARLLLDMLG.KGIESA..LINPAAlvSEPWQEtgEKLSLIDPETMAVEPALVLSIQAYVDS...VLDLA.SHFITRLRRY.AS..FCRtlASHAVTAGTGGNRNMVASPTQNSA
  828-  999 (198.02/84.80)	TPATS.Q.GGQGGTASstgstqmqAW..VQG...AIA...KiSSTADGVPNS.TpNPIS..G......................................................................................................................................................................................................................................................................................................................................................PSSFMPISI.NTGTFPGTPAVRliGDcrfL.HRL....CQLLLFCFFFRRTQLRfiGGAPRN..ADTNMQ..K....PQPGAPGKVEEISSVPTKPTSGmarSDEMQAARGGQAISGTkGPEEGPA..SRSRLGSGNAG.............
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     116.23|      34|      74|     390|     425|       3
---------------------------------------------------------------------------
  390-  425 (54.36/37.29)	PVSNFSAYVSPEAAAQSAATTTWGSgvTAVAFDPTR
  576-  609 (61.87/36.56)	PVDNYQIDVGSAIAAPAFSSTSCCS..ASVWHDTSK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     126.27|      36|     573|     614|     660|       4
---------------------------------------------------------------------------
  617-  660 (54.94/51.04)	IRVLPPAvqSSQAKANSSTWERAIAERFWWsllvgVDWWdAVGC
 1193- 1228 (71.33/36.26)	IRCLRQT..SAFAAPGPSTPPNQNEREMWW.....ISRW.AYGC
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP19771 with Med16 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GAPRNADTNMQKPQPGAPGKVEEISSVPTKPTSGMARSDEMQAARGGQAISGTKGPEEGPASRSRLGSGN
2) GTGGNRNMVASPTQNSATPATSQGGQGGTASSTGS
3) MNPNKDSEEESPTVATSSSSALEAAKGSEKADGDEEEAAENGEDPMEEDH
928
811
1
997
845
50










Molecular Recognition Features






MoRF SequenceStartStop




1) SSALEAAKGSE
19
29